ID   NAC_THEAC               Reviewed;         119 AA.
AC   Q9HI94; Q9V303;
DT   25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   25-MAY-2022, entry version 90.
DE   RecName: Full=Nascent polypeptide-associated complex protein {ECO:0000255|HAMAP-Rule:MF_00814};
GN   Name=nac {ECO:0000255|HAMAP-Rule:MF_00814}; OrderedLocusNames=Ta1447;
OS   Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC
OS   15155 / AMRC-C165).
OC   Archaea; Candidatus Thermoplasmatota; Thermoplasmata; Thermoplasmatales;
OC   Thermoplasmataceae; Thermoplasma.
OX   NCBI_TaxID=273075;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=HO-62;
RA   Iwasaki T., Iwasaki H.;
RL   Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165;
RX   PubMed=11029001; DOI=10.1038/35035069;
RA   Ruepp A., Graml W., Santos-Martinez M.-L., Koretke K.K., Volker C.,
RA   Mewes H.-W., Frishman D., Stocker S., Lupas A.N., Baumeister W.;
RT   "The genome sequence of the thermoacidophilic scavenger Thermoplasma
RT   acidophilum.";
RL   Nature 407:508-513(2000).
CC   -!- FUNCTION: Contacts the emerging nascent chain on the ribosome.
CC       {ECO:0000255|HAMAP-Rule:MF_00814}.
CC   -!- SUBUNIT: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.
CC       {ECO:0000255|HAMAP-Rule:MF_00814}.
CC   -!- SIMILARITY: Belongs to the NAC-alpha family. {ECO:0000255|HAMAP-
CC       Rule:MF_00814}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAA82798.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AB023294; BAA82798.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AL445067; CAC12567.1; -; Genomic_DNA.
DR   PIR; T37334; T37334.
DR   RefSeq; WP_010901850.1; NC_002578.1.
DR   AlphaFoldDB; Q9HI94; -.
DR   SMR; Q9HI94; -.
DR   STRING; 273075.Ta1447; -.
DR   EnsemblBacteria; CAC12567; CAC12567; CAC12567.
DR   GeneID; 1456903; -.
DR   KEGG; tac:Ta1447; -.
DR   eggNOG; arCOG04061; Archaea.
DR   HOGENOM; CLU_146475_1_0_2; -.
DR   OMA; PRKMKQM; -.
DR   OrthoDB; 105165at2157; -.
DR   Proteomes; UP000001024; Chromosome.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.20.70.30; -; 1.
DR   HAMAP; MF_00814; NAC_arch; 1.
DR   InterPro; IPR044034; NAC-like_UBA.
DR   InterPro; IPR038187; NAC_A/B_dom_sf.
DR   InterPro; IPR005231; NAC_arc.
DR   InterPro; IPR002715; Nas_poly-pep-assoc_cplx_dom.
DR   InterPro; IPR009060; UBA-like_sf.
DR   Pfam; PF19026; HYPK_UBA; 1.
DR   Pfam; PF01849; NAC; 1.
DR   SMART; SM01407; NAC; 1.
DR   SUPFAM; SSF46934; SSF46934; 1.
DR   TIGRFAMs; TIGR00264; TIGR00264; 1.
DR   PROSITE; PS51151; NAC_AB; 1.
PE   3: Inferred from homology;
KW   Protein transport; Reference proteome; RNA-binding; Transport.
FT   CHAIN           1..119
FT                   /note="Nascent polypeptide-associated complex protein"
FT                   /id="PRO_0000135613"
FT   DOMAIN          5..73
FT                   /note="NAC-A/B"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00814"
FT   CONFLICT        89
FT                   /note="E -> D (in Ref. 1; BAA82798)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        114
FT                   /note="M -> I (in Ref. 1; BAA82798)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   119 AA;  13410 MW;  C97F51A19378DB33 CRC64;
     MIPGRMNSRE MRRLMAQMGI KSTEMDDVTK VIFKGKTKDY VIDNAQVTMI EAQGVKTFQV
     VGTMREVPKE PEEKKEESFP EDDIKLVMEQ ASVSREKAIE ALKASGGEPA QAIMNLMQK