ID   MYSP_SARSC              Reviewed;         876 AA.
AC   Q9BMM8; Q8I9R6;
DT   16-FEB-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   25-MAY-2022, entry version 49.
DE   RecName: Full=Paramyosin;
OS   Sarcoptes scabiei (Itch mite) (Acarus scabiei).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC   Acariformes; Sarcoptiformes; Astigmata; Psoroptidia; Sarcoptoidea;
OC   Sarcoptidae; Sarcoptinae; Sarcoptes.
OX   NCBI_TaxID=52283;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=11393829; DOI=10.1017/s0031182001007648;
RA   Mattsson J.G., Ljunggren E.L., Bergstrom K.;
RT   "Paramyosin from the parasitic mite Sarcoptes scabiei: cDNA cloning and
RT   heterologous expression.";
RL   Parasitology 122:555-562(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 238-876.
RA   Fischer K., Holt D.C., Harumal P., Currie B.J., Walton S.F., Kemp D.J.;
RT   "Generation and characterization of cDNA clones from Sarcoptes scabiei type
RT   hominis for an expressed sequence tag library; identification of homologs
RT   of house dust mite allergens.";
RL   Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Paramyosin is a major structural component of many thick
CC       filaments isolated from invertebrate muscles.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, myofibril. Note=Thick filaments of the
CC       myofibrils.
CC   -!- SIMILARITY: Belongs to the paramyosin family. {ECO:0000305}.
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DR   EMBL; AF317670; AAK01181.1; -; mRNA.
DR   EMBL; AF462195; AAO15612.1; -; mRNA.
DR   AlphaFoldDB; Q9BMM8; -.
DR   SMR; Q9BMM8; -.
DR   VEuPathDB; VectorBase:SSCA005798; -.
DR   Proteomes; UP000070412; Unplaced.
DR   GO; GO:0030016; C:myofibril; IEA:UniProtKB-SubCell.
DR   GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR   GO; GO:0032982; C:myosin filament; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.5.370; -; 2.
DR   InterPro; IPR002928; Myosin_tail.
DR   InterPro; IPR014751; XRCC4-like_C.
DR   Pfam; PF01576; Myosin_tail_1; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Cytoplasm; Motor protein; Muscle protein; Myosin;
KW   Reference proteome; Thick filament.
FT   CHAIN           1..876
FT                   /note="Paramyosin"
FT                   /id="PRO_0000211255"
FT   REGION          1..28
FT                   /note="Nonhelical region"
FT                   /evidence="ECO:0000255"
FT   REGION          856..876
FT                   /note="Nonhelical region"
FT                   /evidence="ECO:0000255"
FT   COILED          29..855
FT                   /evidence="ECO:0000255"
FT   CONFLICT        339
FT                   /note="A -> E (in Ref. 2; AAO15612)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        810..811
FT                   /note="TR -> Q (in Ref. 2; AAO15612)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   876 AA;  102455 MW;  C99475EE7A0DAE52 CRC64;
     MSARSAKFMY RSGNAGASGD LSVEYGTDLG ALTRLEDKIR LLSDDLESER EMRQRIEREK
     AELQIQVMSL SERLEEAEGS SESVVEMNKK RDSELAKLRK LLEDVHLESE ETAHHLRQKH
     QAAIQEMQDQ LDQVQKAKNK SDKEKQKFQA EVFELLAQLE TANKEKLTAM KTVEKLEYTV
     HELNIKIEEI NRTVIELTSQ KTRLSQENTE LIKEVHEHKM QLDNANHLKQ QLAQQLEDTK
     HRLEEEERKR ASLENHAHTL EVELESLKVQ LDEESEARLE LERQLTKANG DAASWKSKYE
     AELQAHADEV EELRRKMAQK ISEYEEQLEA LLNKCSSLAK QKSRLQSEVE VLIMDLEKAT
     THAQQLEKRV AQLEKLNLDL KNKLEEVTML MEQAQKEARA KAAELQKLQH EYEKLRDQRD
     ALARENKKLT DDLAECKSQL NDAHRRIHEQ EIEIKRLENE REELSAAYKE AETLRKQEEA
     KNQRLTAELA QVRHDYEKRL AQKEEEIEAL RKQYQIEIEQ LNMRLAEAEA KLKTEIARLK
     KKYQAQITEL ELSLDAANKA NIDLQKTIKK QALQITELQA HYDEVHRQLQ QAVDQLGVTQ
     RRCQALQAEL EEQRIALEQA NRAKRQAEQL HEEAVARVNE LTTINVNLAS AKSKLESEFA
     ALQNDYDEVH KELRISDERV QKLTIELKST KDLLVEEQER LVKMETVKKS LEQEVRTLHV
     RIEEVEANAL AGGKRVIAKL ESRIRDVEIE VEEERRRHAE TEKMLRKKDH RLKELLVQNE
     EDHKQIQLLQ EMVDKMNEKV KVYKRQMQET REGMSQQNLT RVRRFQRELE AAEDRADQAE
     SNLSFIRAKH RSWVTTSQVP GGTRQVFVTQ EEQSNY