ID   NAA35_CHICK             Reviewed;         725 AA.
AC   Q5ZHV2;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=N-alpha-acetyltransferase 35, NatC auxiliary subunit;
DE   AltName: Full=Protein MAK10 homolog;
GN   Name=NAA35; Synonyms=MAK10; ORFNames=RCJMB04_32o21;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: Auxillary component of the N-terminal acetyltransferase C
CC       (NatC) complex which catalyzes acetylation of N-terminal methionine
CC       residues. Involved in regulation of apoptosis and proliferation of
CC       smooth muscle cells.
CC   -!- SUBUNIT: Component of the N-terminal acetyltransferase C (NatC)
CC       complex, which is composed of NAA35, NAA38 and NAA30. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MAK10 family. {ECO:0000305}.
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DR   EMBL; AJ721032; CAG32691.1; -; mRNA.
DR   AlphaFoldDB; Q5ZHV2; -.
DR   SMR; Q5ZHV2; -.
DR   STRING; 9031.ENSGALP00000020543; -.
DR   PaxDb; Q5ZHV2; -.
DR   VEuPathDB; HostDB:geneid_427461; -.
DR   eggNOG; KOG2343; Eukaryota.
DR   InParanoid; Q5ZHV2; -.
DR   PhylomeDB; Q5ZHV2; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0031417; C:NatC complex; ISS:UniProtKB.
DR   GO; GO:0017196; P:N-terminal peptidyl-methionine acetylation; IEA:InterPro.
DR   GO; GO:0006474; P:N-terminal protein amino acid acetylation; IBA:GO_Central.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
DR   GO; GO:0048659; P:smooth muscle cell proliferation; ISS:UniProtKB.
DR   InterPro; IPR007244; Naa35/Mak10.
DR   PANTHER; PTHR21373; PTHR21373; 1.
DR   Pfam; PF04112; Mak10; 2.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..725
FT                   /note="N-alpha-acetyltransferase 35, NatC auxiliary
FT                   subunit"
FT                   /id="PRO_0000308619"
FT   REGION          548..573
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   725 AA;  83539 MW;  2C37B807710A07CD CRC64;
     MVMKASVEDD DSGWELGMPD KMEKSNTDWV DITQDFEEAC RELKLGELLH DKLFGLFEAM
     SAIEMMDPKM DAGMIGNQVN RKVLNFEQAI KDGTIKIKDL TSPELIGIMD TCFCCLITWL
     EGHSLAQTVF TCLYIHNPDF IEDPAMKAFA LGILKICDIA REKVNKAAVF EEEDFQSMTY
     GFKMANSVTD LRVTGMLKDV EDDMQRRVKS TRSRQGEERD PEVELEHQQC LAVFSRVKFT
     RVLLTVLIAF TKKETSAVAE AQELMTQAAD LLSAIHNSCI HGIQAQNDTT KGDHPIMMGF
     EPLVNQRLLP PTFPRYAKII KREEMVNYFS KLIDRIKTVC EVVNLTNLHC ILDFFCEFSE
     QSPCVLSRSL LQTTFLVDNK KVFGTHLMQD MVKDALRSFV SPPVLSPKCC LYNNHQAKDY
     IDSFVTHCVR PFCSLIQIHG HNRARQRDKL GHILEEFATL QDEAEKVDAA LHSMLLKQEP
     QRQHLACLGT WVLYHNLRIM IQYLLSGFEL ELYSMHEYYY IYWYLSEFLY AWLMSTLSRA
     DSSQMAEERI MEEQQKGRSS KKTKKKKKVR PLSREITMSQ AYQNMCAGMY KTMIAFDMDG
     KVRKPKFELD SEQVRYEHRF APFNSVITPP PVHYLQFKEM SDLNKYSPPP QSADLYMAAS
     KHFQQAKMIL ENIPNPDHEV NRILKVAKPN IVVMKLLAGG HKKDSKVPPE FDFSPHKYFP
     VVKLV