MYPOP_XENLA
ID MYPOP_XENLA Reviewed; 341 AA.
AC Q08B72; Q7T0Q7;
DT 22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 31-OCT-2006, sequence version 1.
DT 03-AUG-2022, entry version 56.
DE RecName: Full=Myb-related transcription factor, partner of profilin;
DE AltName: Full=Myb-related protein p42POP;
GN Name=mypop; Synonyms=p42pop;
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo, and Spleen;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Transcriptional repressor; DNA-binding protein that
CC specifically recognizes the core sequence 5'-YAAC[GT]G-3'.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAH56084.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305};
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DR EMBL; BC056084; AAH56084.1; ALT_SEQ; mRNA.
DR EMBL; BC124852; AAI24853.1; -; mRNA.
DR RefSeq; NP_001116348.1; NM_001122876.1.
DR AlphaFoldDB; Q08B72; -.
DR PRIDE; Q08B72; -.
DR DNASU; 398691; -.
DR GeneID; 398691; -.
DR KEGG; xla:398691; -.
DR CTD; 398691; -.
DR Xenbase; XB-GENE-999501; mypop.L.
DR Proteomes; UP000186698; Chromosome 8L.
DR Bgee; 398691; Expressed in testis and 19 other tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR InterPro; IPR028002; Myb_DNA-bind_5.
DR InterPro; IPR001005; SANT/Myb.
DR Pfam; PF13873; Myb_DNA-bind_5; 1.
DR PROSITE; PS50090; MYB_LIKE; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Nucleus; Reference proteome; Repressor; Transcription;
KW Transcription regulation.
FT CHAIN 1..341
FT /note="Myb-related transcription factor, partner of
FT profilin"
FT /id="PRO_0000344801"
FT DOMAIN 8..80
FT /note="Myb-like"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00133"
FT REGION 84..103
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 180..210
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 309..341
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 186..203
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 326..341
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 341 AA; 37786 MW; E4454EB5EEAB2EC8 CRC64;
MSGDTEEVTR LRKPRFSYEE NQILIREVRA HYPMLYGAQS RRLSVAERRR VWEGIAAKIN
AITNWKRTAQ EVQKRWNDFK RRTKEKLARV PHSTQSGTAE EAMTAEEETI FAILGPGVMP
GSSHYGPVTH LGAMDFNPSG PGSSSPETSL SAPCAPIEAP LLLHPKESPS PTSQLHIVQL
PHLTPSPDPS ECPSPPPPGS GTPLLTPSGV AQHYDPTVAM LRAQQETAEA IRHLTYTLRQ
SMDRLTNVLA AILPLVPHQP PESPTPSGIL GPVYYPTKTE PESEPCCPVT YEEENGEDGG
EEEIQEVIAE PPRSPSPPPP NKRKRFGYLS QRKRRGRWKN L