ID   NAP1_DICDI              Reviewed;         321 AA.
AC   Q55ED1;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Probable nucleosome assembly protein;
GN   Name=nap1; ORFNames=DDB_G0269290;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: May modulate chromatin structure by regulation of histone
CC       octamer formation. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- DOMAIN: The acidic domain may be involved in the interaction with
CC       histones.
CC   -!- SIMILARITY: Belongs to the nucleosome assembly protein (NAP) family.
CC       {ECO:0000305}.
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DR   EMBL; AAFI02000005; EAL71995.1; -; Genomic_DNA.
DR   RefSeq; XP_645850.1; XM_640758.1.
DR   AlphaFoldDB; Q55ED1; -.
DR   SMR; Q55ED1; -.
DR   STRING; 44689.DDB0267102; -.
DR   PaxDb; Q55ED1; -.
DR   EnsemblProtists; EAL71995; EAL71995; DDB_G0269290.
DR   GeneID; 8616794; -.
DR   KEGG; ddi:DDB_G0269290; -.
DR   dictyBase; DDB_G0269290; nap1.
DR   eggNOG; KOG1507; Eukaryota.
DR   HOGENOM; CLU_038841_1_0_1; -.
DR   InParanoid; Q55ED1; -.
DR   OMA; NSAYNDE; -.
DR   PhylomeDB; Q55ED1; -.
DR   PRO; PR:Q55ED1; -.
DR   Proteomes; UP000002195; Chromosome 1.
DR   GO; GO:0000785; C:chromatin; IBA:GO_Central.
DR   GO; GO:0005737; C:cytoplasm; ISS:dictyBase.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003682; F:chromatin binding; IBA:GO_Central.
DR   GO; GO:0042393; F:histone binding; ISS:dictyBase.
DR   GO; GO:0006334; P:nucleosome assembly; ISS:dictyBase.
DR   InterPro; IPR037231; NAP-like_sf.
DR   InterPro; IPR002164; NAP_family.
DR   PANTHER; PTHR11875; PTHR11875; 1.
DR   Pfam; PF00956; NAP; 1.
DR   SUPFAM; SSF143113; SSF143113; 1.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome.
FT   CHAIN           1..321
FT                   /note="Probable nucleosome assembly protein"
FT                   /id="PRO_0000330900"
FT   REGION          272..321
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        274..298
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        306..321
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   321 AA;  36644 MW;  83B3FC7A00350248 CRC64;
     MSENNEIEME LPFDSSAITS TEVLDRVNAL LTLQDTQNEL TEQMEKEILE IEKKYLKKFQ
     PLAEKRFEIV SGKVEPTKED QQCKAPIQVE NLKSVPTDKG IPKFWLHVLQ NTEVKDIIEE
     CDIEALEYLV DIKIVQVGDA QDYSLDFHFS ENPFFTNTVI SKTVKLEEDN ELNEIVSTPI
     NWKDGKNFTV QSKKKTVKSK PTKGKAATTT STTVQEVVPC FFSTFVSPNQ DPTSDEEADE
     IMYIQYQIIA KLKDIVIPEA VNFFLGRASD AEENDYDFGE DFEDEEGEDD DEEDDEEEQT
     IKKPSGKGKA QPQQPQDCKQ Q