NAC_META3
ID NAC_META3 Reviewed; 130 AA.
AC A6UVF4;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 21-AUG-2007, sequence version 1.
DT 25-MAY-2022, entry version 69.
DE RecName: Full=Nascent polypeptide-associated complex protein {ECO:0000255|HAMAP-Rule:MF_00814};
GN Name=nac {ECO:0000255|HAMAP-Rule:MF_00814}; OrderedLocusNames=Maeo_0895;
OS Methanococcus aeolicus (strain ATCC BAA-1280 / DSM 17508 / OCM 812 /
OS Nankai-3).
OC Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC Methanococcaceae; Methanococcus.
OX NCBI_TaxID=419665;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1280 / DSM 17508 / OCM 812 / Nankai-3;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A.,
RA Sieprawska-Lupa M., Whitman W.B., Richardson P.;
RT "Complete sequence of Methanococcus aeolicus Nankai-3.";
RL Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Contacts the emerging nascent chain on the ribosome.
CC {ECO:0000255|HAMAP-Rule:MF_00814}.
CC -!- SUBUNIT: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.
CC {ECO:0000255|HAMAP-Rule:MF_00814}.
CC -!- SIMILARITY: Belongs to the NAC-alpha family. {ECO:0000255|HAMAP-
CC Rule:MF_00814}.
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DR EMBL; CP000743; ABR56476.1; -; Genomic_DNA.
DR RefSeq; WP_011973608.1; NC_009635.1.
DR AlphaFoldDB; A6UVF4; -.
DR SMR; A6UVF4; -.
DR STRING; 419665.Maeo_0895; -.
DR EnsemblBacteria; ABR56476; ABR56476; Maeo_0895.
DR GeneID; 5326700; -.
DR KEGG; mae:Maeo_0895; -.
DR eggNOG; arCOG04061; Archaea.
DR HOGENOM; CLU_146475_1_0_2; -.
DR OMA; PRKMKQM; -.
DR OrthoDB; 105165at2157; -.
DR Proteomes; UP000001106; Chromosome.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-UniRule.
DR Gene3D; 2.20.70.30; -; 1.
DR HAMAP; MF_00814; NAC_arch; 1.
DR InterPro; IPR044034; NAC-like_UBA.
DR InterPro; IPR038187; NAC_A/B_dom_sf.
DR InterPro; IPR005231; NAC_arc.
DR InterPro; IPR002715; Nas_poly-pep-assoc_cplx_dom.
DR InterPro; IPR009060; UBA-like_sf.
DR Pfam; PF19026; HYPK_UBA; 1.
DR Pfam; PF01849; NAC; 1.
DR SMART; SM01407; NAC; 1.
DR SUPFAM; SSF46934; SSF46934; 1.
DR TIGRFAMs; TIGR00264; TIGR00264; 1.
DR PROSITE; PS51151; NAC_AB; 1.
PE 3: Inferred from homology;
KW Protein transport; Reference proteome; RNA-binding; Transport.
FT CHAIN 1..130
FT /note="Nascent polypeptide-associated complex protein"
FT /id="PRO_1000083766"
FT DOMAIN 8..75
FT /note="NAC-A/B"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00814"
SQ SEQUENCE 130 AA; 15051 MW; 73266A7465006A31 CRC64;
MFPGRMNPKM MRQMQKMMSD MGMDSKDIKV LKITMELEDK IMVFEKPKVQ VMDVMGNKTY
TITGRAKNIK KDDIKAEQKE QIKDEEVKLD ITKEDIEMVV NQCEVSEEEA KKVLEECNGD
IAEAILKLSQ