ID   MYOD1_CAEBR             Reviewed;         329 AA.
AC   Q17295; A8XHP0;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   03-AUG-2022, entry version 118.
DE   RecName: Full=Myoblast determination protein 1 homolog;
DE            Short=MyoD protein 1;
GN   Name=hlh-1; ORFNames=CBG13470;
OS   Caenorhabditis briggsae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6238;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7958441; DOI=10.1006/dbio.1994.1302;
RA   Krause M., Harrison S.W., Xu S.Q., Chen L., Fire A.;
RT   "Elements regulating cell- and stage-specific expression of the C. elegans
RT   MyoD family homolog hlh-1.";
RL   Dev. Biol. 166:133-148(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16;
RX   PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA   Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA   Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA   Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA   Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA   Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA   Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA   Durbin R.M., Waterston R.H.;
RT   "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT   genomics.";
RL   PLoS Biol. 1:166-192(2003).
CC   -!- FUNCTION: Accumulation defines the body wall muscle cell fate during
CC       embryogenesis.
CC   -!- SUBUNIT: Efficient DNA binding requires dimerization with another bHLH
CC       protein.
CC   -!- SUBCELLULAR LOCATION: Nucleus.
CC   -!- TISSUE SPECIFICITY: Body wall muscle cells; in clonal muscle
CC       precursors, in a set of early embryonic blastomeres (the ms-
CC       granddaughters), and in six glial-like cells called GLRS.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; U05000; AAA74943.1; -; Genomic_DNA.
DR   EMBL; HE600919; CAP32157.3; -; Genomic_DNA.
DR   RefSeq; XP_002630090.1; XM_002630044.1.
DR   AlphaFoldDB; Q17295; -.
DR   SMR; Q17295; -.
DR   STRING; 6238.CBG13470; -.
DR   PRIDE; Q17295; -.
DR   GeneID; 8572906; -.
DR   KEGG; cbr:CBG_13470; -.
DR   CTD; 8572906; -.
DR   WormBase; CBG13470a; CBP40297; WBGene00034231; Cbr-hlh-1.
DR   eggNOG; KOG3960; Eukaryota.
DR   HOGENOM; CLU_872198_0_0_1; -.
DR   InParanoid; Q17295; -.
DR   OMA; IMEQNQH; -.
DR   OrthoDB; 1433570at2759; -.
DR   Proteomes; UP000008549; Chromosome II.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.
DR   GO; GO:0045663; P:positive regulation of myoblast differentiation; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   Gene3D; 4.10.280.10; -; 1.
DR   InterPro; IPR011598; bHLH_dom.
DR   InterPro; IPR036638; HLH_DNA-bd_sf.
DR   InterPro; IPR039704; Myogenic_factor.
DR   PANTHER; PTHR11534; PTHR11534; 1.
DR   Pfam; PF00010; HLH; 1.
DR   SMART; SM00353; HLH; 1.
DR   SUPFAM; SSF47459; SSF47459; 1.
DR   PROSITE; PS50888; BHLH; 1.
PE   2: Evidence at transcript level;
KW   Developmental protein; Differentiation; DNA-binding; Myogenesis; Nucleus;
KW   Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..329
FT                   /note="Myoblast determination protein 1 homolog"
FT                   /id="PRO_0000127372"
FT   DOMAIN          160..211
FT                   /note="bHLH"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
FT   REGION          256..279
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   329 AA;  36595 MW;  4774896E33266B1C CRC64;
     MNQTETSTAP ANAETYDTNI YYTPSPRVTA NDITTLTTFA TPVPQALDYV NTQYNDIYRN
     QPATYYLPTY GQPGSSSFYP DFSNFNVART QDFAALPTVA ADIKPIIIKQ EKEVSSGGSN
     NNDPTSTDLL GDGVAHSGDE TAPIATLVAG ANAPRRTKLD RRKAATMRER RRLRKVNEAF
     EVVKQRTCPN PNQRLPKVEI LRSAIDYINT LERMLTSVGK TTKIMDQNHH LQMTQPISAA
     PHDYITSSHF ANAGYNPDGP NVYDDEDLSD TDEDRDHHHH KLGNAIDLRR RNSLDGLARI
     VDNIPLLQSQ PEVPNEIPAG SEDKKLEIL