N190_PIG
ID N190_PIG Reviewed; 53 AA.
AC P82126;
DT 13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 23-FEB-2022, entry version 36.
DE RecName: Full=Neuronal protein NP-190;
DE Flags: Fragments;
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823;
RN [1] {ECO:0000305}
RP PROTEIN SEQUENCE, FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, AND
RP DEVELOPMENTAL STAGE.
RC TISSUE=Fetal brain {ECO:0000269|PubMed:9538211};
RX PubMed=9538211; DOI=10.1093/oxfordjournals.jbchem.a021941;
RA Ho S.-C., Wakatsuki S., Arioka M., Yamasaki M., Kitamoto K.;
RT "Identification and characterization of porcine NP-190, a novel protein
RT that is specifically expressed in the axonal membrane during the embryonic
RT period.";
RL J. Biochem. 123:332-338(1998).
CC -!- FUNCTION: Neuronal antigen that may play a role in brain development.
CC May be involved in neurite formation or axonal guidance.
CC {ECO:0000269|PubMed:9538211}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000269|PubMed:9538211}.
CC -!- TISSUE SPECIFICITY: Mainly expressed in the fetal brain where it is
CC specifically localized to the proximal axonal segments, cell bodies and
CC growth cones. Lower level of expression was also detected in the fetal
CC heart and the skeletal muscle. No expression in kidney, liver, lung or
CC spleen. {ECO:0000269|PubMed:9538211}.
CC -!- DEVELOPMENTAL STAGE: Developmentally regulated. Present only during
CC embryonic and neonatal stages. {ECO:0000269|PubMed:9538211}.
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DR eggNOG; KOG1792; Eukaryota.
DR Proteomes; UP000008227; Unplaced.
DR Proteomes; UP000314985; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
PE 1: Evidence at protein level;
KW Developmental protein; Direct protein sequencing; Membrane;
KW Reference proteome.
FT CHAIN <1..>53
FT /note="Neuronal protein NP-190"
FT /id="PRO_0000311682"
FT NON_CONS 19..20
FT /evidence="ECO:0000303|PubMed:9538211"
FT NON_CONS 38..39
FT /evidence="ECO:0000303|PubMed:9538211"
FT NON_TER 1
FT /evidence="ECO:0000303|PubMed:9538211"
FT NON_TER 53
FT /evidence="ECO:0000303|PubMed:9538211"
SQ SEQUENCE 53 AA; 6010 MW; D030BBE451B08D78 CRC64;
VAHDRKFKNV QPKDXXKVPA IAVANPKEEV IVKNKDEKMA DLRNVPKXDV IXK