NAC_PICTO
ID NAC_PICTO Reviewed; 108 AA.
AC Q6L1N3;
DT 25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 78.
DE RecName: Full=Nascent polypeptide-associated complex protein {ECO:0000255|HAMAP-Rule:MF_00814};
GN Name=nac {ECO:0000255|HAMAP-Rule:MF_00814}; OrderedLocusNames=PTO0534;
OS Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC
OS 100828).
OC Archaea; Candidatus Thermoplasmatota; Thermoplasmata; Thermoplasmatales;
OC Picrophilaceae; Picrophilus.
OX NCBI_TaxID=263820;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828;
RX PubMed=15184674; DOI=10.1073/pnas.0401356101;
RA Fuetterer O., Angelov A., Liesegang H., Gottschalk G., Schleper C.,
RA Schepers B., Dock C., Antranikian G., Liebl W.;
RT "Genome sequence of Picrophilus torridus and its implications for life
RT around pH 0.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:9091-9096(2004).
CC -!- FUNCTION: Contacts the emerging nascent chain on the ribosome.
CC {ECO:0000255|HAMAP-Rule:MF_00814}.
CC -!- SUBUNIT: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.
CC {ECO:0000255|HAMAP-Rule:MF_00814}.
CC -!- SIMILARITY: Belongs to the NAC-alpha family. {ECO:0000255|HAMAP-
CC Rule:MF_00814}.
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DR EMBL; AE017261; AAT43119.1; -; Genomic_DNA.
DR RefSeq; WP_011177335.1; NC_005877.1.
DR AlphaFoldDB; Q6L1N3; -.
DR SMR; Q6L1N3; -.
DR STRING; 263820.PTO0534; -.
DR EnsemblBacteria; AAT43119; AAT43119; PTO0534.
DR GeneID; 2843976; -.
DR KEGG; pto:PTO0534; -.
DR PATRIC; fig|263820.9.peg.562; -.
DR eggNOG; arCOG04061; Archaea.
DR HOGENOM; CLU_146475_1_0_2; -.
DR OMA; PRKMKQM; -.
DR OrthoDB; 105165at2157; -.
DR Proteomes; UP000000438; Chromosome.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-UniRule.
DR Gene3D; 2.20.70.30; -; 1.
DR HAMAP; MF_00814; NAC_arch; 1.
DR InterPro; IPR044034; NAC-like_UBA.
DR InterPro; IPR038187; NAC_A/B_dom_sf.
DR InterPro; IPR005231; NAC_arc.
DR InterPro; IPR002715; Nas_poly-pep-assoc_cplx_dom.
DR InterPro; IPR009060; UBA-like_sf.
DR Pfam; PF19026; HYPK_UBA; 1.
DR Pfam; PF01849; NAC; 1.
DR SMART; SM01407; NAC; 1.
DR SUPFAM; SSF46934; SSF46934; 1.
DR PROSITE; PS51151; NAC_AB; 1.
PE 3: Inferred from homology;
KW Protein transport; Reference proteome; RNA-binding; Transport.
FT CHAIN 1..108
FT /note="Nascent polypeptide-associated complex protein"
FT /id="PRO_0000135606"
FT DOMAIN 1..68
FT /note="NAC-A/B"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00814"
SQ SEQUENCE 108 AA; 12204 MW; B6983551BC6E4DC5 CRC64;
MNPREIRRMM AQMGIKSTEM SDVKQVIFKG KDKDYIIDNA SVTMIEAQGQ KTFQVLGNLR
EVKKEVEQYS EDDIKLVMEQ AKVTREKAIE ALKAANGEPA QAILNLTS