ID   MYS_PODCA               Reviewed;         692 AA.
AC   Q05000;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Myosin heavy chain;
DE   Flags: Fragment;
OS   Podocoryna carnea (Hydrozoan).
OC   Eukaryota; Metazoa; Cnidaria; Hydrozoa; Hydroidolina; Anthoathecata;
OC   Filifera; Hydractiniidae; Podocoryna.
OX   NCBI_TaxID=6096;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=8104835; DOI=10.1111/j.1432-0436.1993.tb00654.x;
RA   Schuchert P., Reber-Mueller S., Schmid V.;
RT   "Life stage specific expression of a myosin heavy chain in the hydrozoan
RT   Podocoryne carnea.";
RL   Differentiation 54:11-18(1993).
CC   -!- FUNCTION: Myosin is a protein that binds to F-actin and has ATPase
CC       activity that is activated by F-actin.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, myofibril. Note=Thick filaments of the
CC       myofibrils.
CC   -!- DEVELOPMENTAL STAGE: Only present in the striated muscle cells of the
CC       medusa stage.
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DR   EMBL; X69057; CAA48795.1; -; mRNA.
DR   AlphaFoldDB; Q05000; -.
DR   SMR; Q05000; -.
DR   PRIDE; Q05000; -.
DR   GO; GO:0030016; C:myofibril; IEA:UniProtKB-SubCell.
DR   GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR   GO; GO:0032982; C:myosin filament; IEA:UniProtKB-KW.
DR   GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.5.370; -; 5.
DR   InterPro; IPR002928; Myosin_tail.
DR   InterPro; IPR014751; XRCC4-like_C.
DR   Pfam; PF01576; Myosin_tail_1; 1.
PE   2: Evidence at transcript level;
KW   Actin-binding; ATP-binding; Coiled coil; Cytoplasm; Motor protein;
KW   Muscle protein; Myosin; Nucleotide-binding; Thick filament.
FT   CHAIN           <1..692
FT                   /note="Myosin heavy chain"
FT                   /id="PRO_0000123386"
FT   REGION          <1..692
FT                   /note="Rodlike tail"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          48..71
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          307..422
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          506..529
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          644..692
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          25..670
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        1..23
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        54..71
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        310..330
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        345..363
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        365..388
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        394..422
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        506..528
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        670..684
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
SQ   SEQUENCE   692 AA;  77884 MW;  A1BD21EC921F33C3 CRC64;
     KVSQLEDDLT TSEAKNTKAA SRSGGLAKQL ADAEHKLGLA TKNIKSLEGA LSDAKSAAED
     ESKGKHDNHQ KLQNALSEIE ALTEQLDEEQ ASRQDLQNKF SRANADAQQW KNKYDTDGAS
     RVEELEDAKR KLANRVQEME EALAAAESKA ASMEKVKNRM NEEVEDLLLD LEKAQAQASN
     LEKKQKKVDQ QINEWKLKCD EIQADLDKAQ RDARGYSTEL LKVRTASEDT IEKYDALKKE
     NRALSAELQS VTEQLSDGGK NSAEVEKLRR KLGMENEELQ IALEEAEAAL EQEEGKLLKV
     QLEYTQLRQS SDRKLSEKDE ELEGLRKNHQ RQMESLQNTI DSESRSKAEQ QKLRKKYDAD
     MMELESQLES SNRVAAESQK QMKKLQAQIK ELQSMIDDES RGRDDMRDSA SRSERRANDL
     AVQLDEARVA LEQAERARKL AENEKSENSD RVAELQALYN NVANAKAEGD YHSLQEEIED
     LENEAKASED KAQRAMAEVA RLMSELNSAQ EATSTAEKSR QLVSKQVADL QSRLEDAEAQ
     GGKGLKNQLR KLEQRIMELE SDVDTEARKG ADAIKAARKS EKKVKELAFT IEDEHKRREP
     AQDTADKLNQ KLKKMRMQLE EAEQQKSTWQ SKYKKAAVEL EDAEERCEAA EAALQKARQR
     ARGASGSATR GASRAPSQPR TPRSKTARAG ED