ID   MYTA_MYTED              Reviewed;          34 AA.
AC   P81612;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   30-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 46.
DE   RecName: Full=Mytilin-A;
OS   Mytilus edulis (Blue mussel).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC   Autobranchia; Pteriomorphia; Mytilida; Mytiloidea; Mytilidae; Mytilinae;
OC   Mytilus.
OX   NCBI_TaxID=6550;
RN   [1]
RP   PROTEIN SEQUENCE, CHARACTERIZATION, AND MASS SPECTROMETRY.
RC   TISSUE=Blood;
RX   PubMed=8702979; DOI=10.1074/jbc.271.36.21808;
RA   Charlet M., Chernysh S., Philippe H., Hetru C., Hoffman J.A., Bulet P.;
RT   "Innate immunity. Isolation of several cysteine-rich antimicrobial peptides
RT   from the blood of a mollusc, Mytilus edulis.";
RL   J. Biol. Chem. 271:21808-21813(1996).
CC   -!- FUNCTION: Has antibacterial activity against A.viridans, B.megaterium,
CC       M.luteus, E.faecalis, S.aureus and E.coli. It is active against the
CC       marine species A.carrageenovora, P.alginovora and C.drobachiensis.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- MASS SPECTROMETRY: Mass=3773.7; Method=MALDI;
CC       Evidence={ECO:0000269|PubMed:8702979};
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DR   AlphaFoldDB; P81612; -.
DR   SMR; P81612; -.
DR   PRIDE; P81612; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0050688; P:regulation of defense response to virus; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Antibiotic; Antimicrobial; Antiviral defense; Antiviral protein;
KW   Direct protein sequencing; Disulfide bond; Immunity; Innate immunity;
KW   Secreted.
FT   PEPTIDE         1..34
FT                   /note="Mytilin-A"
FT                   /id="PRO_0000044690"
FT   DISULFID        2..27
FT                   /evidence="ECO:0000250"
FT   DISULFID        6..29
FT                   /evidence="ECO:0000250"
FT   DISULFID        10..31
FT                   /evidence="ECO:0000250"
FT   DISULFID        15..34
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   34 AA;  3782 MW;  F61805D5500CA698 CRC64;
     GCASRCKAKC AGRRCKGWAS ASFRGRCYCK CFRC