MYSP_ECHGR
ID MYSP_ECHGR Reviewed; 863 AA.
AC P35417;
DT 01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1994, sequence version 1.
DT 25-MAY-2022, entry version 68.
DE RecName: Full=Paramyosin;
OS Echinococcus granulosus (Hydatid tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Taeniidae; Echinococcus;
OC Echinococcus granulosus group.
OX NCBI_TaxID=6210;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=8295903; DOI=10.1007/bf00932508;
RA Muehlschlegel F., Sygulla L., Frosch P., Massetti P., Frosch M.;
RT "Paramyosin of Echinococcus granulosus: cDNA sequence and characterization
RT of a tegumental antigen.";
RL Parasitol. Res. 79:660-666(1993).
CC -!- FUNCTION: Paramyosin is a major structural component of many thick
CC filaments isolated from invertebrate muscles.
CC -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, myofibril. Note=Thick filaments of the
CC myofibrils.
CC -!- SIMILARITY: Belongs to the paramyosin family. {ECO:0000305}.
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DR EMBL; Z21787; CAA79849.1; -; mRNA.
DR PIR; S37040; S37040.
DR AlphaFoldDB; P35417; -.
DR SMR; P35417; -.
DR GO; GO:0030016; C:myofibril; IEA:UniProtKB-SubCell.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0032982; C:myosin filament; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.370; -; 1.
DR InterPro; IPR002928; Myosin_tail.
DR InterPro; IPR014751; XRCC4-like_C.
DR Pfam; PF01576; Myosin_tail_1; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Cytoplasm; Motor protein; Muscle protein; Myosin;
KW Thick filament.
FT CHAIN 1..863
FT /note="Paramyosin"
FT /id="PRO_0000211251"
FT REGION 1..26
FT /note="Nonhelical region"
FT /evidence="ECO:0000255"
FT REGION 837..863
FT /note="Nonhelical region"
FT /evidence="ECO:0000255"
FT COILED 27..836
FT /evidence="ECO:0000255"
SQ SEQUENCE 863 AA; 98741 MW; 6DEC07F4DF26B6A3 CRC64;
MSESHVKISR TIIRGTSPST VRLESPVREL EDLLDLERDA RVRSERNANE LSIQLDTMTE
RLDELSGTSS QTQDAIRRKD MEIANVRKDL ENANAAFETA EATLRRKHNT MISEISSEVE
NLQKQKGRAE KDKSQLMLEI DNVLGQLDGA LKAKASAESK LEGLDSQLTR LKALTDDLQR
QMADVNSAKS RLAAENFELV RVNQEYEAQV VNFSKTKSVL EGQLDDLKRA MDEDARNRLN
LQTQLSSLQM DYDNLQARYE EEAEAAGNLR NQVAKFNADM AALKTRLERE LMAKTEEFEE
LKRKLTVRIT ELEDIAEHER TRANNLEKTK VKLTIEIKDL QAENEALAAE NGELTHRAKQ
AENLANELQR RVDEMTVEIN TLNSANNALE GDNMRLKGQV GDLTDRIANL DRENRQLGDQ
LKETKSALRD ANRRLTDLEA LRSQLEADGD NLASALHDAE EALKELEVKY VASQNALNHL
KSEMEQRLRE KDEELENLRK STTRTIEELT TTISEMEVRF KSDMSRLKKK YEATISELEV
QLDVANKANA SLNRENKALA QRVQELQTAL EDERRAREAA ESNLQVSERK RIALTSEVEE
IRSQLELSDR ARKNAESELN DANGRISELT MSVNTLTNDK RRLEGDIGVM QGDLDEAVNA
RKAAEDRADR LNAEVLRLAD ELRQEQENYK RAETLRKQLE IEIREITVKL EEAEAFATRE
GRRMVQKLQN RVRELEAELD GEIRRAKEAF ASARKYERQF KELQTQSEDD KRMILELQDL
LDKTQIKMKA YKRQLEEQEE VSQLTMSKYR KAQQQIEEAE HRADMAERTI TIKRTIGGPG
SRAVSVVREI NSVSRGNRAT SIM