MZT1_XENLA
ID MZT1_XENLA Reviewed; 72 AA.
AC Q5U4M5;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 20-MAY-2008, sequence version 2.
DT 03-AUG-2022, entry version 46.
DE RecName: Full=Mitotic-spindle organizing protein 1;
DE AltName: Full=Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 1;
GN Name=mzt1; Synonyms=mozart1;
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Kidney;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for gamma-tubulin complex recruitment to the
CC centrosome. {ECO:0000250}.
CC -!- SUBUNIT: Part of the gamma-tubulin complex. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center, centrosome {ECO:0000250}. Cytoplasm, cytoskeleton, spindle
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the MOZART1 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAH85033.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; BC085033; AAH85033.1; ALT_INIT; mRNA.
DR RefSeq; NP_001165186.1; NM_001171715.1.
DR AlphaFoldDB; Q5U4M5; -.
DR SMR; Q5U4M5; -.
DR PRIDE; Q5U4M5; -.
DR DNASU; 495466; -.
DR GeneID; 495466; -.
DR KEGG; xla:495466; -.
DR CTD; 495466; -.
DR Xenbase; XB-GENE-6253829; mzt1.S.
DR OrthoDB; 1645115at2759; -.
DR Proteomes; UP000186698; Chromosome 2S.
DR Bgee; 495466; Expressed in muscle tissue and 19 other tissues.
DR GO; GO:0005813; C:centrosome; ISS:UniProtKB.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0000931; C:gamma-tubulin large complex; ISS:UniProtKB.
DR GO; GO:0005819; C:spindle; ISS:UniProtKB.
DR GO; GO:0033566; P:gamma-tubulin complex localization; ISS:UniProtKB.
DR InterPro; IPR022214; MZT1.
DR PANTHER; PTHR28520; PTHR28520; 1.
DR Pfam; PF12554; MOZART1; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Cytoskeleton; Reference proteome.
FT CHAIN 1..72
FT /note="Mitotic-spindle organizing protein 1"
FT /id="PRO_0000337017"
SQ SEQUENCE 72 AA; 7743 MW; 56EC209D9AB47630 CRC64;
MANASGNMSA VRETMDVLLE ISRLLNTGLD METLSICVRL CEQGINPEAL SSVIKELRRA
SDTLKASEST AS