ID   MYSP_RHIMP              Reviewed;         873 AA.
AC   Q86RN8;
DT   16-FEB-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 50.
DE   RecName: Full=Paramyosin;
GN   Name=PRM;
OS   Rhipicephalus microplus (Cattle tick) (Boophilus microplus).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC   Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Rhipicephalinae;
OC   Rhipicephalus; Boophilus.
OX   NCBI_TaxID=6941;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, AND INTERACTION WITH IGG
RP   AND COLLAGEN.
RX   PubMed=12358423; DOI=10.1017/s0031182002002019;
RA   Ferreira C.A., Barbosa M.C., Silveira T.C., Valenzuela J.G.,
RA   Da Silva Vaz I. Jr., Masuda A.;
RT   "cDNA cloning, expression and characterization of a Boophilus microplus
RT   paramyosin.";
RL   Parasitology 125:265-274(2002).
CC   -!- FUNCTION: Paramyosin is a major structural component of many thick
CC       filaments isolated from invertebrate muscles.
CC   -!- SUBUNIT: Homodimer (By similarity). Binds IgG and collagen.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, myofibril. Note=Thick filaments of the
CC       myofibrils.
CC   -!- TISSUE SPECIFICITY: Expressed in all tissues except in saliva.
CC       {ECO:0000269|PubMed:12358423}.
CC   -!- SIMILARITY: Belongs to the paramyosin family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AF479582; AAO20875.1; -; mRNA.
DR   AlphaFoldDB; Q86RN8; -.
DR   SMR; Q86RN8; -.
DR   VEuPathDB; VectorBase:LOC119177055; -.
DR   GO; GO:0030016; C:myofibril; IEA:UniProtKB-SubCell.
DR   GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR   GO; GO:0032982; C:myosin filament; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.5.370; -; 1.
DR   InterPro; IPR002928; Myosin_tail.
DR   InterPro; IPR014751; XRCC4-like_C.
DR   Pfam; PF01576; Myosin_tail_1; 1.
PE   1: Evidence at protein level;
KW   Coiled coil; Cytoplasm; Motor protein; Muscle protein; Myosin;
KW   Thick filament.
FT   CHAIN           1..873
FT                   /note="Paramyosin"
FT                   /id="PRO_0000211244"
FT   REGION          1..25
FT                   /note="Nonhelical region"
FT                   /evidence="ECO:0000255"
FT   REGION          853..873
FT                   /note="Nonhelical region"
FT                   /evidence="ECO:0000255"
FT   COILED          26..852
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   873 AA;  101992 MW;  D9E42B5BD248BA84 CRC64;
     MSSRSSKYMY KSSGGAGDIS IEYGTDLGAL TRLEDKLRLL QEDLESEREL RQRIEREKSD
     LTVQLMQLSD RLEEAEGSSE TVVEMNKKRD TELSKLRKLL EDVHLESEET AHHLRKKHQE
     AVAEMQEQMD LMTKAKSKAE KERQKFQAEV YELLAQVENT NKEKITIQKT VEKLEHTVYE
     LNIRIEELNR TVTEVTAQRT RLSAENAEYL KEVHELKVSL DNVNHLKSQL ATQLEDTRRR
     LEDEERKRAS LESSMHTLEV EIESLKVQLE EESEARLEVE RQLVKANADA AAYKTKYETE
     VQAHADEVEE LRRKMAQKIS EYEEQLEALL TRCSNLEKQK SRLQSEVEVL IMDLEKATAH
     AQNLEKRVAQ LEKLNIDLKS KVEELTILLE QSQRELRQKV AEIQKLQHEY EKMREQRDAL
     QRENKKLVDD LSEAKSQLAD AIRRLHEYEL EIKRLENERD ELAAAYKEAE TLRKQEEAKC
     QRLTAELAQV RHEYERRLQI KEEEIEALRK QYQLEVEQLN MRLAEAEAKL KTEIARIKKK
     YQAQITELEM SLDAANKQNM DLQKIIKKQA IQITELQAHY DEVHRQLQQC ADQLAISQRR
     CQGLQAELDE QRVALESALR SKRAAEQSLE ESQARVNELT TINVNIAAAK NKLESELSAL
     QADYDELHKE LRVVDERCQR TIVELKSTKD ILVEEQERYI KVESIKKSLE VEVRNLQVRL
     EEVEANALAG GKRVIAKLEA RIRDVEIELE EEKKRHAETQ KILRKKDHRA KELLLQTEED
     HKTITMLNDA VEKLNEKVKV YKRQLNEQEG LSQQNLTRVR RFQRELEAAE DRADSAESNL
     SLIRAKHRSW VTTSQVPGGT RQVFVTEESS QNF