NAC37_ARATH
ID NAC37_ARATH Reviewed; 365 AA.
AC Q9SL41;
DT 27-MAY-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 25-MAY-2022, entry version 120.
DE RecName: Full=NAC domain-containing protein 37 {ECO:0000303|PubMed:15029955};
DE Short=ANAC037 {ECO:0000303|PubMed:15029955};
DE AltName: Full=Protein VASCULAR RELATED NAC-DOMAIN 1 {ECO:0000303|PubMed:16103214};
GN Name=NAC037 {ECO:0000303|PubMed:15029955};
GN Synonyms=VND1 {ECO:0000303|PubMed:16103214};
GN OrderedLocusNames=At2g18060 {ECO:0000312|Araport:AT2G18060};
GN ORFNames=T27K22.7 {ECO:0000312|EMBL:AAD20120.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|Proteomes:UP000006548};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=15029955; DOI=10.1093/dnares/10.6.239;
RA Ooka H., Satoh K., Doi K., Nagata T., Otomo Y., Murakami K., Matsubara K.,
RA Osato N., Kawai J., Carninci P., Hayashizaki Y., Suzuki K., Kojima K.,
RA Takahara Y., Yamamoto K., Kikuchi S.;
RT "Comprehensive analysis of NAC family genes in Oryza sativa and Arabidopsis
RT thaliana.";
RL DNA Res. 10:239-247(2003).
RN [4]
RP DEVELOPMENTAL STAGE, TISSUE SPECIFICITY, GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16103214; DOI=10.1101/gad.1331305;
RA Kubo M., Udagawa M., Nishikubo N., Horiguchi G., Yamaguchi M., Ito J.,
RA Mimura T., Fukuda H., Demura T.;
RT "Transcription switches for protoxylem and metaxylem vessel formation.";
RL Genes Dev. 19:1855-1860(2005).
RN [5]
RP INDUCTION BY CHITIN.
RX PubMed=17722694; DOI=10.1094/mpmi-20-8-0900;
RA Libault M., Wan J., Czechowski T., Udvardi M., Stacey G.;
RT "Identification of 118 Arabidopsis transcription factor and 30 ubiquitin-
RT ligase genes responding to chitin, a plant-defense elicitor.";
RL Mol. Plant Microbe Interact. 20:900-911(2007).
RN [6]
RP INDUCTION BY CALLUS INDUCTION MEDIUM.
RX PubMed=17581762; DOI=10.1007/s00425-007-0565-4;
RA Che P., Lall S., Howell S.H.;
RT "Developmental steps in acquiring competence for shoot development in
RT Arabidopsis tissue culture.";
RL Planta 226:1183-1194(2007).
RN [7]
RP TISSUE SPECIFICITY, AND INTERACTION WITH NAC030/VND7.
RC STRAIN=cv. Columbia;
RX PubMed=18445131; DOI=10.1111/j.1365-313x.2008.03533.x;
RA Yamaguchi M., Kubo M., Fukuda H., Demura T.;
RT "Vascular-related NAC-DOMAIN7 is involved in the differentiation of all
RT types of xylem vessels in Arabidopsis roots and shoots.";
RL Plant J. 55:652-664(2008).
RN [8]
RP FUNCTION, TISSUE SPECIFICITY, AND DEVELOPMENTAL STAGE.
RX PubMed=25148240; DOI=10.1371/journal.pone.0105726;
RA Zhou J., Zhong R., Ye Z.-H.;
RT "Arabidopsis NAC domain proteins, VND1 to VND5, are transcriptional
RT regulators of secondary wall biosynthesis in vessels.";
RL PLoS ONE 9:E105726-E105726(2014).
CC -!- FUNCTION: Transcription activator that binds to the secondary wall NAC
CC binding element (SNBE), 5'-
CC (T/A)NN(C/T)(T/C/G)TNNNNNNNA(A/C)GN(A/C/T)(A/T)-3', in the promoter of
CC target genes (By similarity). Involved in xylem formation by promoting
CC the expression of secondary wall-associated transcription factors and
CC of genes involved in secondary wall biosynthesis and programmed cell
CC death, genes driven by the secondary wall NAC binding element (SNBE).
CC Triggers thickening of secondary walls (PubMed:25148240).
CC {ECO:0000250|UniProtKB:Q9LVA1, ECO:0000269|PubMed:25148240}.
CC -!- SUBUNIT: Interacts with NAC030/VND7. {ECO:0000269|PubMed:16103214,
CC ECO:0000269|PubMed:18445131}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9C8W9,
CC ECO:0000255|PROSITE-ProRule:PRU00353}.
CC -!- TISSUE SPECIFICITY: Expressed in root metaxylem pole and in shoot pre-
CC procambium and procambium (PubMed:18445131). Present in root developing
CC xylems (PubMed:16103214). Specifically expressed in vessels but not in
CC interfascicular fibers in stems (PubMed:25148240).
CC {ECO:0000269|PubMed:16103214, ECO:0000269|PubMed:18445131,
CC ECO:0000269|PubMed:25148240}.
CC -!- DEVELOPMENTAL STAGE: Up-regulated during xylem vessel element
CC formation. Expressed preferentially in procambial cells adjacent to
CC root meristem. {ECO:0000269|PubMed:16103214,
CC ECO:0000269|PubMed:25148240}.
CC -!- INDUCTION: Induced by chitin (e.g. chitooctaose) (PubMed:17722694).
CC Accumulates in plants exposed to callus induction medium (CIM)
CC (PubMed:17581762). {ECO:0000269|PubMed:17581762,
CC ECO:0000269|PubMed:17722694}.
CC -!- DOMAIN: The NAC domain includes a DNA binding domain and a dimerization
CC domain. {ECO:0000255|PROSITE-ProRule:PRU00353}.
CC -!- SIMILARITY: Belongs to the plant vascular related NAC-domain protein
CC family. {ECO:0000305}.
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DR EMBL; AC006201; AAD20120.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC06722.1; -; Genomic_DNA.
DR EMBL; CP002685; ANM61740.1; -; Genomic_DNA.
DR PIR; G84559; G84559.
DR RefSeq; NP_001318244.1; NM_001335579.1.
DR RefSeq; NP_179397.1; NM_127362.2.
DR AlphaFoldDB; Q9SL41; -.
DR SMR; Q9SL41; -.
DR IntAct; Q9SL41; 1.
DR STRING; 3702.AT2G18060.1; -.
DR PaxDb; Q9SL41; -.
DR PRIDE; Q9SL41; -.
DR ProteomicsDB; 251192; -.
DR EnsemblPlants; AT2G18060.1; AT2G18060.1; AT2G18060.
DR EnsemblPlants; AT2G18060.3; AT2G18060.3; AT2G18060.
DR GeneID; 816318; -.
DR Gramene; AT2G18060.1; AT2G18060.1; AT2G18060.
DR Gramene; AT2G18060.3; AT2G18060.3; AT2G18060.
DR KEGG; ath:AT2G18060; -.
DR Araport; AT2G18060; -.
DR TAIR; locus:2060979; AT2G18060.
DR eggNOG; ENOG502QQGU; Eukaryota.
DR HOGENOM; CLU_035664_1_2_1; -.
DR InParanoid; Q9SL41; -.
DR OMA; MESCSVP; -.
DR OrthoDB; 825417at2759; -.
DR PhylomeDB; Q9SL41; -.
DR PRO; PR:Q9SL41; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9SL41; baseline and differential.
DR Genevisible; Q9SL41; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:UniProtKB.
DR GO; GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:1990110; P:callus formation; IEP:UniProtKB.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR GO; GO:1901348; P:positive regulation of secondary cell wall biogenesis; IMP:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IMP:TAIR.
DR GO; GO:0048759; P:xylem vessel member cell differentiation; IMP:TAIR.
DR Gene3D; 2.170.150.80; -; 1.
DR InterPro; IPR003441; NAC-dom.
DR InterPro; IPR036093; NAC_dom_sf.
DR Pfam; PF02365; NAM; 1.
DR SUPFAM; SSF101941; SSF101941; 1.
DR PROSITE; PS51005; NAC; 1.
PE 1: Evidence at protein level;
KW Activator; Cell wall biogenesis/degradation; Developmental protein;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..365
FT /note="NAC domain-containing protein 37"
FT /id="PRO_0000433121"
FT DOMAIN 9..158
FT /note="NAC"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00353"
FT DNA_BIND 109..164
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00353"
SQ SEQUENCE 365 AA; 42477 MW; 03F777BAC7C4E9BA CRC64;
MEPMESCSVP PGFRFHPTDE ELVGYYLRKK IASQKIDLDV IRDIDLYRIE PWDLQEQCRI
GYEEQNEWYF FSHKDKKYPT GTRTNRATMA GFWKATGRDK AVYDKTKLIG MRKTLVFYKG
RAPNGKKSDW IMHEYRLESD ENAPPQEEGW VVCRAFKKRA TGQAKNTETW SSSYFYDEVA
PNGVNSVMDP IDYISKQQHN IFGKGLMCKQ ELEGMVDGIN YIQSNQFIQL PQLQSPSLPL
MKRPSSSMSI TSMDNNYNYK LPLADEESFE SFIRGEDRRK KKKQVMMTGN WRELDKFVAS
QLMSQEDNGT SSFAGHHIVN EDKNNNDVEM DSSMFLSERE EENRFVSEFL STNSDYDIGI
CVFDN
