NADK2_ORYSJ
ID NADK2_ORYSJ Reviewed; 981 AA.
AC Q53NI2; Q0IU37;
DT 02-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 03-AUG-2022, entry version 99.
DE RecName: Full=Probable NAD kinase 2, chloroplastic;
DE EC=2.7.1.23;
DE Flags: Precursor;
GN OrderedLocusNames=Os11g0191400, LOC_Os11g08670;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16188032; DOI=10.1186/1741-7007-3-20;
RG The rice chromosomes 11 and 12 sequencing consortia;
RT "The sequence of rice chromosomes 11 and 12, rich in disease resistance
RT genes and recent gene duplications.";
RL BMC Biol. 3:20-20(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
CC -!- FUNCTION: Involved in chlorophyll synthesis and chloroplast protection
CC against oxidative damage. {ECO:0000250}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + NAD(+) = ADP + H(+) + NADP(+); Xref=Rhea:RHEA:18629,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:57540,
CC ChEBI:CHEBI:58349, ChEBI:CHEBI:456216; EC=2.7.1.23;
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the NAD kinase family. {ECO:0000305}.
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DR EMBL; AC134046; AAX95220.1; -; Genomic_DNA.
DR EMBL; DP000010; ABA91849.1; -; Genomic_DNA.
DR EMBL; AP008217; BAF27778.1; -; Genomic_DNA.
DR EMBL; AP014967; BAT13017.1; -; Genomic_DNA.
DR EMBL; AK065215; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; XP_015616979.1; XM_015761493.1.
DR AlphaFoldDB; Q53NI2; -.
DR SMR; Q53NI2; -.
DR STRING; 4530.OS11T0191400-01; -.
DR PaxDb; Q53NI2; -.
DR PRIDE; Q53NI2; -.
DR EnsemblPlants; Os11t0191400-01; Os11t0191400-01; Os11g0191400.
DR GeneID; 4349979; -.
DR Gramene; Os11t0191400-01; Os11t0191400-01; Os11g0191400.
DR KEGG; osa:4349979; -.
DR eggNOG; KOG2178; Eukaryota.
DR InParanoid; Q53NI2; -.
DR OMA; YCRIFRT; -.
DR OrthoDB; 1263874at2759; -.
DR Proteomes; UP000000763; Chromosome 11.
DR Proteomes; UP000059680; Chromosome 11.
DR ExpressionAtlas; Q53NI2; baseline and differential.
DR Genevisible; Q53NI2; OS.
DR GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR GO; GO:0003951; F:NAD+ kinase activity; IBA:GO_Central.
DR GO; GO:0019674; P:NAD metabolic process; IEA:InterPro.
DR GO; GO:0006741; P:NADP biosynthetic process; IBA:GO_Central.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 2.60.200.30; -; 1.
DR Gene3D; 3.40.50.10330; -; 1.
DR Gene3D; 3.90.190.10; -; 1.
DR HAMAP; MF_00361; NAD_kinase; 1.
DR InterPro; IPR017438; ATP-NAD_kinase_N.
DR InterPro; IPR017437; ATP-NAD_kinase_PpnK-typ_C.
DR InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR InterPro; IPR002504; NADK.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR Pfam; PF01513; NAD_kinase; 1.
DR SUPFAM; SSF111331; SSF111331; 1.
DR SUPFAM; SSF52799; SSF52799; 1.
PE 2: Evidence at transcript level;
KW ATP-binding; Calmodulin-binding; Chloroplast; Kinase; NAD; NADP;
KW Nucleotide-binding; Plastid; Reference proteome; Transferase;
KW Transit peptide.
FT TRANSIT 1..?
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN ?..981
FT /note="Probable NAD kinase 2, chloroplastic"
FT /id="PRO_0000233706"
FT REGION 319..364
FT /note="Calmodulin-binding"
FT /evidence="ECO:0000250"
FT REGION 369..413
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 551..601
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 369..410
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 610
FT /note="K -> R (in Ref. 5; AK065215)"
FT /evidence="ECO:0000305"
FT CONFLICT 809
FT /note="L -> V (in Ref. 5; AK065215)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 981 AA; 108613 MW; 18DECA59F458B6B6 CRC64;
MLAVCARHGP AKLPPPPPPL AGERAAAWVV GRWWWRPAAA GRRGVVAARA SFFSSRIGLD
SQNYHTRDLS QLLWVGPVPG DIAEIEAYCR IFRAAEQLHT AVMSALCDPE TGECPVRYDV
QTEDLPVLED KVAAVLGCML ALLNRGRKEV LSGRSGVASA FQGSEDSTMD KIPPLALFRG
DLKRCCESMQ VALASYLVPS EARGLDIWRK LQRLKNACYD AGFPRADGHP CPTLFANWFP
VYFSTVPDDS LSDELEVAFW RGGQVSEEGL EWLLLKGFKT IVDLREEDVK DDLYLSAIHE
AVSLGKIEVV NLPVEIGTAP SAEQVQRFAE IVSDSAKKPI YLHSQEGISR TSAMVSRWKQ
YVTRAERLAT QNRSLNGNGK HVRNDQTEQL TNSPGFSSEG SENGTPLESD RTMEGETCDI
DIETARHNLE ITNSLPSEQS TEQGELHGTR TELQSNFRLE SNPLKAQFPS CDVFSKKGMT
DFFRSKKVYP KSVLNPRRRS NSLLVSRRKQ SLSAEQNGAI DYEAAEFKVL KSSNGASFDN
DYILSVASGI TNGKPSNNGA STSVEDREME TSVVTVDPRT SDTSNSNGNA PLGSQKSAER
NGSLYVEREK SDHVDGNMCA SATGVVRLQS RRKAEMFLVR TDGFSCTREK VTESSLAFTH
PSTQQQMLMW KSPPKTVLLL KKLGDELMEE AKEVASFLHH QEKMNVLVEP DVHDIFARIP
GYGFVQTFYT QDTSDLHERV DFVACLGGDG VILHASNLFR TSVPPVVSFN LGSLGFLTSH
NFEGFRQDLR AVIHGNNTLG VYITLRMRLR CEIFRNGKAM PGKVFDVLNE VVVDRGSNPY
LSKIECYEHN HLITKVQGDG VIVATPTGST AYSTAAGGSM VHPNVPCMLF TPICPHSLSF
RPVILPDSAR LELKIPDDAR SNAWVSFDGK RRQQLSRGDS VQISMSQHPL PTVNKSDQTG
DWFRSLIRCL NWNERLDQKA L
