ID   NAM2_HORVV              Reviewed;         402 AA.
AC   A0SPJ9;
DT   28-NOV-2012, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 1.
DT   25-MAY-2022, entry version 43.
DE   RecName: Full=NAC transcription factor NAM-2;
DE            Short=HvNAM-2;
GN   Name=NAM-2;
OS   Hordeum vulgare subsp. vulgare (Domesticated barley).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Hordeinae; Hordeum.
OX   NCBI_TaxID=112509;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND FUNCTION.
RX   PubMed=17124321; DOI=10.1126/science.1133649;
RA   Uauy C., Distelfeld A., Fahima T., Blechl A., Dubcovsky J.;
RT   "A NAC Gene regulating senescence improves grain protein, zinc, and iron
RT   content in wheat.";
RL   Science 314:1298-1301(2006).
CC   -!- FUNCTION: Transcription factor of the NAC family associated with the
CC       grain protein content (GPC). Accelerates senescence and increases
CC       nutrient remobilization from leaves to developing grains. Sequences of
CC       11 European varieties of H.vulgare tested belongs to the same haplotype
CC       while the sequence found in H.spontaneum, an ancestor of the cultivated
CC       H.vulgare which has a higher GPC, belongs to an other haplotype.
CC       {ECO:0000269|PubMed:17124321}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- DOMAIN: The NAC domain includes a DNA-binding domain and a dimerization
CC       domain.
CC   -!- MISCELLANEOUS: High grain protein content (GPC) is a desirable trait in
CC       breadmaking and pasta wheat varieties because of its positive effects
CC       on quality and nutritional value while Low GPC is a desirable trait for
CC       barley malt and beer production.
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DR   EMBL; DQ869679; ABI94358.1; -; Genomic_DNA.
DR   STRING; 112509.A0SPJ9; -.
DR   PRIDE; A0SPJ9; -.
DR   eggNOG; ENOG502QRBC; Eukaryota.
DR   InParanoid; A0SPJ9; -.
DR   Proteomes; UP000011116; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0048731; P:system development; IBA:GO_Central.
DR   Gene3D; 2.170.150.80; -; 1.
DR   InterPro; IPR003441; NAC-dom.
DR   InterPro; IPR036093; NAC_dom_sf.
DR   Pfam; PF02365; NAM; 1.
DR   SUPFAM; SSF101941; SSF101941; 1.
DR   PROSITE; PS51005; NAC; 1.
PE   4: Predicted;
KW   DNA-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..402
FT                   /note="NAC transcription factor NAM-2"
FT                   /id="PRO_0000420376"
FT   DOMAIN          28..193
FT                   /note="NAC"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00353"
FT   DNA_BIND        128..199
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00353"
FT   REGION          1..35
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        12..26
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   402 AA;  43016 MW;  BBCDD90F1F4BE598 CRC64;
     MGSSDSSSGS APPRHQPPPP QQGSAPELPP GFRFHPTDEE LVVHYLKKKA AKVPLPVTII
     AEVDLYKFDP WELPEKATFG EQEWYFFSPR DRKYPNGARP NRAATSGYWK ATGTDKPILA
     SGCGREKVGV KXALVFYRGK PPKGLKTNWI MHEYRLTDAS SSAATSRPPP VTGGSRAASL
     RLDDWVLCRI YKKINKAAAA DQQRSMECED SVEDAVTAYP PYATACMTGE GAHGSNYASL
     LHHQDSHEDN FLDGLLTAED AGLSAGATSL SHLAAAARGS PAPTKQFLAP SSSTQFNWLD
     ASTVGILPHA RNFPGFNRSR NVGNMSLSST ADMAGAGTCA VDNGGGNAMN VMPPFMNHLP
     VQDGTYHQQH VILGAPLAPE ATGAAASAFQ HPVQISGVNW NP