NAC2_ORYSJ
ID NAC2_ORYSJ Reviewed; 316 AA.
AC Q75HE5; Q27JE5;
DT 20-DEC-2017, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 131.
DE RecName: Full=NAC domain-containing protein 2 {ECO:0000303|PubMed:15029955};
DE Short=ONAC002 {ECO:0000303|PubMed:15029955};
DE AltName: Full=OsNAC19 {ECO:0000303|Ref.1};
DE AltName: Full=Protein STRESS-RESPONSIVE NAC 1 {ECO:0000303|PubMed:16924117};
GN Name=NAC002 {ECO:0000303|PubMed:15029955};
GN Synonyms=NAC19 {ECO:0000303|Ref.1}, SNAC1 {ECO:0000303|PubMed:16924117};
GN OrderedLocusNames=Os03g0815100 {ECO:0000312|EMBL:BAF13596.1},
GN LOC_Os03g60080 {ECO:0000312|EMBL:ABF99536.1};
GN ORFNames=OsJ_13092 {ECO:0000312|EMBL:EAZ29041.1},
GN OSJNBa0024F18.3 {ECO:0000312|EMBL:AAR89838.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX AGRICOLA=IND43855822;
RA Lin R., Zhao W., Meng X., Wang M., Peng Y.;
RT "Rice gene OsNAC19 encodes a novel NAC-domain transcription factor and
RT responds to infection by Magnaporthe grisea.";
RL Plant Sci. 172:120-130(2007).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16109971; DOI=10.1101/gr.3869505;
RG The rice chromosome 3 sequencing consortium;
RA Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B.,
RA Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T.,
RA Fadrosh D., Bera J., Weaver B., Jin S., Johri S., Reardon M., Webb K.,
RA Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T.,
RA Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R.,
RA Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J.,
RA Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S.,
RA Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M.,
RA Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M.,
RA Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L.,
RA O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R.,
RA Jin W., Lee H.R., Jiang J., Jackson S.;
RT "Sequence, annotation, and analysis of synteny between rice chromosome 3
RT and diverged grass species.";
RL Genome Res. 15:1284-1291(2005).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [7]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [8]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 3-316, FUNCTION, SUBCELLULAR LOCATION, TISSUE
RP SPECIFICITY, AND INDUCTION.
RX PubMed=16924117; DOI=10.1073/pnas.0604882103;
RA Hu H., Dai M., Yao J., Xiao B., Li X., Zhang Q., Xiong L.;
RT "Overexpressing a NAM, ATAF, and CUC (NAC) transcription factor enhances
RT drought resistance and salt tolerance in rice.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:12987-12992(2006).
RN [9]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=15029955; DOI=10.1093/dnares/10.6.239;
RA Ooka H., Satoh K., Doi K., Nagata T., Otomo Y., Murakami K., Matsubara K.,
RA Osato N., Kawai J., Carninci P., Hayashizaki Y., Suzuki K., Kojima K.,
RA Takahara Y., Yamamoto K., Kikuchi S.;
RT "Comprehensive analysis of NAC family genes in Oryza sativa and Arabidopsis
RT thaliana.";
RL DNA Res. 10:239-247(2003).
RN [10]
RP FUNCTION, INTERACTION WITH NAC071, AND INDUCTION.
RX PubMed=20632034; DOI=10.1007/s00438-010-0557-0;
RA Takasaki H., Maruyama K., Kidokoro S., Ito Y., Fujita Y., Shinozaki K.,
RA Yamaguchi-Shinozaki K., Nakashima K.;
RT "The abiotic stress-responsive NAC-type transcription factor OsNAC5
RT regulates stress-inducible genes and stress tolerance in rice.";
RL Mol. Genet. Genomics 284:173-183(2010).
RN [11]
RP X-RAY CRYSTALLOGRAPHY (2.60 ANGSTROMS) OF 3-176, AND HOMODIMER.
RX PubMed=21337010; DOI=10.1007/s13238-011-1010-9;
RA Chen Q., Wang Q., Xiong L., Lou Z.;
RT "A structural view of the conserved domain of rice stress-responsive
RT NAC1.";
RL Protein Cell 2:55-63(2011).
CC -!- FUNCTION: Transcription factor that possesses transactivation activity
CC (PubMed:16924117, PubMed:20632034). Transcription activator involved in
CC response to abiotic stresses. Plays a positive role during dehydration
CC and salt stress. Binds specifically to the 5'-CATGTG-3' motif found in
CC promoters of stress-responsive genes (PubMed:16924117).
CC {ECO:0000269|PubMed:16924117, ECO:0000269|PubMed:20632034}.
CC -!- SUBUNIT: Forms homodimer (PubMed:21337010). Interacts with NAC071
CC (PubMed:20632034). {ECO:0000269|PubMed:20632034,
CC ECO:0000269|PubMed:21337010}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00353,
CC ECO:0000269|PubMed:16924117}.
CC -!- TISSUE SPECIFICITY: Expressed in roots and stamens.
CC {ECO:0000269|PubMed:16924117}.
CC -!- INDUCTION: Induced by drought stress, salt stress and cold stress
CC (PubMed:16924117, PubMed:20632034). Induced by abscisic acid (ABA)
CC (PubMed:16924117). Induced by methyl jasmonate (PubMed:20632034).
CC {ECO:0000269|PubMed:16924117, ECO:0000269|PubMed:20632034}.
CC -!- DOMAIN: The NAC domain includes a DNA binding domain and a dimerization
CC domain. {ECO:0000255|PROSITE-ProRule:PRU00353}.
CC -!- MISCELLANEOUS: Plants overexpressing NAC002 exhibit improved tolerance
CC to drought and salt stresses. {ECO:0000269|PubMed:16924117}.
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DR EMBL; AY596808; AAT02360.1; -; mRNA.
DR EMBL; AC135594; AAR89838.1; -; Genomic_DNA.
DR EMBL; DP000009; ABF99536.1; -; Genomic_DNA.
DR EMBL; AP008209; BAF13596.1; -; Genomic_DNA.
DR EMBL; AP014959; BAS87028.1; -; Genomic_DNA.
DR EMBL; CM000140; EAZ29041.1; -; Genomic_DNA.
DR EMBL; AK067690; BAG90542.1; -; mRNA.
DR EMBL; AK099245; BAG94018.1; -; mRNA.
DR EMBL; AK104551; BAG96778.1; -; mRNA.
DR EMBL; AK104712; BAG96896.1; -; mRNA.
DR EMBL; DQ394702; ABD52007.1; -; mRNA.
DR RefSeq; XP_015630558.1; XM_015775072.1.
DR PDB; 3ULX; X-ray; 2.60 A; A=3-176.
DR PDBsum; 3ULX; -.
DR AlphaFoldDB; Q75HE5; -.
DR SMR; Q75HE5; -.
DR STRING; 4530.OS03T0815100-01; -.
DR PaxDb; Q75HE5; -.
DR PRIDE; Q75HE5; -.
DR EnsemblPlants; Os03t0815100-01; Os03t0815100-01; Os03g0815100.
DR GeneID; 4334553; -.
DR Gramene; Os03t0815100-01; Os03t0815100-01; Os03g0815100.
DR KEGG; osa:4334553; -.
DR eggNOG; ENOG502QRBC; Eukaryota.
DR HOGENOM; CLU_035664_5_2_1; -.
DR InParanoid; Q75HE5; -.
DR OMA; RTHSWGE; -.
DR OrthoDB; 697995at2759; -.
DR PlantReactome; R-OSA-9627499; SNAC1 transcription network involved in drought and salinity tolerance.
DR Proteomes; UP000000763; Chromosome 3.
DR Proteomes; UP000007752; Chromosome 3.
DR Proteomes; UP000059680; Chromosome 3.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR GO; GO:1901002; P:positive regulation of response to salt stress; IMP:UniProtKB.
DR GO; GO:1902584; P:positive regulation of response to water deprivation; IMP:UniProtKB.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR Gene3D; 2.170.150.80; -; 1.
DR InterPro; IPR003441; NAC-dom.
DR InterPro; IPR036093; NAC_dom_sf.
DR Pfam; PF02365; NAM; 1.
DR SUPFAM; SSF101941; SSF101941; 1.
DR PROSITE; PS51005; NAC; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Activator; DNA-binding; Nucleus; Reference proteome;
KW Stress response; Transcription; Transcription regulation.
FT CHAIN 1..316
FT /note="NAC domain-containing protein 2"
FT /id="PRO_0000442723"
FT DOMAIN 17..170
FT /note="NAC"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00353"
FT DNA_BIND 114..176
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00353"
FT REGION 185..210
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT TURN 14..16
FT /evidence="ECO:0007829|PDB:3ULX"
FT HELIX 27..33
FT /evidence="ECO:0007829|PDB:3ULX"
FT HELIX 35..39
FT /evidence="ECO:0007829|PDB:3ULX"
FT STRAND 45..47
FT /evidence="ECO:0007829|PDB:3ULX"
FT HELIX 54..56
FT /evidence="ECO:0007829|PDB:3ULX"
FT HELIX 59..61
FT /evidence="ECO:0007829|PDB:3ULX"
FT HELIX 63..65
FT /evidence="ECO:0007829|PDB:3ULX"
FT STRAND 70..78
FT /evidence="ECO:0007829|PDB:3ULX"
FT STRAND 91..93
FT /evidence="ECO:0007829|PDB:3ULX"
FT STRAND 96..100
FT /evidence="ECO:0007829|PDB:3ULX"
FT STRAND 105..107
FT /evidence="ECO:0007829|PDB:3ULX"
FT STRAND 110..112
FT /evidence="ECO:0007829|PDB:3ULX"
FT STRAND 115..126
FT /evidence="ECO:0007829|PDB:3ULX"
FT STRAND 131..142
FT /evidence="ECO:0007829|PDB:3ULX"
FT STRAND 160..170
FT /evidence="ECO:0007829|PDB:3ULX"
SQ SEQUENCE 316 AA; 35178 MW; EA6FEBE9849B8CC8 CRC64;
MGMGMRRERD AEAELNLPPG FRFHPTDDEL VEHYLCRKAA GQRLPVPIIA EVDLYKFDPW
DLPERALFGA REWYFFTPRD RKYPNGSRPN RAAGNGYWKA TGADKPVAPR GRTLGIKKAL
VFYAGKAPRG VKTDWIMHEY RLADAGRAAA GAKKGSLRLD DWVLCRLYNK KNEWEKMQQG
KEVKEEASDM VTSQSHSHTH SWGETRTPES EIVDNDPFPE LDSFPAFQPA PPPATAMMVP
KKESMDDATA AAAAAATIPR NNSSLFVDLS YDDIQGMYSG LDMLPPGDDF YSSLFASPRV
KGTTPRAGAG MGMVPF
