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NAC_THEKO
ID   NAC_THEKO               Reviewed;         111 AA.
AC   Q5JGB7;
DT   25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=Nascent polypeptide-associated complex protein {ECO:0000255|HAMAP-Rule:MF_00814};
GN   Name=nac {ECO:0000255|HAMAP-Rule:MF_00814}; OrderedLocusNames=TK1973;
OS   Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
OS   (Pyrococcus kodakaraensis (strain KOD1)).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Thermococcus.
OX   NCBI_TaxID=69014;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-918 / JCM 12380 / KOD1;
RX   PubMed=15710748; DOI=10.1101/gr.3003105;
RA   Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T.;
RT   "Complete genome sequence of the hyperthermophilic archaeon Thermococcus
RT   kodakaraensis KOD1 and comparison with Pyrococcus genomes.";
RL   Genome Res. 15:352-363(2005).
CC   -!- FUNCTION: Contacts the emerging nascent chain on the ribosome.
CC       {ECO:0000255|HAMAP-Rule:MF_00814}.
CC   -!- SUBUNIT: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.
CC       {ECO:0000255|HAMAP-Rule:MF_00814}.
CC   -!- SIMILARITY: Belongs to the NAC-alpha family. {ECO:0000255|HAMAP-
CC       Rule:MF_00814}.
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DR   EMBL; AP006878; BAD86162.1; -; Genomic_DNA.
DR   RefSeq; WP_011250923.1; NC_006624.1.
DR   AlphaFoldDB; Q5JGB7; -.
DR   SMR; Q5JGB7; -.
DR   STRING; 69014.TK1973; -.
DR   EnsemblBacteria; BAD86162; BAD86162; TK1973.
DR   GeneID; 3234738; -.
DR   KEGG; tko:TK1973; -.
DR   PATRIC; fig|69014.16.peg.1928; -.
DR   eggNOG; arCOG04061; Archaea.
DR   HOGENOM; CLU_146475_0_0_2; -.
DR   InParanoid; Q5JGB7; -.
DR   OMA; PRKMKQM; -.
DR   OrthoDB; 105165at2157; -.
DR   PhylomeDB; Q5JGB7; -.
DR   Proteomes; UP000000536; Chromosome.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.20.70.30; -; 1.
DR   HAMAP; MF_00814; NAC_arch; 1.
DR   InterPro; IPR044034; NAC-like_UBA.
DR   InterPro; IPR038187; NAC_A/B_dom_sf.
DR   InterPro; IPR005231; NAC_arc.
DR   InterPro; IPR002715; Nas_poly-pep-assoc_cplx_dom.
DR   InterPro; IPR009060; UBA-like_sf.
DR   Pfam; PF19026; HYPK_UBA; 1.
DR   Pfam; PF01849; NAC; 1.
DR   SMART; SM01407; NAC; 1.
DR   SUPFAM; SSF46934; SSF46934; 1.
DR   TIGRFAMs; TIGR00264; TIGR00264; 1.
DR   PROSITE; PS51151; NAC_AB; 1.
PE   3: Inferred from homology;
KW   Protein transport; Reference proteome; RNA-binding; Transport.
FT   CHAIN           1..111
FT                   /note="Nascent polypeptide-associated complex protein"
FT                   /id="PRO_0000135610"
FT   DOMAIN          3..72
FT                   /note="NAC-A/B"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00814"
SQ   SEQUENCE   111 AA;  12436 MW;  0C78A98A39A66CE8 CRC64;
     MMGMNPRQMK KLMKQLGIKM EELEGVEEVV LRMKGKEIIL KEPAVTVMVV QGEKTYQIIP
     GSEEVREVLE ISEDDIKLVM EQAGVDYDTA KKALEEAKGD LAEAILKLTE G
 
 
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