NAC_METMP
ID NAC_METMP Reviewed; 126 AA.
AC Q6M0I0;
DT 25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 84.
DE RecName: Full=Nascent polypeptide-associated complex protein {ECO:0000255|HAMAP-Rule:MF_00814};
GN Name=nac {ECO:0000255|HAMAP-Rule:MF_00814}; OrderedLocusNames=MMP0290;
OS Methanococcus maripaludis (strain S2 / LL).
OC Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC Methanococcaceae; Methanococcus.
OX NCBI_TaxID=267377;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S2 / LL;
RX PubMed=15466049; DOI=10.1128/jb.186.20.6956-6969.2004;
RA Hendrickson E.L., Kaul R., Zhou Y., Bovee D., Chapman P., Chung J.,
RA Conway de Macario E., Dodsworth J.A., Gillett W., Graham D.E., Hackett M.,
RA Haydock A.K., Kang A., Land M.L., Levy R., Lie T.J., Major T.A.,
RA Moore B.C., Porat I., Palmeiri A., Rouse G., Saenphimmachak C., Soell D.,
RA Van Dien S., Wang T., Whitman W.B., Xia Q., Zhang Y., Larimer F.W.,
RA Olson M.V., Leigh J.A.;
RT "Complete genome sequence of the genetically tractable hydrogenotrophic
RT methanogen Methanococcus maripaludis.";
RL J. Bacteriol. 186:6956-6969(2004).
CC -!- FUNCTION: Contacts the emerging nascent chain on the ribosome.
CC {ECO:0000255|HAMAP-Rule:MF_00814}.
CC -!- SUBUNIT: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.
CC {ECO:0000255|HAMAP-Rule:MF_00814}.
CC -!- SIMILARITY: Belongs to the NAC-alpha family. {ECO:0000255|HAMAP-
CC Rule:MF_00814}.
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DR EMBL; BX950229; CAF29846.1; -; Genomic_DNA.
DR RefSeq; WP_011170234.1; NC_005791.1.
DR AlphaFoldDB; Q6M0I0; -.
DR SMR; Q6M0I0; -.
DR STRING; 267377.MMP0290; -.
DR EnsemblBacteria; CAF29846; CAF29846; MMP0290.
DR GeneID; 2761263; -.
DR KEGG; mmp:MMP0290; -.
DR PATRIC; fig|267377.15.peg.293; -.
DR eggNOG; arCOG04061; Archaea.
DR HOGENOM; CLU_146475_1_0_2; -.
DR OMA; PRKMKQM; -.
DR OrthoDB; 105165at2157; -.
DR BioCyc; MMAR267377:MMP_RS01560-MON; -.
DR Proteomes; UP000000590; Chromosome.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-UniRule.
DR Gene3D; 2.20.70.30; -; 1.
DR HAMAP; MF_00814; NAC_arch; 1.
DR InterPro; IPR044034; NAC-like_UBA.
DR InterPro; IPR038187; NAC_A/B_dom_sf.
DR InterPro; IPR005231; NAC_arc.
DR InterPro; IPR002715; Nas_poly-pep-assoc_cplx_dom.
DR InterPro; IPR009060; UBA-like_sf.
DR Pfam; PF19026; HYPK_UBA; 1.
DR Pfam; PF01849; NAC; 1.
DR SMART; SM01407; NAC; 1.
DR SUPFAM; SSF46934; SSF46934; 1.
DR TIGRFAMs; TIGR00264; TIGR00264; 1.
DR PROSITE; PS51151; NAC_AB; 1.
PE 3: Inferred from homology;
KW Protein transport; Reference proteome; RNA-binding; Transport.
FT CHAIN 1..126
FT /note="Nascent polypeptide-associated complex protein"
FT /id="PRO_0000135602"
FT DOMAIN 10..77
FT /note="NAC-A/B"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00814"
SQ SEQUENCE 126 AA; 14130 MW; 3192B5CE96BB49E3 CRC64;
MFPGGGKFNP RMMKQMQKMM KDFGMDAEDL KAVKVTIELE DKLLVFEKPK VQVMDMLGNK
TYSITGKAKK VAKEEEKIED VEVKVEVTEE DIDMVSNQCG VSKEEAKKAL EEVNGDLAEA
ILKLGN