NAC_THEKO
ID NAC_THEKO Reviewed; 111 AA.
AC Q5JGB7;
DT 25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT 15-FEB-2005, sequence version 1.
DT 25-MAY-2022, entry version 88.
DE RecName: Full=Nascent polypeptide-associated complex protein {ECO:0000255|HAMAP-Rule:MF_00814};
GN Name=nac {ECO:0000255|HAMAP-Rule:MF_00814}; OrderedLocusNames=TK1973;
OS Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
OS (Pyrococcus kodakaraensis (strain KOD1)).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Thermococcus.
OX NCBI_TaxID=69014;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-918 / JCM 12380 / KOD1;
RX PubMed=15710748; DOI=10.1101/gr.3003105;
RA Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T.;
RT "Complete genome sequence of the hyperthermophilic archaeon Thermococcus
RT kodakaraensis KOD1 and comparison with Pyrococcus genomes.";
RL Genome Res. 15:352-363(2005).
CC -!- FUNCTION: Contacts the emerging nascent chain on the ribosome.
CC {ECO:0000255|HAMAP-Rule:MF_00814}.
CC -!- SUBUNIT: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.
CC {ECO:0000255|HAMAP-Rule:MF_00814}.
CC -!- SIMILARITY: Belongs to the NAC-alpha family. {ECO:0000255|HAMAP-
CC Rule:MF_00814}.
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DR EMBL; AP006878; BAD86162.1; -; Genomic_DNA.
DR RefSeq; WP_011250923.1; NC_006624.1.
DR AlphaFoldDB; Q5JGB7; -.
DR SMR; Q5JGB7; -.
DR STRING; 69014.TK1973; -.
DR EnsemblBacteria; BAD86162; BAD86162; TK1973.
DR GeneID; 3234738; -.
DR KEGG; tko:TK1973; -.
DR PATRIC; fig|69014.16.peg.1928; -.
DR eggNOG; arCOG04061; Archaea.
DR HOGENOM; CLU_146475_0_0_2; -.
DR InParanoid; Q5JGB7; -.
DR OMA; PRKMKQM; -.
DR OrthoDB; 105165at2157; -.
DR PhylomeDB; Q5JGB7; -.
DR Proteomes; UP000000536; Chromosome.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-UniRule.
DR Gene3D; 2.20.70.30; -; 1.
DR HAMAP; MF_00814; NAC_arch; 1.
DR InterPro; IPR044034; NAC-like_UBA.
DR InterPro; IPR038187; NAC_A/B_dom_sf.
DR InterPro; IPR005231; NAC_arc.
DR InterPro; IPR002715; Nas_poly-pep-assoc_cplx_dom.
DR InterPro; IPR009060; UBA-like_sf.
DR Pfam; PF19026; HYPK_UBA; 1.
DR Pfam; PF01849; NAC; 1.
DR SMART; SM01407; NAC; 1.
DR SUPFAM; SSF46934; SSF46934; 1.
DR TIGRFAMs; TIGR00264; TIGR00264; 1.
DR PROSITE; PS51151; NAC_AB; 1.
PE 3: Inferred from homology;
KW Protein transport; Reference proteome; RNA-binding; Transport.
FT CHAIN 1..111
FT /note="Nascent polypeptide-associated complex protein"
FT /id="PRO_0000135610"
FT DOMAIN 3..72
FT /note="NAC-A/B"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00814"
SQ SEQUENCE 111 AA; 12436 MW; 0C78A98A39A66CE8 CRC64;
MMGMNPRQMK KLMKQLGIKM EELEGVEEVV LRMKGKEIIL KEPAVTVMVV QGEKTYQIIP
GSEEVREVLE ISEDDIKLVM EQAGVDYDTA KKALEEAKGD LAEAILKLTE G