MYOB3_ARATH
ID MYOB3_ARATH Reviewed; 675 AA.
AC Q0WNW4; Q9LFE5;
DT 04-FEB-2015, integrated into UniProtKB/Swiss-Prot.
DT 05-SEP-2006, sequence version 1.
DT 03-AUG-2022, entry version 90.
DE RecName: Full=Myosin-binding protein 3 {ECO:0000303|PubMed:23995081};
GN Name=MYOB3 {ECO:0000303|PubMed:23995081};
GN OrderedLocusNames=At5g16720 {ECO:0000312|Araport:AT5G16720};
GN ORFNames=F5E19.60 {ECO:0000312|EMBL:CAC01836.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|EMBL:BAF01185.1};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP FUNCTION, INTERACTION WITH XI-K, DOMAIN, AND DISRUPTION PHENOTYPE.
RX PubMed=23995081; DOI=10.1105/tpc.113.113704;
RA Peremyslov V.V., Morgun E.A., Kurth E.G., Makarova K.S., Koonin E.V.,
RA Dolja V.V.;
RT "Identification of myosin XI receptors in Arabidopsis defines a distinct
RT class of transport vesicles.";
RL Plant Cell 25:3022-3038(2013).
CC -!- FUNCTION: Membrane-anchored myosin receptors that define a distinct,
CC plant-specific transport vesicle compartment.
CC {ECO:0000269|PubMed:23995081}.
CC -!- SUBUNIT: Interacts with myosin XI-K. {ECO:0000269|PubMed:23995081}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Single-pass membrane
CC protein {ECO:0000255}.
CC -!- DOMAIN: The GTD-binding domain is sufficient for myosin binding.
CC {ECO:0000269|PubMed:23995081}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype. Myob1, myob2 and myob3
CC triple mutant has a significant height reduction and a delayed
CC flowering. Myob1, myob2, myob3 and myob4 quadruple mutant has a
CC significant height reduction, a reduced rosette diameter and a delayed
CC flowering. {ECO:0000269|PubMed:23995081}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAC01836.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AL391147; CAC01836.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED92330.1; -; Genomic_DNA.
DR EMBL; AK229322; BAF01185.1; -; mRNA.
DR PIR; T51504; T51504.
DR RefSeq; NP_197174.2; NM_121678.3.
DR AlphaFoldDB; Q0WNW4; -.
DR SMR; Q0WNW4; -.
DR STRING; 3702.AT5G16720.1; -.
DR iPTMnet; Q0WNW4; -.
DR PaxDb; Q0WNW4; -.
DR PRIDE; Q0WNW4; -.
DR ProteomicsDB; 251221; -.
DR EnsemblPlants; AT5G16720.1; AT5G16720.1; AT5G16720.
DR GeneID; 831534; -.
DR Gramene; AT5G16720.1; AT5G16720.1; AT5G16720.
DR KEGG; ath:AT5G16720; -.
DR Araport; AT5G16720; -.
DR TAIR; locus:2149025; AT5G16720.
DR eggNOG; ENOG502QPIG; Eukaryota.
DR HOGENOM; CLU_009392_0_0_1; -.
DR InParanoid; Q0WNW4; -.
DR OMA; CMSSAKK; -.
DR OrthoDB; 289983at2759; -.
DR PhylomeDB; Q0WNW4; -.
DR PRO; PR:Q0WNW4; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q0WNW4; baseline and differential.
DR Genevisible; Q0WNW4; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0017022; F:myosin binding; IPI:UniProtKB.
DR GO; GO:0080115; F:myosin XI tail binding; IDA:TAIR.
DR InterPro; IPR007656; GTD-bd.
DR InterPro; IPR039306; MYOB.
DR PANTHER; PTHR31448; PTHR31448; 2.
DR Pfam; PF04576; Zein-binding; 1.
DR PROSITE; PS51775; GTD_BINDING; 1.
PE 1: Evidence at protein level;
KW Coiled coil; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..675
FT /note="Myosin-binding protein 3"
FT /id="PRO_0000431709"
FT TRANSMEM 17..37
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 355..453
FT /note="GTD-binding"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01111"
FT REGION 225..274
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 286..315
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 474..497
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 542..565
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 582..605
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 605..633
FT /evidence="ECO:0000255"
FT COMPBIAS 474..492
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 675 AA; 77021 MW; D3D56150A83A467C CRC64;
MAANNFATKL SRNTNRITVI LVYAFLEWLL MFFIFLNSFF TYFIVKFASF FGLKQVCLLC
PKLDRIFERK PENRFTYKEL LCQNHIAELA SLSFCRTHGK LSESANLCSD CSNREEEQSN
IGLGFCTCCQ KSLADKPYPN YLLLKSSIWG KTLGDREDGG LILEMIDDDK FGDGFEIDRE
SYPLGFFRDK AEEGKKQDQQ QNGEVISDVE SYGLSLREVS EEDGLRSIIS NNSPGNEAKS
RVSEDEQRND DTSNVATYGE DQISGRVEEK EEETGVADLL YDQFESKNFT GSQIEEEEED
REETTKELDP ETPTSVSTLF NKKLHFLARN EYAAAEDAGD GNVLVSEMDG GDPLRTIERL
RETVRAEQEA LRDLYAELEE ERSASAISAN QTMAMITRLQ EEKAKVQMEA LQYQRMMEEQ
AEYDQEALQL LNHLMVKREK EKEQLQRELE VYRAKVLEYE SKAKNKIIVV ENDCEADDDD
KEEENREEDN SSEMDVDLEK ITLDCVQHMS MLGESLSEFE EERLVILDQL KVLEDRLVTM
QDKESAEDPG EFSNSYEEAS NGHGGLTMAS MAKSLLPLLD AAENESEDGS QGLPESDEKN
FGSDSEKLEI IKQVDSVYER LQELETDGEF LKNCMSSAKK GDKGTDILKD ILQHLRDLRT
IELTNTIENQ TTQEE
