MZT1_XENTR
ID MZT1_XENTR Reviewed; 72 AA.
AC Q0VFD6;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-SEP-2006, sequence version 1.
DT 03-AUG-2022, entry version 64.
DE RecName: Full=Mitotic-spindle organizing protein 1;
DE AltName: Full=Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 1;
GN Name=mzt1; Synonyms=mozart1;
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=N6; TISSUE=Ovary;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for gamma-tubulin complex recruitment to the
CC centrosome. {ECO:0000250}.
CC -!- SUBUNIT: Part of the gamma-tubulin complex. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center, centrosome {ECO:0000250}. Cytoplasm, cytoskeleton, spindle
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the MOZART1 family. {ECO:0000305}.
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DR EMBL; BC118868; AAI18869.1; -; mRNA.
DR AlphaFoldDB; Q0VFD6; -.
DR SMR; Q0VFD6; -.
DR STRING; 8364.ENSXETP00000052973; -.
DR PaxDb; Q0VFD6; -.
DR eggNOG; ENOG502S6UI; Eukaryota.
DR HOGENOM; CLU_160285_0_0_1; -.
DR InParanoid; Q0VFD6; -.
DR OMA; LSICVGM; -.
DR TreeFam; TF328444; -.
DR Reactome; R-XTR-380270; Recruitment of mitotic centrosome proteins and complexes.
DR Reactome; R-XTR-380320; Recruitment of NuMA to mitotic centrosomes.
DR Proteomes; UP000008143; Genome assembly.
DR Proteomes; UP000790000; Unplaced.
DR Bgee; ENSXETG00000024541; Expressed in egg cell and 13 other tissues.
DR ExpressionAtlas; Q0VFD6; differential.
DR GO; GO:0005813; C:centrosome; ISS:UniProtKB.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0000931; C:gamma-tubulin large complex; ISS:UniProtKB.
DR GO; GO:0031021; C:interphase microtubule organizing center; IBA:GO_Central.
DR GO; GO:0005819; C:spindle; ISS:UniProtKB.
DR GO; GO:0033566; P:gamma-tubulin complex localization; ISS:UniProtKB.
DR GO; GO:0051415; P:microtubule nucleation by interphase microtubule organizing center; IBA:GO_Central.
DR GO; GO:0090307; P:mitotic spindle assembly; IBA:GO_Central.
DR InterPro; IPR022214; MZT1.
DR PANTHER; PTHR28520; PTHR28520; 1.
DR Pfam; PF12554; MOZART1; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Cytoskeleton; Reference proteome.
FT CHAIN 1..72
FT /note="Mitotic-spindle organizing protein 1"
FT /id="PRO_0000337018"
SQ SEQUENCE 72 AA; 7730 MW; 56FDC0288B558630 CRC64;
MANASGSMSA VRETMDVLLE ISRLLNTGLD METLSICVRL CEQGINPEAL SSVIKELRRA
SETLKASEST AS