ID   NANR_SALBC              Reviewed;         263 AA.
AC   F8VI19;
DT   25-JAN-2012, integrated into UniProtKB/Swiss-Prot.
DT   21-SEP-2011, sequence version 1.
DT   25-MAY-2022, entry version 58.
DE   RecName: Full=HTH-type transcriptional repressor NanR {ECO:0000255|HAMAP-Rule:MF_01236};
GN   Name=nanR {ECO:0000255|HAMAP-Rule:MF_01236}; OrderedLocusNames=SBG_2969;
OS   Salmonella bongori (strain ATCC 43975 / DSM 13772 / NCTC 12419).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=218493;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43975 / DSM 13772 / NCTC 12419;
RX   PubMed=21876672; DOI=10.1371/journal.ppat.1002191;
RA   Fookes M., Schroeder G.N., Langridge G.C., Blondel C.J., Mammina C.,
RA   Connor T.R., Seth-Smith H., Vernikos G.S., Robinson K.S., Sanders M.,
RA   Petty N.K., Kingsley R.A., Baumler A.J., Nuccio S.P., Contreras I.,
RA   Santiviago C.A., Maskell D., Barrow P., Humphrey T., Nastasi A.,
RA   Roberts M., Frankel G., Parkhill J., Dougan G., Thomson N.R.;
RT   "Salmonella bongori provides insights into the evolution of the
RT   Salmonellae.";
RL   PLoS Pathog. 7:E1002191-E1002191(2011).
CC   -!- FUNCTION: Transcriptional repressor that controls expression of the
CC       genes required for the catabolism of sialic acids. {ECO:0000255|HAMAP-
CC       Rule:MF_01236}.
CC   -!- SIMILARITY: Belongs to the NanR family. {ECO:0000255|HAMAP-
CC       Rule:MF_01236}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FR877557; CCC32023.1; -; Genomic_DNA.
DR   RefSeq; WP_000382921.1; NC_015761.1.
DR   AlphaFoldDB; F8VI19; -.
DR   SMR; F8VI19; -.
DR   EnsemblBacteria; CCC32023; CCC32023; SBG_2969.
DR   GeneID; 66757683; -.
DR   KEGG; sbg:SBG_2969; -.
DR   eggNOG; COG2186; Bacteria.
DR   OMA; HDAFVDW; -.
DR   OrthoDB; 1875458at2; -.
DR   Proteomes; UP000000289; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   CDD; cd07377; WHTH_GntR; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 1.20.120.530; -; 1.
DR   HAMAP; MF_01236; HTH_NanR; 1.
DR   InterPro; IPR011711; GntR_C.
DR   InterPro; IPR008920; TF_FadR/GntR_C.
DR   InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR   InterPro; IPR023730; Tscrpt_reg_NanR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF07729; FCD; 1.
DR   Pfam; PF00392; GntR; 1.
DR   PRINTS; PR00035; HTHGNTR.
DR   SMART; SM00895; FCD; 1.
DR   SMART; SM00345; HTH_GNTR; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF48008; SSF48008; 1.
DR   PROSITE; PS50949; HTH_GNTR; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Repressor; Transcription; Transcription regulation.
FT   CHAIN           1..263
FT                   /note="HTH-type transcriptional repressor NanR"
FT                   /id="PRO_0000415301"
FT   DOMAIN          30..98
FT                   /note="HTH gntR-type"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01236"
FT   DNA_BIND        58..77
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01236"
SQ   SEQUENCE   263 AA;  29773 MW;  4C5E8A03AF0AF137 CRC64;
     MDVMNAFDSQ AEDSPLSIGH SLRRRPLARK KLSEMVEEEL EQMIRRHEFG EGEQLPSERE
     LMAFFNVGRP SVREALAALK RKGLVQINNG ERARVSRPSA DTIISELSGM AKDFLSHPGG
     IAHFEQLRLF FESSLVRYAA EHATDEQIAL LTKALEINSQ SLDDNALFIR SDVEFHRVLA
     EIPGNPIFMA IHVALLDWLI AARPGVADRE LHEHNNLSYQ QHIAIVDAIR QRDPDKADRA
     LQTHLNSVSA TWHAFGKKNQ KMR