ID   NAC2_ARATH              Reviewed;         289 AA.
AC   Q39013; Q9LQ85;
DT   16-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 2.
DT   03-AUG-2022, entry version 127.
DE   RecName: Full=NAC domain-containing protein 2;
DE            Short=ANAC002;
GN   Name=NAC002; Synonyms=ATAF1; OrderedLocusNames=At1g01720; ORFNames=T1N6.12;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Rueth J., Schweyen R., Hirt H.;
RL   Submitted (AUG-1993) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [5]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=15029955; DOI=10.1093/dnares/10.6.239;
RA   Ooka H., Satoh K., Doi K., Nagata T., Otomo Y., Murakami K., Matsubara K.,
RA   Osato N., Kawai J., Carninci P., Hayashizaki Y., Suzuki K., Kojima K.,
RA   Takahara Y., Yamamoto K., Kikuchi S.;
RT   "Comprehensive analysis of NAC family genes in Oryza sativa and Arabidopsis
RT   thaliana.";
RL   DNA Res. 10:239-247(2003).
RN   [6]
RP   INTERACTION WITH KIN10 AND KIN11.
RX   DOI=10.1016/j.plantsci.2009.06.011;
RA   Kleinow T., Himbert S., Krenz B., Jeske H., Koncz C.;
RT   "NAC domain transcription factor ATAF1 interacts with SNF1-related kinases
RT   and silencing of its subfamily causes severe developmental defects in
RT   Arabidopsis.";
RL   Plant Sci. 177:360-370(2009).
CC   -!- SUBUNIT: Interacts with KIN10 and KIN11. {ECO:0000269|Ref.6}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00353}.
CC   -!- DOMAIN: The NAC domain includes a DNA-binding domain and a dimerization
CC       domain.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAA52771.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; X74755; CAA52771.1; ALT_INIT; mRNA.
DR   EMBL; AC009273; AAF78403.1; -; Genomic_DNA.
DR   EMBL; CP002684; AEE27326.1; -; Genomic_DNA.
DR   EMBL; AF370617; AAK43936.1; -; mRNA.
DR   PIR; E86148; E86148.
DR   PIR; S37101; S37101.
DR   RefSeq; NP_171677.1; NM_100054.3.
DR   AlphaFoldDB; Q39013; -.
DR   SMR; Q39013; -.
DR   BioGRID; 24500; 10.
DR   STRING; 3702.AT1G01720.1; -.
DR   PaxDb; Q39013; -.
DR   PRIDE; Q39013; -.
DR   ProteomicsDB; 251077; -.
DR   EnsemblPlants; AT1G01720.1; AT1G01720.1; AT1G01720.
DR   GeneID; 839265; -.
DR   Gramene; AT1G01720.1; AT1G01720.1; AT1G01720.
DR   KEGG; ath:AT1G01720; -.
DR   Araport; AT1G01720; -.
DR   TAIR; locus:2198225; AT1G01720.
DR   eggNOG; ENOG502QVRF; Eukaryota.
DR   HOGENOM; CLU_035664_3_1_1; -.
DR   InParanoid; Q39013; -.
DR   OMA; TDWEKAT; -.
DR   OrthoDB; 977765at2759; -.
DR   PhylomeDB; Q39013; -.
DR   PRO; PR:Q39013; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; Q39013; baseline and differential.
DR   Genevisible; Q39013; AT.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR   GO; GO:0019900; F:kinase binding; IPI:UniProtKB.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR   GO; GO:0071456; P:cellular response to hypoxia; HEP:TAIR.
DR   GO; GO:0009788; P:negative regulation of abscisic acid-activated signaling pathway; IMP:TAIR.
DR   GO; GO:0009611; P:response to wounding; IEP:TAIR.
DR   Gene3D; 2.170.150.80; -; 1.
DR   InterPro; IPR003441; NAC-dom.
DR   InterPro; IPR036093; NAC_dom_sf.
DR   Pfam; PF02365; NAM; 1.
DR   SUPFAM; SSF101941; SSF101941; 1.
DR   PROSITE; PS51005; NAC; 1.
PE   1: Evidence at protein level;
KW   DNA-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..289
FT                   /note="NAC domain-containing protein 2"
FT                   /id="PRO_0000132306"
FT   DOMAIN          7..158
FT                   /note="NAC"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00353"
SQ   SEQUENCE   289 AA;  32922 MW;  DDAC62A101B6CE4B CRC64;
     MSELLQLPPG FRFHPTDEEL VMHYLCRKCA SQSIAVPIIA EIDLYKYDPW ELPGLALYGE
     KEWYFFSPRD RKYPNGSRPN RSAGSGYWKA TGADKPIGLP KPVGIKKALV FYAGKAPKGE
     KTNWIMHEYR LADVDRSVRK KKNSLRLDDW VLCRIYNKKG ATERRGPPPP VVYGDEIMEE
     KPKVTEMVMP PPPQQTSEFA YFDTSDSVPK LHTTDSSCSE QVVSPEFTSE VQSEPKWKDW
     SAVSNDNNNT LDFGFNYIDA TVDNAFGGGG SSNQMFPLQD MFMYMQKPY