ID   NACA_BABDI              Reviewed;         197 AA.
AC   Q45FF9;
DT   18-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   03-AUG-2022, entry version 41.
DE   RecName: Full=Nascent polypeptide-associated complex subunit alpha;
DE            Short=NAC-alpha;
DE   AltName: Full=Alpha-NAC;
OS   Babesia divergens.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida;
OC   Babesiidae; Babesia.
OX   NCBI_TaxID=32595;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=Rouen 1987;
RX   PubMed=17135542; DOI=10.1196/annals.1373.057;
RA   Figueroa J.V., Precigout E., Carcy B., Gorenflot A.;
RT   "Identification of common antigens in Babesia bovis, B. bigemina, and B.
RT   divergens.";
RL   Ann. N. Y. Acad. Sci. 1081:382-396(2006).
CC   -!- FUNCTION: May promote appropriate targeting of ribosome-nascent
CC       polypeptide complexes. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NAC-alpha family. {ECO:0000305}.
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DR   EMBL; DQ138321; AAZ66308.1; -; mRNA.
DR   AlphaFoldDB; Q45FF9; -.
DR   VEuPathDB; PiroplasmaDB:Bdiv_031930; -.
DR   GO; GO:0005854; C:nascent polypeptide-associated complex; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.20.70.30; -; 1.
DR   InterPro; IPR016641; EGD2/NACA.
DR   InterPro; IPR044034; NAC-like_UBA.
DR   InterPro; IPR038187; NAC_A/B_dom_sf.
DR   InterPro; IPR002715; Nas_poly-pep-assoc_cplx_dom.
DR   PANTHER; PTHR21713; PTHR21713; 1.
DR   Pfam; PF19026; HYPK_UBA; 1.
DR   Pfam; PF01849; NAC; 1.
DR   PIRSF; PIRSF015901; NAC_alpha; 1.
DR   SMART; SM01407; NAC; 1.
DR   PROSITE; PS51151; NAC_AB; 1.
PE   2: Evidence at transcript level;
KW   Protein transport; Transport.
FT   CHAIN           1..197
FT                   /note="Nascent polypeptide-associated complex subunit
FT                   alpha"
FT                   /id="PRO_0000232706"
FT   DOMAIN          36..101
FT                   /note="NAC-A/B"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00507"
FT   DOMAIN          158..195
FT                   /note="UBA"
FT   REGION          1..46
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          120..154
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..17
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        18..46
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        133..151
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   197 AA;  21150 MW;  0A21069D84099F75 CRC64;
     MAEPVEDSVD EISSEGDSDV EESKGPEGSA PKNRQDKNER KSRKLLGKLG MKPVDGVTKV
     CIKKSKQIYF VVNKPDVYKL PNSDTYVIFG EAKVEDMSQN SALEAAQRLS QLSSALQAVG
     ADRGTDSSAA AHASGHDHAH DHDHSHGDCA SKADESSVNQ SDIDLVVSQV GCTREQAVEA
     LIKNKGDIVE TIMQLST