ID   NAM1_HORVV              Reviewed;         406 AA.
AC   A0SPJ8; B0FZ69;
DT   28-NOV-2012, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 1.
DT   25-MAY-2022, entry version 52.
DE   RecName: Full=NAC transcription factor NAM-1;
DE            Short=HvNAM-1;
GN   Name=NAM-1;
OS   Hordeum vulgare subsp. vulgare (Domesticated barley).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Hordeinae; Hordeum.
OX   NCBI_TaxID=112509;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND FUNCTION.
RX   PubMed=17124321; DOI=10.1126/science.1133649;
RA   Uauy C., Distelfeld A., Fahima T., Blechl A., Dubcovsky J.;
RT   "A NAC Gene regulating senescence improves grain protein, zinc, and iron
RT   content in wheat.";
RL   Science 314:1298-1301(2006).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   DOI=10.1007/s11032-007-9153-3;
RA   Distelfeld A., Korol A., Dubcovsky J., Uauy C., Blake T., Fahima T.;
RT   "Colinearity between the barley grain protein content (GPC) QTL on
RT   chromosome arm 6HS and the wheat Gpc-B1 region.";
RL   Mol. Breed. 22:25-38(2008).
RN   [3]
RP   FUNCTION.
RX   PubMed=20005003; DOI=10.1016/j.jplph.2009.10.014;
RA   Jamar C., Loffet F., Frettinger P., Ramsay L., Fauconnier M.L.,
RA   du Jardin P.;
RT   "NAM-1gene polymorphism and grain protein content in Hordeum.";
RL   J. Plant Physiol. 167:497-501(2010).
CC   -!- FUNCTION: Transcription factor of the NAC family associated with the
CC       grain protein content (GPC). Accelerates senescence and increases
CC       nutrient remobilization from leaves to developing grains. Sequences of
CC       11 European varieties of H.vulgare tested belongs to the same haplotype
CC       while the sequence found in H.spontaneum, an ancestor of the cultivated
CC       H.vulgare which has a higher GPC, belongs to an other haplotype.
CC       {ECO:0000269|PubMed:17124321, ECO:0000269|PubMed:20005003}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- DOMAIN: The NAC domain includes a DNA-binding domain and a dimerization
CC       domain.
CC   -!- MISCELLANEOUS: High grain protein content (GPC) is a desirable trait in
CC       breadmaking and pasta wheat varieties because of its positive effects
CC       on quality and nutritional value while Low GPC is a desirable trait for
CC       barley malt and beer production.
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DR   EMBL; DQ869678; ABI94357.1; -; Genomic_DNA.
DR   EMBL; EU368851; ABY67949.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0SPJ8; -.
DR   SMR; A0SPJ8; -.
DR   STRING; 112509.A0SPJ8; -.
DR   InParanoid; A0SPJ8; -.
DR   Proteomes; UP000011116; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0048731; P:system development; IBA:GO_Central.
DR   Gene3D; 2.170.150.80; -; 1.
DR   InterPro; IPR003441; NAC-dom.
DR   InterPro; IPR036093; NAC_dom_sf.
DR   Pfam; PF02365; NAM; 1.
DR   SUPFAM; SSF101941; SSF101941; 1.
DR   PROSITE; PS51005; NAC; 1.
PE   4: Predicted;
KW   DNA-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..406
FT                   /note="NAC transcription factor NAM-1"
FT                   /id="PRO_0000420375"
FT   DOMAIN          35..204
FT                   /note="NAC"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00353"
FT   DNA_BIND        137..210
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00353"
FT   REGION          1..40
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..17
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   406 AA;  43491 MW;  777062F64EC94B4C CRC64;
     MGSPDSSSGS AQKPPRHQHQ HQPPPPRRQG SAPELPPGFR FHPTDEELVV HYLKKKAAKA
     PLPVTIIAEV DLYKFDPWEL PEKATFGEHE WYFFSPRDRK YANGARPNRA ATSGYWKATG
     TDKPILASAT GCGREKVGVK KALVFYRGKP PRGLKTNWIM HEYRLTGASA GSTTTSRPPP
     VTGGSRAPAS LRLDDWVLCR IYKKTSKAAA AVGDEQRSME CEDSVEDAVT AYPPYATAGM
     AGAGAHGSNY VQLLHHHDSH EDNFQLDGLL TEHDVGLSAG AASLGHLAAA ARATKQFLAP
     SSSTPFNWLE ASTGGSILPQ ARNFPGFNRS RNVGSMSLSS TADDMAGAVD VSDGGNAVNA
     MYLPVQDGTY HQHVILGAPL APEAIAGAAT SGFQHHVQIS GVNWNP