ID   NAC_HALSA               Reviewed;         130 AA.
AC   Q9HS36;
DT   25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   25-MAY-2022, entry version 93.
DE   RecName: Full=Nascent polypeptide-associated complex protein {ECO:0000255|HAMAP-Rule:MF_00814};
GN   Name=nac {ECO:0000255|HAMAP-Rule:MF_00814}; OrderedLocusNames=VNG_0424C;
OS   Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
OS   (Halobacterium halobium).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Halobacteriaceae; Halobacterium.
OX   NCBI_TaxID=64091;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700922 / JCM 11081 / NRC-1;
RX   PubMed=11016950; DOI=10.1073/pnas.190337797;
RA   Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D.,
RA   Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D.,
RA   Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K., Cruz R.,
RA   Danson M.J., Hough D.W., Maddocks D.G., Jablonski P.E., Krebs M.P.,
RA   Angevine C.M., Dale H., Isenbarger T.A., Peck R.F., Pohlschroder M.,
RA   Spudich J.L., Jung K.-H., Alam M., Freitas T., Hou S., Daniels C.J.,
RA   Dennis P.P., Omer A.D., Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L.,
RA   DasSarma S.;
RT   "Genome sequence of Halobacterium species NRC-1.";
RL   Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000).
CC   -!- FUNCTION: Contacts the emerging nascent chain on the ribosome.
CC       {ECO:0000255|HAMAP-Rule:MF_00814}.
CC   -!- SUBUNIT: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.
CC       {ECO:0000255|HAMAP-Rule:MF_00814}.
CC   -!- SIMILARITY: Belongs to the NAC-alpha family. {ECO:0000255|HAMAP-
CC       Rule:MF_00814}.
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DR   EMBL; AE004437; AAG18972.1; -; Genomic_DNA.
DR   PIR; H84200; H84200.
DR   RefSeq; WP_010902267.1; NC_002607.1.
DR   AlphaFoldDB; Q9HS36; -.
DR   SMR; Q9HS36; -.
DR   STRING; 64091.VNG_0424C; -.
DR   PaxDb; Q9HS36; -.
DR   EnsemblBacteria; AAG18972; AAG18972; VNG_0424C.
DR   GeneID; 5953679; -.
DR   KEGG; hal:VNG_0424C; -.
DR   PATRIC; fig|64091.14.peg.316; -.
DR   HOGENOM; CLU_146475_1_0_2; -.
DR   InParanoid; Q9HS36; -.
DR   OMA; PRKMKQM; -.
DR   OrthoDB; 105165at2157; -.
DR   Proteomes; UP000000554; Chromosome.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.20.70.30; -; 1.
DR   HAMAP; MF_00814; NAC_arch; 1.
DR   InterPro; IPR038187; NAC_A/B_dom_sf.
DR   InterPro; IPR005231; NAC_arc.
DR   InterPro; IPR002715; Nas_poly-pep-assoc_cplx_dom.
DR   Pfam; PF01849; NAC; 1.
DR   SMART; SM01407; NAC; 1.
DR   TIGRFAMs; TIGR00264; TIGR00264; 1.
DR   PROSITE; PS51151; NAC_AB; 1.
PE   3: Inferred from homology;
KW   Protein transport; Reference proteome; RNA-binding; Transport.
FT   CHAIN           1..130
FT                   /note="Nascent polypeptide-associated complex protein"
FT                   /id="PRO_0000135598"
FT   DOMAIN          6..74
FT                   /note="NAC-A/B"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00814"
FT   REGION          65..91
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        76..91
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   130 AA;  13870 MW;  E523A6ACD471E897 CRC64;
     MFGGGGMNPR KMQQMMEQMG IDVDELDATE VVISLDDGTE VVFSDPDVTK MDARGQETYQ
     VLGDPVERDA ADAIEAAPAD DSDDTDDDDA IPQGDVDIVV QRASVPEDEA REALEAADGD
     LAAAIDHVDE