ID   MZT1_CRYNJ              Reviewed;          72 AA.
AC   P0CP04; Q560S2; Q5KPS1;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 1.
DT   25-MAY-2022, entry version 42.
DE   RecName: Full=Mitotic-spindle organizing protein 1;
DE   AltName: Full=Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 1;
GN   OrderedLocusNames=CNA01750;
OS   Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC
OS   MYA-565) (Filobasidiella neoformans).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC   Tremellales; Cryptococcaceae; Cryptococcus;
OC   Cryptococcus neoformans species complex.
OX   NCBI_TaxID=214684;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JEC21 / ATCC MYA-565;
RX   PubMed=15653466; DOI=10.1126/science.1103773;
RA   Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D.,
RA   Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E.,
RA   Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A.,
RA   Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C.,
RA   Janbon G., Jones S.J.M., Koo H.L., Krzywinski M.I., Kwon-Chung K.J.,
RA   Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A.,
RA   Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E.,
RA   Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A.,
RA   Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W.,
RA   Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.;
RT   "The genome of the basidiomycetous yeast and human pathogen Cryptococcus
RT   neoformans.";
RL   Science 307:1321-1324(2005).
CC   -!- FUNCTION: Required for gamma-tubulin complex recruitment to the
CC       microtubule organizing center (MTOC). {ECO:0000250}.
CC   -!- SUBUNIT: Part of the gamma-tubulin complex. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC       center, spindle pole body {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MOZART1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE017341; AAW40722.1; -; Genomic_DNA.
DR   RefSeq; XP_566541.1; XM_566541.1.
DR   AlphaFoldDB; P0CP04; -.
DR   SMR; P0CP04; -.
DR   STRING; 5207.AAW40722; -.
DR   PaxDb; P0CP04; -.
DR   EnsemblFungi; AAW40722; AAW40722; CNA01750.
DR   GeneID; 3253988; -.
DR   KEGG; cne:CNA01750; -.
DR   VEuPathDB; FungiDB:CNA01750; -.
DR   eggNOG; ENOG502S6UI; Eukaryota.
DR   HOGENOM; CLU_160285_0_1_1; -.
DR   InParanoid; P0CP04; -.
DR   OMA; LSICVGM; -.
DR   OrthoDB; 1645115at2759; -.
DR   Proteomes; UP000002149; Chromosome 1.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0000931; C:gamma-tubulin large complex; IEA:InterPro.
DR   GO; GO:0031021; C:interphase microtubule organizing center; IBA:GO_Central.
DR   GO; GO:0005819; C:spindle; IBA:GO_Central.
DR   GO; GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell.
DR   GO; GO:0033566; P:gamma-tubulin complex localization; IEA:InterPro.
DR   GO; GO:0051415; P:microtubule nucleation by interphase microtubule organizing center; IBA:GO_Central.
DR   GO; GO:0090307; P:mitotic spindle assembly; IBA:GO_Central.
DR   InterPro; IPR022214; MZT1.
DR   PANTHER; PTHR28520; PTHR28520; 1.
DR   Pfam; PF12554; MOZART1; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Cytoskeleton; Reference proteome.
FT   CHAIN           1..72
FT                   /note="Mitotic-spindle organizing protein 1"
FT                   /id="PRO_0000365083"
SQ   SEQUENCE   72 AA;  7784 MW;  881498A161AC05D3 CRC64;
     MSSTQDEAIL RNARETIDSL YDLSQLLQTG LDKSTLSICV GMIEQGANPD TLAAVIKELR
     SENEALNSQS NA