ID   NAMA1_TRITD             Reviewed;         405 AA.
AC   A0SPJ3;
DT   28-NOV-2012, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 1.
DT   25-MAY-2022, entry version 45.
DE   RecName: Full=NAC transcription factor NAM-A1;
DE            Short=TtNAM-A1;
GN   Name=NAM-A1;
OS   Triticum turgidum subsp. durum (Durum wheat) (Triticum durum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX   NCBI_TaxID=4567;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, TISSUE SPECIFICITY, AND
RP   DEVELOPMENTAL STAGE.
RX   PubMed=17124321; DOI=10.1126/science.1133649;
RA   Uauy C., Distelfeld A., Fahima T., Blechl A., Dubcovsky J.;
RT   "A NAC Gene regulating senescence improves grain protein, zinc, and iron
RT   content in wheat.";
RL   Science 314:1298-1301(2006).
RN   [2]
RP   FUNCTION, AND DISRUPTION PHENOTYPE.
RX   PubMed=22278768; DOI=10.1007/s11103-012-9881-6;
RA   Distelfeld A., Pearce S.P., Avni R., Scherer B., Uauy C., Piston F.,
RA   Slade A., Zhao R., Dubcovsky J.;
RT   "Divergent functions of orthologous NAC transcription factors in wheat and
RT   rice.";
RL   Plant Mol. Biol. 78:515-524(2012).
CC   -!- FUNCTION: Transcription factor of the NAC family associated with the
CC       grain protein content (GPC). Accelerates senescence and increases
CC       nutrient remobilization from leaves to developing grains. The
CC       tetraploid cultivated wheat (T.durum) contains one additional gene
CC       coding for a functional protein (NAM-B2) and one extra pseudogene (NAM-
CC       B1) (PubMed:17124321). {ECO:0000269|PubMed:17124321,
CC       ECO:0000269|PubMed:22278768}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Expressed in flag leaves, green spikes and
CC       peduncles. {ECO:0000269|PubMed:17124321}.
CC   -!- DEVELOPMENTAL STAGE: Increased expression during grain maturation.
CC       {ECO:0000269|PubMed:17124321}.
CC   -!- DOMAIN: The NAC domain includes a DNA-binding domain and a dimerization
CC       domain.
CC   -!- DISRUPTION PHENOTYPE: No visible phenotype, but higher chlorophyll
CC       content and delayed senescence. {ECO:0000269|PubMed:22278768}.
CC   -!- MISCELLANEOUS: High grain protein content (GPC) is a desirable trait in
CC       breadmaking and pasta wheat varieties because of its positive effects
CC       on quality and nutritional value while Low GPC is a desirable trait for
CC       barley malt and beer production.
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DR   EMBL; DQ869672; ABI94352.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0SPJ3; -.
DR   SMR; A0SPJ3; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 2.170.150.80; -; 1.
DR   InterPro; IPR003441; NAC-dom.
DR   InterPro; IPR036093; NAC_dom_sf.
DR   Pfam; PF02365; NAM; 1.
DR   SUPFAM; SSF101941; SSF101941; 1.
DR   PROSITE; PS51005; NAC; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Nucleus; Transcription; Transcription regulation.
FT   CHAIN           1..405
FT                   /note="NAC transcription factor NAM-A1"
FT                   /id="PRO_0000420372"
FT   DOMAIN          33..204
FT                   /note="NAC"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00353"
FT   DNA_BIND        137..210
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00353"
FT   REGION          1..38
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   405 AA;  43196 MW;  1C604C5BB978B89C CRC64;
     MGSSDSSSGS AQKAARHQHE PPPPRQRGSA PELPPGFRFH PTDEELVVHY LKKKAAKVPL
     PVTIIAEVDL YKFDPWELPE KATFGEQEWY FFSPRDRKYP NGARPNRAAT SGYWKATGTD
     KPILASGTGC GLVREKLGVK KALVFYRGKP PKGLKTNWIM HEYRLTDVSG STTTSRPPPP
     VTGGSRAAAS LRLDDWVLCR IYKKINKAAA GDQQRSTECE DSVEDAVTAY PLYATAGMAG
     AGAHGSNYAS PSLLHHQDSH FLEGLFTADD AGLSAGATSL SHLAAAARAS PAPTKQFLAP
     SSSTPFNWLD ASPAGILPQA RNFPGFNRSR NVGNMSLSST ADMAGAAGNA VNAMSAFMNP
     LPVQDGTYHQ HHVILGAPLA PEATTGGATS GFQHPVQVSG VNWNP