ID   MYOD1_ONCMY             Reviewed;         276 AA.
AC   Q91205;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Myoblast determination protein 1 homolog 1;
DE   AltName: Full=Myogenic factor 1-1;
GN   Name=myod1; Synonyms=myod;
OS   Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Oncorhynchus.
OX   NCBI_TaxID=8022;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Muscle;
RX   PubMed=8018722; DOI=10.1016/0167-4781(94)90012-4;
RA   Rescan P.Y., Gauvry L., Paboeuf G., Fauconneau B.;
RT   "Identification of a muscle factor related to MyoD in a fish species.";
RL   Biochim. Biophys. Acta 1218:202-204(1994).
CC   -!- FUNCTION: May act as a transcriptional activator that promotes
CC       transcription of muscle-specific target genes and plays a role in
CC       muscle differentiation. {ECO:0000250}.
CC   -!- SUBUNIT: Efficient DNA binding requires dimerization with another bHLH
CC       protein.
CC   -!- SUBCELLULAR LOCATION: Nucleus.
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DR   EMBL; X75798; CAA53436.1; -; mRNA.
DR   PIR; S45362; S38629.
DR   RefSeq; NP_001118192.1; NM_001124720.1.
DR   AlphaFoldDB; Q91205; -.
DR   SMR; Q91205; -.
DR   Ensembl; ENSOMYT00000068817; ENSOMYP00000063209; ENSOMYG00000029242.
DR   Ensembl; ENSOMYT00000068826; ENSOMYP00000063218; ENSOMYG00000061213.
DR   GeneID; 100136773; -.
DR   KEGG; omy:100136773; -.
DR   CTD; 778924; -.
DR   GeneTree; ENSGT00950000182959; -.
DR   OrthoDB; 1471470at2759; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0031490; F:chromatin DNA binding; ISS:UniProtKB.
DR   GO; GO:0070888; F:E-box binding; ISS:UniProtKB.
DR   GO; GO:1990841; F:promoter-specific chromatin binding; ISS:UniProtKB.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0071392; P:cellular response to estradiol stimulus; ISS:UniProtKB.
DR   GO; GO:0043966; P:histone H3 acetylation; ISS:UniProtKB.
DR   GO; GO:0043967; P:histone H4 acetylation; ISS:UniProtKB.
DR   GO; GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.
DR   GO; GO:1905382; P:positive regulation of snRNA transcription by RNA polymerase II; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; ISS:UniProtKB.
DR   Gene3D; 4.10.280.10; -; 1.
DR   InterPro; IPR011598; bHLH_dom.
DR   InterPro; IPR036638; HLH_DNA-bd_sf.
DR   InterPro; IPR022032; Myf5.
DR   InterPro; IPR002546; MyoD_N.
DR   InterPro; IPR039704; Myogenic_factor.
DR   PANTHER; PTHR11534; PTHR11534; 1.
DR   Pfam; PF01586; Basic; 1.
DR   Pfam; PF00010; HLH; 1.
DR   Pfam; PF12232; Myf5; 1.
DR   SMART; SM00520; BASIC; 1.
DR   SMART; SM00353; HLH; 1.
DR   SUPFAM; SSF47459; SSF47459; 1.
DR   PROSITE; PS50888; BHLH; 1.
PE   2: Evidence at transcript level;
KW   Activator; Developmental protein; Differentiation; DNA-binding; Myogenesis;
KW   Nucleus; Transcription; Transcription regulation.
FT   CHAIN           1..276
FT                   /note="Myoblast determination protein 1 homolog 1"
FT                   /id="PRO_0000127368"
FT   DOMAIN          84..135
FT                   /note="bHLH"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
FT   REGION          228..253
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        228..246
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   276 AA;  30707 MW;  7614CF33A341FD86 CRC64;
     MELPDIPFPI TSPDDFYDDP CFNTSDMHFF EDLDPRLVHV GLLKPDDHHH KEDEHIRAPS
     GHHQAGRCLL WACKACKRKT TNADRRKAAT MRERRRLSKV NDAFETLKRC TSTNPNQRLP
     KVDILRNAIS YIESLQGLLR GAGQEGNYYP VMDHYSGDSD ASSPRSNCSD GMMDFNGQSC
     PPRRRNKYDS TYFNEAPNDS RHKKNSVISS LDCLSNIVER ITTDTSACPA VQDGSEGSSP
     CSPGDGSIAS ENGAPIPSPI NCVPALHDPN TIYQVL