ID   NAA20_DICDI             Reviewed;         173 AA.
AC   Q8SSN5; B0M0P9; Q551T5;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 2.
DT   25-MAY-2022, entry version 99.
DE   RecName: Full=N-alpha-acetyltransferase 20;
DE            EC=2.3.1.-;
DE   AltName: Full=N-acetyltransferase 5 homolog;
DE   AltName: Full=N-terminal acetyltransferase B complex catalytic subunit NAA20 homolog;
DE   AltName: Full=NatB catalytic subunit;
GN   Name=nat5; ORFNames=DDB_G0276345;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=12097910; DOI=10.1038/nature00847;
RA   Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA   Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA   Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA   Noegel A.A.;
RT   "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL   Nature 418:79-85(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Seems to be involved in N-acetylation. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the acetyltransferase family. ARD1 subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AAFI02000014; EAL69253.2; -; Genomic_DNA.
DR   RefSeq; XP_643184.2; XM_638092.2.
DR   AlphaFoldDB; Q8SSN5; -.
DR   SMR; Q8SSN5; -.
DR   STRING; 44689.DDB0238097; -.
DR   PaxDb; Q8SSN5; -.
DR   EnsemblProtists; EAL69253; EAL69253; DDB_G0276345.
DR   GeneID; 8620455; -.
DR   KEGG; ddi:DDB_G0276345; -.
DR   dictyBase; DDB_G0276345; naa20.
DR   eggNOG; KOG3234; Eukaryota.
DR   HOGENOM; CLU_013985_7_1_1; -.
DR   InParanoid; Q8SSN5; -.
DR   OMA; SGEIMGY; -.
DR   PhylomeDB; Q8SSN5; -.
DR   PRO; PR:Q8SSN5; -.
DR   Proteomes; UP000002195; Chromosome 2.
DR   GO; GO:0005737; C:cytoplasm; ISS:dictyBase.
DR   GO; GO:0031416; C:NatB complex; IBA:GO_Central.
DR   GO; GO:0004596; F:peptide alpha-N-acetyltransferase activity; ISS:dictyBase.
DR   GO; GO:0017196; P:N-terminal peptidyl-methionine acetylation; ISS:dictyBase.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR000182; GNAT_dom.
DR   Pfam; PF00583; Acetyltransf_1; 1.
DR   SUPFAM; SSF55729; SSF55729; 1.
DR   PROSITE; PS51186; GNAT; 1.
PE   3: Inferred from homology;
KW   Acyltransferase; Reference proteome; Transferase.
FT   CHAIN           1..173
FT                   /note="N-alpha-acetyltransferase 20"
FT                   /id="PRO_0000327578"
FT   DOMAIN          2..151
FT                   /note="N-acetyltransferase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00532"
SQ   SEQUENCE   173 AA;  20006 MW;  5D2D294B3DB8F237 CRC64;
     MTTIRRFVCD DLFKFNNINL DYLTETYYLP FYLQYLSKWP SLLSMAEDVN GKPMGYMIGK
     AEGEGINWHG HVTAVSVAPE FRRIGLADRL MHILEEGSEK IYDGYFVDLF VRKSNTLAIN
     MYTKFGYSVY RTVIGYYSGD EDALDMRKAL PRDVEKKSII PLKHPVYPTD ADL