ID   MZM1_AJECN              Reviewed;         153 AA.
AC   A6RD58;
DT   08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 1.
DT   25-MAY-2022, entry version 46.
DE   RecName: Full=Mitochondrial zinc maintenance protein 1, mitochondrial;
DE   Flags: Precursor;
GN   Name=MZM1; ORFNames=HCAG_07566;
OS   Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus)
OS   (Histoplasma capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma;
OC   unclassified Histoplasma.
OX   NCBI_TaxID=2059318;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NAm1 / WU24;
RX   PubMed=19717792; DOI=10.1101/gr.087551.108;
RA   Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA   Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA   McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA   Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA   Henn M.R., Birren B.W., Taylor J.W.;
RT   "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT   and their relatives.";
RL   Genome Res. 19:1722-1731(2009).
CC   -!- FUNCTION: Assembly factor required for Rieske Fe-S protein RIP1
CC       incorporation into the cytochrome b-c1 (CIII) complex. Functions as a
CC       chaperone, binding to this subunit within the mitochondrial matrix and
CC       stabilizing it prior to its translocation and insertion into the late
CC       CIII dimeric intermediate within the mitochondrial inner membrane.
CC       Modulates the mitochondrial matrix zinc pool (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with RIP1. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the complex I LYR family. MZM1 subfamily.
CC       {ECO:0000305}.
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DR   EMBL; CH476663; EDN11113.1; -; Genomic_DNA.
DR   RefSeq; XP_001537257.1; XM_001537207.1.
DR   AlphaFoldDB; A6RD58; -.
DR   SMR; A6RD58; -.
DR   STRING; 339724.A6RD58; -.
DR   EnsemblFungi; EDN11113; EDN11113; HCAG_07566.
DR   GeneID; 5443573; -.
DR   KEGG; aje:HCAG_07566; -.
DR   VEuPathDB; FungiDB:HCAG_07566; -.
DR   HOGENOM; CLU_147114_2_2_1; -.
DR   OMA; CELRIHE; -.
DR   OrthoDB; 1585902at2759; -.
DR   Proteomes; UP000009297; Unassembled WGS sequence.
DR   GO; GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
DR   GO; GO:0034551; P:mitochondrial respiratory chain complex III assembly; IEA:InterPro.
DR   CDD; cd20267; Complex1_LYR_LYRM7; 1.
DR   InterPro; IPR045298; Complex1_LYR_LYRM7.
PE   3: Inferred from homology;
KW   Chaperone; Mitochondrion; Reference proteome; Transit peptide.
FT   TRANSIT         1..56
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           57..153
FT                   /note="Mitochondrial zinc maintenance protein 1,
FT                   mitochondrial"
FT                   /id="PRO_0000405476"
SQ   SEQUENCE   153 AA;  17283 MW;  49210AB9B537BEF8 CRC64;
     MAATTAPNPL AAYRFLLRAT RIAFQGDFTT LHAARAEARK QFDQHRQQGV DTPMRIQHAM
     ETAEILRTNV VQGVKISGDG EEADRYASIL VMRRFRGEYE GEDERREKER EARGGCELRI
     HEHIERGDND SIKTAGKNER VKVAVGKACS NTQ