NACA3_ARATH
ID NACA3_ARATH Reviewed; 204 AA.
AC Q6ICZ8; Q9FFY7;
DT 19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=Nascent polypeptide-associated complex subunit alpha-like protein 3;
DE Short=NAC-alpha-like protein 3;
DE AltName: Full=Alpha-NAC-like protein 3;
GN OrderedLocusNames=At5g13850; ORFNames=MAC12.19;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9330910; DOI=10.1093/dnares/4.3.215;
RA Sato S., Kotani H., Nakamura Y., Kaneko T., Asamizu E., Fukami M.,
RA Miyajima N., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. I. Sequence
RT features of the 1.6 Mb regions covered by twenty physically assigned P1
RT clones.";
RL DNA Res. 4:215-230(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Cheuk R.F., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-36, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19376835; DOI=10.1104/pp.109.138677;
RA Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,
RA Grossmann J., Gruissem W., Baginsky S.;
RT "Large-scale Arabidopsis phosphoproteome profiling reveals novel
RT chloroplast kinase substrates and phosphorylation networks.";
RL Plant Physiol. 150:889-903(2009).
CC -!- FUNCTION: May promote appropriate targeting of ribosome-nascent
CC polypeptide complexes. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the NAC-alpha family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB11113.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; AB005230; BAB11113.1; ALT_FRAME; Genomic_DNA.
DR EMBL; CP002688; AED91950.1; -; Genomic_DNA.
DR EMBL; BT014875; AAT41858.1; -; mRNA.
DR RefSeq; NP_196889.4; NM_121388.9.
DR AlphaFoldDB; Q6ICZ8; -.
DR BioGRID; 16509; 10.
DR IntAct; Q6ICZ8; 1.
DR STRING; 3702.AT5G13850.1; -.
DR iPTMnet; Q6ICZ8; -.
DR MetOSite; Q6ICZ8; -.
DR PaxDb; Q6ICZ8; -.
DR PRIDE; Q6ICZ8; -.
DR ProteomicsDB; 251223; -.
DR EnsemblPlants; AT5G13850.1; AT5G13850.1; AT5G13850.
DR GeneID; 831231; -.
DR Gramene; AT5G13850.1; AT5G13850.1; AT5G13850.
DR KEGG; ath:AT5G13850; -.
DR Araport; AT5G13850; -.
DR TAIR; locus:2159093; AT5G13850.
DR eggNOG; KOG2239; Eukaryota.
DR HOGENOM; CLU_057806_3_0_1; -.
DR InParanoid; Q6ICZ8; -.
DR OMA; SDAYIVF; -.
DR OrthoDB; 1331328at2759; -.
DR PhylomeDB; Q6ICZ8; -.
DR PRO; PR:Q6ICZ8; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q6ICZ8; baseline and differential.
DR Genevisible; Q6ICZ8; AT.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; HDA:TAIR.
DR GO; GO:0022626; C:cytosolic ribosome; HDA:TAIR.
DR GO; GO:0005794; C:Golgi apparatus; HDA:TAIR.
DR GO; GO:0005854; C:nascent polypeptide-associated complex; IEA:InterPro.
DR GO; GO:0009506; C:plasmodesma; HDA:TAIR.
DR GO; GO:0009536; C:plastid; HDA:TAIR.
DR GO; GO:0051082; F:unfolded protein binding; IBA:GO_Central.
DR GO; GO:0006612; P:protein targeting to membrane; IBA:GO_Central.
DR Gene3D; 2.20.70.30; -; 1.
DR InterPro; IPR016641; EGD2/NACA.
DR InterPro; IPR044034; NAC-like_UBA.
DR InterPro; IPR038187; NAC_A/B_dom_sf.
DR InterPro; IPR002715; Nas_poly-pep-assoc_cplx_dom.
DR PANTHER; PTHR21713; PTHR21713; 1.
DR Pfam; PF19026; HYPK_UBA; 1.
DR Pfam; PF01849; NAC; 1.
DR PIRSF; PIRSF015901; NAC_alpha; 1.
DR SMART; SM01407; NAC; 1.
DR PROSITE; PS51151; NAC_AB; 1.
PE 1: Evidence at protein level;
KW Phosphoprotein; Protein transport; Reference proteome; Transport.
FT CHAIN 1..204
FT /note="Nascent polypeptide-associated complex subunit
FT alpha-like protein 3"
FT /id="PRO_0000135589"
FT DOMAIN 56..121
FT /note="NAC-A/B"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00507"
FT DOMAIN 159..204
FT /note="UBA"
FT REGION 1..68
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 141..165
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 21..44
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..66
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 36
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:19376835"
SQ SEQUENCE 204 AA; 22057 MW; F535FC70E00F2402 CRC64;
MTAEQKVELA AKLEEQKIDL DKPEVEDDDD NDEDDSEDDD EAEGHDGEAG GRSKQSRSEK
KSRKAMLKLG MKPITGVSRV TVKKSKNILF VISKPDVFKS PASDTYVIFG EAKIEDLSSQ
LQSQAAEQFK APNLSNVISQ GETSSAATAA AVQDDDDEEV DEEGVEPKDI ELVMTQAGVS
KPRAVKALKL ANGDIVSAIM ELTT
