NAC25_ARATH
ID NAC25_ARATH Reviewed; 323 AA.
AC Q8GY42; O22734; Q8LAF7;
DT 28-NOV-2012, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 25-MAY-2022, entry version 108.
DE RecName: Full=NAC transcription factor 25;
DE Short=AtNAC025;
GN Name=NAC025; Synonyms=ANAC025, NAC25, TAPNAC; OrderedLocusNames=At1g61110;
GN ORFNames=F11P17.16;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [6]
RP FUNCTION.
RX PubMed=18849494; DOI=10.1105/tpc.108.060160;
RA Kunieda T., Mitsuda N., Ohme-Takagi M., Takeda S., Aida M., Tasaka M.,
RA Kondo M., Nishimura M., Hara-Nishimura I.;
RT "NAC family proteins NARS1/NAC2 and NARS2/NAM in the outer integument
RT regulate embryogenesis in Arabidopsis.";
RL Plant Cell 20:2631-2642(2008).
RN [7]
RP TISSUE SPECIFICITY, AND DEVELOPMENTAL STAGE.
RX PubMed=21107887; DOI=10.1007/s11103-010-9713-5;
RA Alvarado V.Y., Tag A., Thomas T.L.;
RT "A cis regulatory element in the TAPNAC promoter directs tapetal gene
RT expression.";
RL Plant Mol. Biol. 75:129-139(2011).
CC -!- FUNCTION: Transcription factor of the NAC family. May be associated
CC with anther development and pollen production (Probable). Required for
CC normal seed development and morphology (PubMed:18849494).
CC {ECO:0000269|PubMed:18849494, ECO:0000305|PubMed:21107887}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00353}.
CC -!- TISSUE SPECIFICITY: Expressed specifically in the tapetum.
CC {ECO:0000269|PubMed:21107887}.
CC -!- DEVELOPMENTAL STAGE: Expressed during pollen development and
CC maturation. {ECO:0000269|PubMed:21107887}.
CC -!- DOMAIN: The NAC domain includes a DNA-binding domain and a dimerization
CC domain. {ECO:0000255|PROSITE-ProRule:PRU00353}.
CC -!- MISCELLANEOUS: Plants silencing NAC025 produce abnormally shaped seeds.
CC {ECO:0000269|PubMed:18849494}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAB71483.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=AAB71483.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AC002294; AAB71483.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE33783.1; -; Genomic_DNA.
DR EMBL; AK117878; BAC42518.1; -; mRNA.
DR EMBL; AY087839; AAM65392.1; -; mRNA.
DR EMBL; BT008346; AAP37705.1; -; mRNA.
DR PIR; H96636; H96636.
DR RefSeq; NP_564771.1; NM_104792.3.
DR AlphaFoldDB; Q8GY42; -.
DR SMR; Q8GY42; -.
DR STRING; 3702.AT1G61110.1; -.
DR PaxDb; Q8GY42; -.
DR PRIDE; Q8GY42; -.
DR EnsemblPlants; AT1G61110.1; AT1G61110.1; AT1G61110.
DR GeneID; 842404; -.
DR Gramene; AT1G61110.1; AT1G61110.1; AT1G61110.
DR KEGG; ath:AT1G61110; -.
DR Araport; AT1G61110; -.
DR TAIR; locus:2008490; AT1G61110.
DR eggNOG; ENOG502QRBC; Eukaryota.
DR HOGENOM; CLU_035664_8_1_1; -.
DR InParanoid; Q8GY42; -.
DR OMA; YRMGHEA; -.
DR OrthoDB; 1189960at2759; -.
DR PhylomeDB; Q8GY42; -.
DR PRO; PR:Q8GY42; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q8GY42; baseline and differential.
DR Genevisible; Q8GY42; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0043565; F:sequence-specific DNA binding; IDA:TAIR.
DR GO; GO:0009793; P:embryo development ending in seed dormancy; IMP:UniProtKB.
DR GO; GO:0009831; P:plant-type cell wall modification involved in multidimensional cell growth; IMP:TAIR.
DR GO; GO:0010628; P:positive regulation of gene expression; IDA:TAIR.
DR GO; GO:0048731; P:system development; IBA:GO_Central.
DR Gene3D; 2.170.150.80; -; 1.
DR InterPro; IPR003441; NAC-dom.
DR InterPro; IPR036093; NAC_dom_sf.
DR Pfam; PF02365; NAM; 1.
DR SUPFAM; SSF101941; SSF101941; 1.
DR PROSITE; PS51005; NAC; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..323
FT /note="NAC transcription factor 25"
FT /id="PRO_0000420370"
FT DOMAIN 16..177
FT /note="NAC"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00353"
FT DNA_BIND 114..183
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00353"
FT REGION 201..223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 39
FT /note="D -> A (in Ref. 4; AAM65392)"
FT /evidence="ECO:0000305"
FT CONFLICT 223
FT /note="E -> K (in Ref. 4; AAM65392)"
FT /evidence="ECO:0000305"
FT CONFLICT 247
FT /note="H -> D (in Ref. 4; AAM65392)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 323 AA; 36313 MW; 4F029B07A06801AC CRC64;
MENMGDSSIG PGHPHLPPGF RFHPTDEELV VHYLKKKADS VPLPVSIIAE IDLYKFDPWE
LPSKASFGEH EWYFFSPRDR KYPNGVRPNR AATSGYWKAT GTDKPIFTCN SHKVGVKKAL
VFYGGKPPKG IKTDWIMHEY RLTDGNLSTA AKPPDLTTTR KNSLRLDDWV LCRIYKKNSS
QRPTMERVLL REDLMEGMLS KSSANSSSTS VLDNNDNNNN NNEEHFFDGM VVSSDKRSLC
GQYRMGHEAS GSSSFGSFLS SKRFHHTGDL NNDNYNVSFV SMLSEIPQSS GFHANGVMDT
TSSLADHGVL RQAFQLPNMN WHS
