ID   MZT1_DANRE              Reviewed;          75 AA.
AC   P0C8Y1;
DT   03-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   03-MAR-2009, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Mitotic-spindle organizing protein 1;
DE   AltName: Full=Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 1;
GN   Name=mzt1; Synonyms=mozart1;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Retina;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for gamma-tubulin complex recruitment to the
CC       centrosome. {ECO:0000250}.
CC   -!- SUBUNIT: Part of the gamma-tubulin complex. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC       center, centrosome {ECO:0000250}. Cytoplasm, cytoskeleton, spindle
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MOZART1 family. {ECO:0000305}.
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DR   EMBL; BC059646; -; NOT_ANNOTATED_CDS; mRNA.
DR   RefSeq; NP_001289735.1; NM_001302806.1.
DR   AlphaFoldDB; P0C8Y1; -.
DR   SMR; P0C8Y1; -.
DR   STRING; 7955.ENSDARP00000126983; -.
DR   Ensembl; ENSDART00000152175; ENSDARP00000126713; ENSDARG00000096668.
DR   GeneID; 100333194; -.
DR   KEGG; dre:100333194; -.
DR   CTD; 440145; -.
DR   ZFIN; ZDB-GENE-090313-33; mzt1.
DR   eggNOG; ENOG502S6UI; Eukaryota.
DR   GeneTree; ENSGT00390000005954; -.
DR   HOGENOM; CLU_160285_0_0_1; -.
DR   InParanoid; P0C8Y1; -.
DR   OMA; LSICVGM; -.
DR   OrthoDB; 1645115at2759; -.
DR   Reactome; R-DRE-380270; Recruitment of mitotic centrosome proteins and complexes.
DR   Reactome; R-DRE-380320; Recruitment of NuMA to mitotic centrosomes.
DR   PRO; PR:P0C8Y1; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 1.
DR   Bgee; ENSDARG00000096668; Expressed in somite and 28 other tissues.
DR   ExpressionAtlas; P0C8Y1; baseline and differential.
DR   GO; GO:0005813; C:centrosome; ISS:UniProtKB.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0000931; C:gamma-tubulin large complex; ISS:UniProtKB.
DR   GO; GO:0031021; C:interphase microtubule organizing center; IBA:GO_Central.
DR   GO; GO:0005819; C:spindle; ISS:UniProtKB.
DR   GO; GO:0033566; P:gamma-tubulin complex localization; ISS:UniProtKB.
DR   GO; GO:0051415; P:microtubule nucleation by interphase microtubule organizing center; IBA:GO_Central.
DR   GO; GO:0090307; P:mitotic spindle assembly; IBA:GO_Central.
DR   InterPro; IPR022214; MZT1.
DR   PANTHER; PTHR28520; PTHR28520; 1.
DR   Pfam; PF12554; MOZART1; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Cytoskeleton; Reference proteome.
FT   CHAIN           1..75
FT                   /note="Mitotic-spindle organizing protein 1"
FT                   /id="PRO_0000366192"
SQ   SEQUENCE   75 AA;  8054 MW;  FC471E6EEC6E609B CRC64;
     MASPASANMN AVRETMDVLL EISRLLNTGL DMESLSICVR LCEQGINPEA LSSVIKELRR
     ASDSLKASEN STSQG