NAC26_ORYSJ
ID NAC26_ORYSJ Reviewed; 333 AA.
AC Q5VNK1; Q0JMJ5;
DT 02-JUN-2021, integrated into UniProtKB/Swiss-Prot.
DT 02-JUN-2021, sequence version 2.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=NAC domain-containing protein 26 {ECO:0000303|PubMed:15029955};
DE Short=ONAC026 {ECO:0000303|PubMed:15029955};
DE Short=OsNAC26 {ECO:0000303|PubMed:32989010};
GN Name=NAC26 {ECO:0000303|PubMed:15029955}; Synonyms=DLN11 {ECO:0000305};
GN OrderedLocusNames=Os01g0393100 {ECO:0000312|EMBL:BAS72293.1},
GN LOC_Os01g29840 {ECO:0000305};
GN ORFNames=B1109A06.36 {ECO:0000312|EMBL:BAD68974.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
RA Yoon U.H., Kim Y.H.;
RT "Molecular cloning of NAC gene in rice.";
RL Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447438; DOI=10.1038/nature01184;
RA Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y.,
RA Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H.,
RA Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M.,
RA Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M.,
RA Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T.,
RA Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S.,
RA Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H.,
RA Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y.,
RA Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S.,
RA Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y.,
RA Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S.,
RA Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H.,
RA Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.;
RT "The genome sequence and structure of rice chromosome 1.";
RL Nature 420:312-316(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=15029955; DOI=10.1093/dnares/10.6.239;
RA Ooka H., Satoh K., Doi K., Nagata T., Otomo Y., Murakami K., Matsubara K.,
RA Osato N., Kawai J., Carninci P., Hayashizaki Y., Suzuki K., Kojima K.,
RA Takahara Y., Yamamoto K., Kikuchi S.;
RT "Comprehensive analysis of NAC family genes in Oryza sativa and Arabidopsis
RT thaliana.";
RL DNA Res. 10:239-247(2003).
RN [7]
RP TISSUE SPECIFICITY.
RX PubMed=18813954; DOI=10.1007/s00438-008-0386-6;
RA Fang Y., You J., Xie K., Xie W., Xiong L.;
RT "Systematic sequence analysis and identification of tissue-specific or
RT stress-responsive genes of NAC transcription factor family in rice.";
RL Mol. Genet. Genomics 280:547-563(2008).
RN [8]
RP INTERACTION WITH NAC20 AND NAC23, SUBCELLULAR LOCATION, AND TISSUE
RP SPECIFICITY.
RX PubMed=27872632; DOI=10.3389/fpls.2016.01638;
RA Mathew I.E., Das S., Mahto A., Agarwal P.;
RT "Three rice NAC transcription factors heteromerize and are associated with
RT seed size.";
RL Front. Plant Sci. 7:1638-1638(2016).
RN [9]
RP FUNCTION, INTERACTION WITH NAC20, SUBCELLULAR LOCATION, TISSUE SPECIFICITY,
RP AND DISRUPTION PHENOTYPE.
RX PubMed=32989010; DOI=10.1104/pp.20.00984;
RA Wang J., Chen Z., Zhang Q., Meng S., Wei C.;
RT "The NAC transcription factors OsNAC20 and OsNAC26 regulate starch and
RT storage protein synthesis.";
RL Plant Physiol. 184:1775-1791(2020).
CC -!- FUNCTION: Transcription factor that acts redundantly with NAC20 to
CC regulate the expression of genes involved in the biosynthesis of starch
CC and storage proteins in grain (PubMed:32989010). Directly binds to the
CC promoters of starch synthase 1 (SS1), pullulanase (PUL), glutelin A1
CC (GLUA1), glutelins B4 and B5 (GLUB4 and GLUB5), alpha-globulin and 16
CC kDa prolamin, and activates their expression (PubMed:32989010).
CC {ECO:0000269|PubMed:32989010}.
CC -!- SUBUNIT: Forms homodimers (PubMed:32989010). Forms heterodimers with
CC NAC20 (PubMed:27872632, PubMed:32989010). Forms heterodimers with NAC23
CC (PubMed:27872632). {ECO:0000269|PubMed:27872632,
CC ECO:0000269|PubMed:32989010}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00353,
CC ECO:0000269|PubMed:27872632, ECO:0000269|PubMed:32989010}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q5VNK1-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q5VNK1-2; Sequence=VSP_061037;
CC -!- TISSUE SPECIFICITY: Expressed in developing seeds (PubMed:27872632).
CC Expressed in developing endosperm (PubMed:18813954, PubMed:32989010).
CC {ECO:0000269|PubMed:18813954, ECO:0000269|PubMed:27872632,
CC ECO:0000269|PubMed:32989010}.
CC -!- DOMAIN: The NAC domain includes a DNA binding domain and a dimerization
CC domain. {ECO:0000255|PROSITE-ProRule:PRU00353}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype under normal growth
CC conditions (PubMed:32989010). The double mutant nac20 and nac26 exhibit
CC a floury grain phenotype due to decreased starch and storage protein
CC content (PubMed:32989010). {ECO:0000269|PubMed:32989010}.
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DR EMBL; EU846995; ACJ54899.1; -; mRNA.
DR EMBL; AP004610; BAD68974.1; -; Genomic_DNA.
DR EMBL; AP008207; BAF05033.1; -; Genomic_DNA.
DR EMBL; AP014957; BAS72293.1; -; Genomic_DNA.
DR RefSeq; XP_015629856.1; XM_015774370.1. [Q5VNK1-1]
DR AlphaFoldDB; Q5VNK1; -.
DR SMR; Q5VNK1; -.
DR STRING; 4530.OS01T0393100-01; -.
DR PaxDb; Q5VNK1; -.
DR PRIDE; Q5VNK1; -.
DR EnsemblPlants; Os01t0393100-01; Os01t0393100-01; Os01g0393100. [Q5VNK1-2]
DR GeneID; 4324532; -.
DR Gramene; Os01t0393100-01; Os01t0393100-01; Os01g0393100. [Q5VNK1-2]
DR KEGG; osa:4324532; -.
DR eggNOG; ENOG502QSPY; Eukaryota.
DR HOGENOM; CLU_035664_6_0_1; -.
DR InParanoid; Q5VNK1; -.
DR OMA; MIGEKEW; -.
DR Proteomes; UP000000763; Chromosome 1.
DR Proteomes; UP000059680; Chromosome 1.
DR GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR GO; GO:2000014; P:regulation of endosperm development; IDA:UniProtKB.
DR Gene3D; 2.170.150.80; -; 1.
DR InterPro; IPR003441; NAC-dom.
DR InterPro; IPR036093; NAC_dom_sf.
DR Pfam; PF02365; NAM; 1.
DR SUPFAM; SSF101941; SSF101941; 1.
DR PROSITE; PS51005; NAC; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; DNA-binding; Nucleus; Reference proteome;
KW Transcription; Transcription regulation.
FT CHAIN 1..333
FT /note="NAC domain-containing protein 26"
FT /id="PRO_0000452674"
FT DOMAIN 14..173
FT /note="NAC"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00353"
FT DNA_BIND 114..179
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00353"
FT REGION 143..162
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 145..159
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 309..333
FT /note="DAADQNNAADISSVACNMDATIWKY -> ATWTLPSGSTDTYIHTYIHT
FT (in isoform 2)"
FT /evidence="ECO:0000305"
FT /id="VSP_061037"
SQ SEQUENCE 333 AA; 37383 MW; 745F149E31F1DD5B CRC64;
MGEQQQQVER QPDLPPGFRF HPTDEEIITF YLAPKVVDSR GFCVAAIGEV DLNKCEPWDL
PGKAKMNGEK EWYFYCQKDR KYPTGMRTNR ATEAGYWKAT GKDKEIFRNH HMLIGMKKTL
VFYKGRAPKG DKTNWVMHEY RLADASPPQP PPPPSSAEPP RQDDWAVCRI FHKSSGIKKP
VQVPMQMPMQ MQMPVAHQVP AANYQQQMAM ASASIIQVPM QMQMPSMSDQ LQMLDDFSTG
SLMAPPPPPP SYSTLPGFPL QINGGAQQFV GNPSMYYQQQ QQQQQQQMDM AAGGFVVSEP
SSLVVSPQDA ADQNNAADIS SVACNMDATI WKY
