MYOB1_ARATH
ID MYOB1_ARATH Reviewed; 1113 AA.
AC F4HXQ7; Q8GXM3; Q9FRQ9;
DT 04-FEB-2015, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 25-MAY-2022, entry version 64.
DE RecName: Full=Myosin-binding protein 1 {ECO:0000303|PubMed:23995081};
GN Name=MYOB1 {ECO:0000303|PubMed:23995081};
GN OrderedLocusNames=At1g08800 {ECO:0000312|Araport:AT1G08800};
GN ORFNames=F22O13.29 {ECO:0000312|EMBL:AAF99773.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|Proteomes:UP000006548};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP FUNCTION, INTERACTION WITH XI-K; XI-I AND XI-1, DOMAIN, TISSUE SPECIFICITY,
RP SUBCELLULAR LOCATION, AND DISRUPTION PHENOTYPE.
RX PubMed=23995081; DOI=10.1105/tpc.113.113704;
RA Peremyslov V.V., Morgun E.A., Kurth E.G., Makarova K.S., Koonin E.V.,
RA Dolja V.V.;
RT "Identification of myosin XI receptors in Arabidopsis defines a distinct
RT class of transport vesicles.";
RL Plant Cell 25:3022-3038(2013).
CC -!- FUNCTION: Membrane-anchored myosin receptors that define a distinct,
CC plant-specific transport vesicle compartment.
CC {ECO:0000269|PubMed:23995081}.
CC -!- SUBUNIT: Interacts with myosin XI-K, XI-I and XI-1.
CC {ECO:0000269|PubMed:23995081}.
CC -!- SUBCELLULAR LOCATION: Endomembrane system
CC {ECO:0000269|PubMed:23995081}; Single-pass membrane protein
CC {ECO:0000255}.
CC -!- TISSUE SPECIFICITY: Expressed in leaf epidermal cells, roots and root
CC hairs. {ECO:0000269|PubMed:23995081}.
CC -!- DOMAIN: The GTD-binding domain is sufficient for myosin binding. The
CC transmembrane region (1-61) is sufficient for the membrane targeting.
CC {ECO:0000269|PubMed:23995081}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype. Myob1 and myob2 double
CC mutant has no visible phenotype, but a delayed flowering. Myob1, myob2
CC and myob3 triple mutant has a significant height reduction and a
CC delayed flowering. Myob1, myob2, myob3 and myob4 quadruple mutant has a
CC significant height reduction, a reduced rosette diameter and a delayed
CC flowering. {ECO:0000269|PubMed:23995081}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF99773.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC003981; AAF99773.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE28348.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE28349.1; -; Genomic_DNA.
DR EMBL; CP002684; ANM59414.1; -; Genomic_DNA.
DR EMBL; CP002684; ANM59415.1; -; Genomic_DNA.
DR EMBL; AK118159; BAC42783.1; -; mRNA.
DR PIR; A86220; A86220.
DR PIR; T00736; T00736.
DR RefSeq; NP_001117250.1; NM_001123778.2.
DR RefSeq; NP_001318957.1; NM_001331788.1.
DR RefSeq; NP_001321772.1; NM_001331789.1.
DR RefSeq; NP_172357.2; NM_100754.3.
DR AlphaFoldDB; F4HXQ7; -.
DR SMR; F4HXQ7; -.
DR STRING; 3702.AT1G08800.2; -.
DR iPTMnet; F4HXQ7; -.
DR PaxDb; F4HXQ7; -.
DR PRIDE; F4HXQ7; -.
DR ProteomicsDB; 251356; -.
DR EnsemblPlants; AT1G08800.1; AT1G08800.1; AT1G08800.
DR EnsemblPlants; AT1G08800.2; AT1G08800.2; AT1G08800.
DR EnsemblPlants; AT1G08800.3; AT1G08800.3; AT1G08800.
DR EnsemblPlants; AT1G08800.4; AT1G08800.4; AT1G08800.
DR GeneID; 837402; -.
DR Gramene; AT1G08800.1; AT1G08800.1; AT1G08800.
DR Gramene; AT1G08800.2; AT1G08800.2; AT1G08800.
DR Gramene; AT1G08800.3; AT1G08800.3; AT1G08800.
DR Gramene; AT1G08800.4; AT1G08800.4; AT1G08800.
DR KEGG; ath:AT1G08800; -.
DR Araport; AT1G08800; -.
DR TAIR; locus:2825149; AT1G08800.
DR eggNOG; ENOG502QPSJ; Eukaryota.
DR HOGENOM; CLU_009392_2_0_1; -.
DR InParanoid; F4HXQ7; -.
DR OMA; EDSTEDC; -.
DR OrthoDB; 372111at2759; -.
DR PRO; PR:F4HXQ7; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; F4HXQ7; baseline and differential.
DR Genevisible; F4HXQ7; AT.
DR GO; GO:0016021; C:integral component of membrane; IDA:UniProtKB.
DR GO; GO:0030133; C:transport vesicle; IDA:UniProtKB.
DR GO; GO:0017022; F:myosin binding; IPI:UniProtKB.
DR GO; GO:0080115; F:myosin XI tail binding; IDA:TAIR.
DR InterPro; IPR007656; GTD-bd.
DR InterPro; IPR039306; MYOB.
DR PANTHER; PTHR31448; PTHR31448; 3.
DR Pfam; PF04576; Zein-binding; 1.
DR PROSITE; PS51775; GTD_BINDING; 1.
PE 1: Evidence at protein level;
KW Coiled coil; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..1113
FT /note="Myosin-binding protein 1"
FT /id="PRO_0000431707"
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 888..986
FT /note="GTD-binding"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01111"
FT REGION 209..229
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 721
FT /note="C -> R (in Ref. 3; BAC42783)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 1113 AA; 125428 MW; 67B7E624AFB16781 CRC64;
MGSRSFTRAL ALAFNEWLLM FMLFVNSIFS YVIARFADYS ELQSPCLMCS NLDHILRRTK
DLKKTHWDII CSKHKSEISS LVYCHAHGKL VDVRGMCETC LFSFATTNKS NAETYRLLVG
KLGEDSHFGS KSDRSKYPNC SKLTDCTCCN QLWTPQTAAT QVAEREILPK IGLLGKIRTG
KQSAPKKSVS FNHLPDVGYT ELKIHSDTES EAVFSDTEPK QESSLNHLPP VGYNEPKIGL
VGDVRTGKPS TPKKSVSFNH LPDVGYTELK IHSDTESEAV FSEDECVVLK DEDHKYQIVD
LQTHPIITLP YDLATDKLLN FDFPLEPFVT RNDREEVQLQ ETNWRTYSSF PVLIPVNDVP
ETSEKVFKEE EINSLDNLFL TSRAMKHFAA AKVKEEPIRL QDISSTPDVK ENPANASLME
ETELICLSDV TATSGAMEHS EVILKEREEL IHLQDISVTP DFKENPANAS LLEETELICL
NDVTSPLRAV EHSAVLLKDK VEPIRLQDGG SLTPDFMENS ANASILEETE LICVNDVTST
SRTMGHSSVV LKENEEPIRF QDSSLTPDFK ENPASTFLVE ETELICLNDV TSPSRAMEHS
TVFIEEKEEL VRHQNITLTQ DFMENPANSS LREETELICL NDVTSTSEVA ETPEDVLEGI
ELMSIHDISL DEVSESVTTN QTSVEISKER DTDQADITSL ESEYIVVPSP NSMPENSTDN
CVSDKKEMKE TSLRISSLSE MAPRDVTSHT EAALESESSS FNSMSVAAET NQYSGELLDL
ADAYNIVVGN EGHYDSNGRQ QIENWMKKDT SRVSEDLKAL LTQISASRGI EFLSPRDVSP
KISVNSSDQE TKNLDHDMQL LLQKRMLERN ESNLSLEGVS VTEIEGESEG DRLKRQVDYD
RKLLTGLYKE LEEERSASAV ATNQAMAMIT RLQEEKASFQ MEALQNLRMM EEQAEYDMEA
IQRLNDLLVE REKLIQDLEA EIEYFRDQTP QKKNKLDVAE KVTEMDSPSE GMSNKIQSCL
VGFDEERLYI TSCLEKIENR VNGKAHDDNL PAQESVSELH ERVERLKGDL YFLEQVMNSL
GHGNEGVQFV KEIASHLQTL RSLSMKRQDQ TEC
