ID   NACP4_HUMAN             Reviewed;         213 AA.
AC   Q9BZK3;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   25-MAY-2022, entry version 115.
DE   RecName: Full=Putative nascent polypeptide-associated complex subunit alpha-like protein {ECO:0000305};
DE   AltName: Full=Alpha-NAC pseudogene 1;
DE   AltName: Full=NAC-alpha pseudogene 1;
DE   AltName: Full=NACA family member 4, pseudogene {ECO:0000312|HGNC:HGNC:24688};
GN   Name=NACA4P {ECO:0000312|HGNC:HGNC:24688};
GN   Synonyms=NACAP1 {ECO:0000312|HGNC:HGNC:24688}; ORFNames=FKSG17;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Wang Y.-G., Gong L.;
RT   "Cloning of FKSG17, a novel gene located on human chromosome 8.";
RL   Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA   Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T.,
RA   Bennett K.L., Superti-Furga G., Colinge J.;
RT   "Initial characterization of the human central proteome.";
RL   BMC Syst. Biol. 5:17-17(2011).
CC   -!- SIMILARITY: Belongs to the NAC-alpha family. {ECO:0000305}.
CC   -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
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DR   EMBL; AF315951; AAG50269.1; -; mRNA.
DR   AlphaFoldDB; Q9BZK3; -.
DR   SMR; Q9BZK3; -.
DR   IntAct; Q9BZK3; 9.
DR   MINT; Q9BZK3; -.
DR   iPTMnet; Q9BZK3; -.
DR   PhosphoSitePlus; Q9BZK3; -.
DR   BioMuta; HGNC:24688; -.
DR   DMDM; 74717760; -.
DR   EPD; Q9BZK3; -.
DR   jPOST; Q9BZK3; -.
DR   MassIVE; Q9BZK3; -.
DR   MaxQB; Q9BZK3; -.
DR   PeptideAtlas; Q9BZK3; -.
DR   PRIDE; Q9BZK3; -.
DR   ProteomicsDB; 79863; -.
DR   GeneCards; NACA4P; -.
DR   HGNC; HGNC:24688; NACA4P.
DR   neXtProt; NX_Q9BZK3; -.
DR   InParanoid; Q9BZK3; -.
DR   PathwayCommons; Q9BZK3; -.
DR   SignaLink; Q9BZK3; -.
DR   Pharos; Q9BZK3; Tdark.
DR   Proteomes; UP000005640; Unplaced.
DR   RNAct; Q9BZK3; protein.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005854; C:nascent polypeptide-associated complex; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IBA:GO_Central.
DR   GO; GO:0006612; P:protein targeting to membrane; IBA:GO_Central.
DR   Gene3D; 2.20.70.30; -; 1.
DR   InterPro; IPR016641; EGD2/NACA.
DR   InterPro; IPR038187; NAC_A/B_dom_sf.
DR   InterPro; IPR002715; Nas_poly-pep-assoc_cplx_dom.
DR   PANTHER; PTHR21713; PTHR21713; 1.
DR   Pfam; PF01849; NAC; 1.
DR   PIRSF; PIRSF015901; NAC_alpha; 1.
DR   SMART; SM01407; NAC; 1.
DR   PROSITE; PS51151; NAC_AB; 1.
PE   5: Uncertain;
KW   Acetylation; Isopeptide bond; Phosphoprotein; Reference proteome;
KW   Ubl conjugation.
FT   CHAIN           1..213
FT                   /note="Putative nascent polypeptide-associated complex
FT                   subunit alpha-like protein"
FT                   /id="PRO_0000280747"
FT   DOMAIN          69..134
FT                   /note="NAC-A/B"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00507"
FT   DOMAIN          175..211
FT                   /note="UBA"
FT   REGION          1..46
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        11..31
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         43
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q13765"
FT   MOD_RES         131
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q13765"
FT   MOD_RES         141
FT                   /note="N6-acetyllysine; alternate"
FT                   /evidence="ECO:0000250|UniProtKB:Q13765"
FT   MOD_RES         160
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:Q13765"
FT   MOD_RES         165
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q13765"
FT   MOD_RES         185
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q13765"
FT   MOD_RES         201
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q13765"
FT   MOD_RES         212
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9H009"
FT   CROSSLNK        141
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in SUMO2); alternate"
FT                   /evidence="ECO:0000250|UniProtKB:Q13765"
SQ   SEQUENCE   213 AA;  23306 MW;  733B292ADDA1CD86 CRC64;
     MPGEATETVP AIEQQLLQPQ AETGSGTESD SDESVPELEE QDSTQVTAQV QLVVAAEIDE
     EPVSKAKQRR SEKKARKARF KLGLQQVTGV TRVTIRKSKN ILFVITKPDV YKSPASDTYM
     VFGEAKIEDL SQEAQLAAAE KFKVQGEAVS NIQENTQTPT VQEGSEDEEV DETGVEIKDI
     ELVLSQANVW GAKAVRALKN SNDIVNAIME LTM