MZT2B_XENTR
ID MZT2B_XENTR Reviewed; 170 AA.
AC Q28DB1;
DT 10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT 04-APR-2006, sequence version 1.
DT 03-AUG-2022, entry version 67.
DE RecName: Full=Mitotic-spindle organizing protein 2B;
DE AltName: Full=Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 2B;
GN Name=mzt2b; Synonyms=fam128, mozart2; ORFNames=TEgg010b01.1;
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Egg;
RG Sanger Xenopus tropicalis EST/cDNA project;
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=N6; TISSUE=Ovary;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Part of the gamma-tubulin complex. Interacts with TUBG1 (By
CC similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center, centrosome {ECO:0000250}. Cytoplasm, cytoskeleton, spindle
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the MOZART2 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CR855602; CAJ81722.1; -; mRNA.
DR EMBL; BC155371; AAI55372.1; -; mRNA.
DR RefSeq; NP_001039072.1; NM_001045607.1.
DR AlphaFoldDB; Q28DB1; -.
DR SMR; Q28DB1; -.
DR STRING; 8364.ENSXETP00000018153; -.
DR PaxDb; Q28DB1; -.
DR Ensembl; ENSXETT00000018153; ENSXETP00000018153; ENSXETG00000008275.
DR GeneID; 733867; -.
DR KEGG; xtr:733867; -.
DR CTD; 80097; -.
DR Xenbase; XB-GENE-5737867; mzt2b.
DR eggNOG; ENOG502S50R; Eukaryota.
DR HOGENOM; CLU_105461_0_0_1; -.
DR InParanoid; Q28DB1; -.
DR OMA; MCAGQRA; -.
DR OrthoDB; 1453946at2759; -.
DR PhylomeDB; Q28DB1; -.
DR TreeFam; TF333013; -.
DR Reactome; R-XTR-380270; Recruitment of mitotic centrosome proteins and complexes.
DR Reactome; R-XTR-380320; Recruitment of NuMA to mitotic centrosomes.
DR Proteomes; UP000008143; Chromosome 1.
DR Proteomes; UP000790000; Unplaced.
DR Bgee; ENSXETG00000008275; Expressed in brain and 14 other tissues.
DR GO; GO:0005813; C:centrosome; ISS:UniProtKB.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0000931; C:gamma-tubulin large complex; ISS:UniProtKB.
DR GO; GO:0005819; C:spindle; ISS:UniProtKB.
DR InterPro; IPR024332; MOZART2.
DR PANTHER; PTHR28578; PTHR28578; 1.
DR Pfam; PF12926; MOZART2; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Cytoskeleton; Reference proteome.
FT CHAIN 1..170
FT /note="Mitotic-spindle organizing protein 2B"
FT /id="PRO_0000338990"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 102..170
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 120..170
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 170 AA; 17691 MW; 412361EFF9EDFAD0 CRC64;
MSRGQTEGSQ AMASSQAAGP GPSPDAIVSV SGTVQKYVAK KKKVLNPEEA ELYELTQAAG
IVIDQEVFKI LVDLLKMNVA PLAVFQMLKS MCAGHRIADT VSADSSSISL APGHSDVRGR
NKPNPTTSTT QGPGERSSRE GSSQRIPRQP SGSRMQKSSS SGKSSGGSST