N2_VARV
ID N2_VARV Reviewed; 177 AA.
AC P0DSQ2; P34019;
DT 16-OCT-2019, integrated into UniProtKB/Swiss-Prot.
DT 16-OCT-2019, sequence version 1.
DT 29-SEP-2021, entry version 10.
DE RecName: Full=Protein N2;
GN ORFNames=N2L, P2L;
OS Variola virus.
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus.
OX NCBI_TaxID=10255;
OH NCBI_TaxID=9606; Homo sapiens (Human).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=Bangladesh-1975;
RX PubMed=8264798; DOI=10.1038/366748a0;
RA Massung R.F., Esposito J.J., Liu L.I., Qi J., Utterback T.R., Knight J.C.,
RA Aubin L., Yuran T.E., Parsons J.M., Loparev V.N., Selivanov N.A.,
RA Cavallaro K.F., Kerlavage A.R., Mahy B.W.J., Venter J.C.;
RT "Potential virulence determinants in terminal regions of variola smallpox
RT virus genome.";
RL Nature 366:748-751(1993).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=Congo-1965, and Somalia-1977;
RA Massung R.F., Loparev V.N., Knight J.C., Chizhikov V.E., Parsons J.M.,
RA Totmenin A.V., Shchelkunov S.N., Esposito J.J.;
RL Submitted (DEC-1994) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Might have a role in the suppression of host immune response.
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the poxviridae N2 protein family. {ECO:0000305}.
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DR EMBL; L22579; AAA60765.1; -; Genomic_DNA.
DR EMBL; U18340; AAA69428.1; -; Genomic_DNA.
DR EMBL; U18337; AAA69322.1; -; Genomic_DNA.
DR PIR; T28455; T28455.
DR RefSeq; NP_042061.1; NC_001611.1.
DR GeneID; 1486482; -.
DR KEGG; vg:1486482; -.
DR Proteomes; UP000119805; Genome.
DR InterPro; IPR022819; Poxvirus_Bcl-2-like.
DR Pfam; PF06227; Poxvirus; 1.
PE 3: Inferred from homology;
FT CHAIN 1..177
FT /note="Protein N2"
FT /id="PRO_0000448209"
SQ SEQUENCE 177 AA; 21023 MW; CC16ACA262932D4C CRC64;
MSSSTMDNNE PKVLEMVYDS PILPEGSSMD PNIINCINRH INMCLQHTYS SSIIAILDRF
LMMNKDELNN TQCHIIKEFM TYEQMAIDHY GGYVNAILYQ IRKRPNQHHT IDLFKKIKRT
RYDTFKVDPV EFVKKVIGFV SILNKYKPVY SYVLYENVLY DELKCFIDYV ETKYFQN