MZT1_CRYNB
ID MZT1_CRYNB Reviewed; 72 AA.
AC P0CP05; Q560S2; Q5KPS1;
DT 28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 25-MAY-2022, entry version 34.
DE RecName: Full=Mitotic-spindle organizing protein 1;
DE AltName: Full=Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 1;
GN OrderedLocusNames=CNBA1680;
OS Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)
OS (Filobasidiella neoformans).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus neoformans species complex.
OX NCBI_TaxID=283643;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B-3501A;
RX PubMed=15653466; DOI=10.1126/science.1103773;
RA Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D.,
RA Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E.,
RA Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A.,
RA Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C.,
RA Janbon G., Jones S.J.M., Koo H.L., Krzywinski M.I., Kwon-Chung K.J.,
RA Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A.,
RA Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E.,
RA Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A.,
RA Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W.,
RA Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.;
RT "The genome of the basidiomycetous yeast and human pathogen Cryptococcus
RT neoformans.";
RL Science 307:1321-1324(2005).
CC -!- FUNCTION: Required for gamma-tubulin complex recruitment to the
CC microtubule organizing center (MTOC). {ECO:0000250}.
CC -!- SUBUNIT: Part of the gamma-tubulin complex. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center, spindle pole body {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the MOZART1 family. {ECO:0000305}.
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DR EMBL; AAEY01000001; EAL23521.1; -; Genomic_DNA.
DR RefSeq; XP_778168.1; XM_773075.1.
DR AlphaFoldDB; P0CP05; -.
DR SMR; P0CP05; -.
DR EnsemblFungi; AAW40722; AAW40722; CNA01750.
DR EnsemblFungi; EAL23521; EAL23521; CNBA1680.
DR GeneID; 4933419; -.
DR KEGG; cnb:CNBA1680; -.
DR VEuPathDB; FungiDB:CNBA1680; -.
DR HOGENOM; CLU_160285_0_1_1; -.
DR Proteomes; UP000001435; Chromosome 1.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0000931; C:gamma-tubulin large complex; IEA:InterPro.
DR GO; GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell.
DR GO; GO:0033566; P:gamma-tubulin complex localization; IEA:InterPro.
DR InterPro; IPR022214; MZT1.
DR PANTHER; PTHR28520; PTHR28520; 1.
DR Pfam; PF12554; MOZART1; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Cytoskeleton.
FT CHAIN 1..72
FT /note="Mitotic-spindle organizing protein 1"
FT /id="PRO_0000410159"
SQ SEQUENCE 72 AA; 7784 MW; 881498A161AC05D3 CRC64;
MSSTQDEAIL RNARETIDSL YDLSQLLQTG LDKSTLSICV GMIEQGANPD TLAAVIKELR
SENEALNSQS NA