MZT2_DANRE
ID MZT2_DANRE Reviewed; 153 AA.
AC Q6DC17;
DT 10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2004, sequence version 1.
DT 03-AUG-2022, entry version 71.
DE RecName: Full=Mitotic-spindle organizing protein 2;
DE AltName: Full=Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 2;
GN Name=mzt2; Synonyms=fam128, mozart2; ORFNames=zgc:101080;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Part of the gamma-tubulin complex. Interacts with TUBG1 (By
CC similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center, centrosome {ECO:0000250}. Cytoplasm, cytoskeleton, spindle
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the MOZART2 family. {ECO:0000305}.
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DR EMBL; BC078275; AAH78275.1; -; mRNA.
DR RefSeq; NP_001003568.1; NM_001003568.2.
DR AlphaFoldDB; Q6DC17; -.
DR SMR; Q6DC17; -.
DR GeneID; 445174; -.
DR CTD; 80097; -.
DR ZFIN; ZDB-GENE-040801-87; mzt2b.
DR InParanoid; Q6DC17; -.
DR PhylomeDB; Q6DC17; -.
DR Reactome; R-DRE-380270; Recruitment of mitotic centrosome proteins and complexes.
DR Reactome; R-DRE-380320; Recruitment of NuMA to mitotic centrosomes.
DR PRO; PR:Q6DC17; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Unplaced.
DR GO; GO:0005813; C:centrosome; ISS:UniProtKB.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0000931; C:gamma-tubulin large complex; ISS:UniProtKB.
DR GO; GO:0005819; C:spindle; ISS:UniProtKB.
DR InterPro; IPR024332; MOZART2.
DR PANTHER; PTHR28578; PTHR28578; 1.
DR Pfam; PF12926; MOZART2; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Cytoskeleton; Reference proteome.
FT CHAIN 1..153
FT /note="Mitotic-spindle organizing protein 2"
FT /id="PRO_0000338989"
FT REGION 80..153
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 153 AA; 16171 MW; 8D523183B65DF7AD CRC64;
MPSAPDSPSL SVNVSGNVQK YSIKKKKVLN AEETELFELT QAAGVVIDQE VFKIIVDLLK
MNVAPLAVFQ TLKTMCAGQK VSETSTGDAS STSHTTAVPT ESRVRSKMSS GQGEKSARES
SSQRVPRQVS ATRGQKSTKS SGSSSSSSQL TSN