NAC6_SOYBN
ID NAC6_SOYBN Reviewed; 297 AA.
AC I1LPE9; C6TLR1; Q52QR0;
DT 07-OCT-2020, integrated into UniProtKB/Swiss-Prot.
DT 13-JUN-2012, sequence version 1.
DT 03-AUG-2022, entry version 58.
DE RecName: Full=NAC domain-containing protein 6 {ECO:0000303|PubMed:16919368};
DE Short=GmNAC6 {ECO:0000303|PubMed:16919368};
GN Name=NAC6 {ECO:0000303|PubMed:16919368};
GN ORFNames=GLYMA_12G022700 {ECO:0000312|EMBL:KRH24118.1};
OS Glycine max (Soybean) (Glycine hispida).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC Glycine subgen. Soja.
OX NCBI_TaxID=3847;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], TISSUE SPECIFICITY, AND
RP DEVELOPMENTAL STAGE.
RX PubMed=16919368; DOI=10.1016/j.jplph.2006.05.019;
RA Meng Q., Zhang C., Gai J., Yu D.;
RT "Molecular cloning, sequence characterization and tissue-specific
RT expression of six NAC-like genes in soybean (Glycine max (L.) Merr.).";
RL J. Plant Physiol. 164:1002-1012(2007).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Williams 82;
RX PubMed=20075913; DOI=10.1038/nature08670;
RA Schmutz J., Cannon S.B., Schlueter J., Ma J., Mitros T., Nelson W.,
RA Hyten D.L., Song Q., Thelen J.J., Cheng J., Xu D., Hellsten U., May G.D.,
RA Yu Y., Sakurai T., Umezawa T., Bhattacharyya M.K., Sandhu D.,
RA Valliyodan B., Lindquist E., Peto M., Grant D., Shu S., Goodstein D.,
RA Barry K., Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N.,
RA Joshi T., Libault M., Sethuraman A., Zhang X.-C., Shinozaki K.,
RA Nguyen H.T., Wing R.A., Cregan P., Specht J., Grimwood J., Rokhsar D.,
RA Stacey G., Shoemaker R.C., Jackson S.A.;
RT "Genome sequence of the palaeopolyploid soybean.";
RL Nature 463:178-183(2010).
RN [3]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 1-201.
RA Cheung F., Xiao Y., Chan A., Moskal W., Town C.D.;
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP FUNCTION, SUBCELLULAR LOCATION, AND INDUCTION BY ABSCISIC ACID.
RX PubMed=19497355; DOI=10.1016/j.gene.2009.05.012;
RA Pinheiro G.L., Marques C.S., Costa M.D., Reis P.A., Alves M.S.,
RA Carvalho C.M., Fietto L.G., Fontes E.P.;
RT "Complete inventory of soybean NAC transcription factors: sequence
RT conservation and expression analysis uncover their distinct roles in stress
RT response.";
RL Gene 444:10-23(2009).
RN [5]
RP FUNCTION, AND INDUCTION.
RX PubMed=21943253; DOI=10.1186/1471-2229-11-129;
RA Faria J.A., Reis P.A., Reis M.T., Rosado G.L., Pinheiro G.L., Mendes G.C.,
RA Fontes E.P.;
RT "The NAC domain-containing protein, GmNAC6, is a downstream component of
RT the ER stress- and osmotic stress-induced NRP-mediated cell-death signaling
RT pathway.";
RL BMC Plant Biol. 11:129-129(2011).
CC -!- FUNCTION: Involved in response to abiotic stresses and promotes cell
CC death and hypersensitive-like responses (PubMed:19497355,
CC PubMed:21943253). May act downstream of NRP-A and NRP-B in the
CC endoplasmic reticulum (ER) stress and osmotic stress response that
CC mediates cell death (PubMed:21943253). {ECO:0000269|PubMed:19497355,
CC ECO:0000269|PubMed:21943253}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00353,
CC ECO:0000269|PubMed:19497355}.
CC -!- TISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:16919368}.
CC -!- DEVELOPMENTAL STAGE: Expressed in developing seeds from 15 days after
CC flowering (DAF) to 45 DAF. {ECO:0000269|PubMed:16919368}.
CC -!- INDUCTION: Induced by abscisic acid (ABA) and cycloheximide
CC (PubMed:19497355). Induced by tunicamycin, azetidine-2-carboxylate
CC (AZC) and osmotic stress (PubMed:21943253).
CC {ECO:0000269|PubMed:19497355, ECO:0000269|PubMed:21943253}.
CC -!- DOMAIN: The NAC domain includes a DNA binding domain and a dimerization
CC domain. {ECO:0000255|PROSITE-ProRule:PRU00353}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAX85983.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC Sequence=AAY46126.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AY974354; AAX85983.1; ALT_INIT; Genomic_DNA.
DR EMBL; DQ028774; AAY46126.1; ALT_INIT; mRNA.
DR EMBL; CM000845; KRH24118.1; -; Genomic_DNA.
DR EMBL; BT098651; ACU23853.1; -; mRNA.
DR RefSeq; NP_001236900.2; NM_001249971.3.
DR AlphaFoldDB; I1LPE9; -.
DR SMR; I1LPE9; -.
DR STRING; 3847.GLYMA12G02540.1; -.
DR PRIDE; I1LPE9; -.
DR EnsemblPlants; KRH24118; KRH24118; GLYMA_12G022700.
DR GeneID; 732555; -.
DR Gramene; KRH24118; KRH24118; GLYMA_12G022700.
DR KEGG; gmx:732555; -.
DR eggNOG; ENOG502QUZY; Eukaryota.
DR HOGENOM; CLU_035664_7_0_1; -.
DR InParanoid; I1LPE9; -.
DR OMA; TKEKSNC; -.
DR OrthoDB; 1267713at2759; -.
DR Proteomes; UP000008827; Chromosome 12.
DR ExpressionAtlas; I1LPE9; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR Gene3D; 2.170.150.80; -; 1.
DR InterPro; IPR003441; NAC-dom.
DR InterPro; IPR036093; NAC_dom_sf.
DR Pfam; PF02365; NAM; 1.
DR SUPFAM; SSF101941; SSF101941; 1.
DR PROSITE; PS51005; NAC; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Nucleus; Reference proteome; Stress response; Transcription;
KW Transcription regulation.
FT CHAIN 1..297
FT /note="NAC domain-containing protein 6"
FT /id="PRO_0000451108"
FT DOMAIN 15..161
FT /note="NAC"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00353"
FT DNA_BIND 115..167
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00353"
FT REGION 178..204
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 185..204
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 297 AA; 34335 MW; 0F0D6652B4981BCB CRC64;
MATMEDMNNM SGEITLPGFR FHPTEEELLD FYLKNMVVGK KLRYDVIGFL NIYQHDPWDL
PGLAKVGERE WYFFVPRDKK HGSGGRPNRT TEKGFWKATG SDRKIVTLSD PKRIIGLRKT
LVFYQGRAPR GCKTDWVMNE YRLPDNCKLP KEIVLCKIYR KATSLKVLEQ RAALEEEREM
KQMVGSPASP SSTDTMSFSS PQEEQNMPLP LLQHVLKKES ETEDMVVPKQ EKITNQLVLK
DTNKSTCGTS LQMPFGKEKL PDLQLPMLSD WTQDTFWAQL NSPWLQNFTP TNILNFY
