ID   NAC_NATPD               Reviewed;         124 AA.
AC   Q3IUB3;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Nascent polypeptide-associated complex protein {ECO:0000255|HAMAP-Rule:MF_00814};
GN   Name=nac {ECO:0000255|HAMAP-Rule:MF_00814}; OrderedLocusNames=NP_0354A;
OS   Natronomonas pharaonis (strain ATCC 35678 / DSM 2160 / CIP 103997 / JCM
OS   8858 / NBRC 14720 / NCIMB 2260 / Gabara) (Halobacterium pharaonis).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Haloarculaceae; Natronomonas.
OX   NCBI_TaxID=348780;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35678 / DSM 2160 / CIP 103997 / JCM 8858 / NBRC 14720 / NCIMB
RC   2260 / Gabara;
RX   PubMed=16169924; DOI=10.1101/gr.3952905;
RA   Falb M., Pfeiffer F., Palm P., Rodewald K., Hickmann V., Tittor J.,
RA   Oesterhelt D.;
RT   "Living with two extremes: conclusions from the genome sequence of
RT   Natronomonas pharaonis.";
RL   Genome Res. 15:1336-1343(2005).
CC   -!- FUNCTION: Contacts the emerging nascent chain on the ribosome.
CC       {ECO:0000255|HAMAP-Rule:MF_00814}.
CC   -!- SUBUNIT: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.
CC       {ECO:0000255|HAMAP-Rule:MF_00814}.
CC   -!- SIMILARITY: Belongs to the NAC-alpha family. {ECO:0000255|HAMAP-
CC       Rule:MF_00814}.
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DR   EMBL; CR936257; CAI48268.1; -; Genomic_DNA.
DR   RefSeq; WP_011321906.1; NC_007426.1.
DR   AlphaFoldDB; Q3IUB3; -.
DR   SMR; Q3IUB3; -.
DR   STRING; 348780.NP_0354A; -.
DR   EnsemblBacteria; CAI48268; CAI48268; NP_0354A.
DR   GeneID; 3700828; -.
DR   KEGG; nph:NP_0354A; -.
DR   eggNOG; arCOG04061; Archaea.
DR   HOGENOM; CLU_146475_1_0_2; -.
DR   OMA; PRKMKQM; -.
DR   OrthoDB; 105165at2157; -.
DR   Proteomes; UP000002698; Chromosome.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.20.70.30; -; 1.
DR   HAMAP; MF_00814; NAC_arch; 1.
DR   InterPro; IPR038187; NAC_A/B_dom_sf.
DR   InterPro; IPR005231; NAC_arc.
DR   InterPro; IPR002715; Nas_poly-pep-assoc_cplx_dom.
DR   Pfam; PF01849; NAC; 1.
DR   SMART; SM01407; NAC; 1.
DR   TIGRFAMs; TIGR00264; TIGR00264; 1.
DR   PROSITE; PS51151; NAC_AB; 1.
PE   3: Inferred from homology;
KW   Protein transport; Reference proteome; RNA-binding; Transport.
FT   CHAIN           1..124
FT                   /note="Nascent polypeptide-associated complex protein"
FT                   /id="PRO_1000083770"
FT   DOMAIN          7..74
FT                   /note="NAC-A/B"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00814"
FT   REGION          53..124
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   124 AA;  13448 MW;  C4D86CCE5B0B029F CRC64;
     MFGGGGGLNP RKMKQMMNQM GIDLEEIDAE EVVIRTADEE LVFDDAEVQL MDAQGQQTYQ
     VVGEPESRER GDSGSEDDSE TESGGEFSED DVEIVAQRAG VSESTARETL EETGDLAAAV
     QKLE