ID   NAP1_SOLLC              Reviewed;         282 AA.
AC   K4BWV2;
DT   07-NOV-2018, integrated into UniProtKB/Swiss-Prot.
DT   28-NOV-2012, sequence version 1.
DT   03-AUG-2022, entry version 51.
DE   RecName: Full=NAC domain-containing protein 1 {ECO:0000303|PubMed:29760199};
DE            Short=SlNAP1 {ECO:0000303|PubMed:29760199};
GN   Name=NAP1 {ECO:0000303|PubMed:29760199};
GN   OrderedLocusNames=Solyc05g007770.2.1 {ECO:0000305};
OS   Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC   Solanum subgen. Lycopersicon.
OX   NCBI_TaxID=4081;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Heinz 1706;
RX   PubMed=22660326; DOI=10.1038/nature11119;
RG   Tomato Genome Consortium;
RT   "The tomato genome sequence provides insights into fleshy fruit
RT   evolution.";
RL   Nature 485:635-641(2012).
RN   [2]
RP   FUNCTION, DISRUPTION PHENOTYPE, INDUCTION BY LEAF SENESCENCE, TISSUE
RP   SPECIFICITY, GENE FAMILY, AND NOMENCLATURE.
RC   STRAIN=cv. Moneymaker;
RX   PubMed=29760199; DOI=10.1104/pp.18.00292;
RA   Ma X., Zhang Y., Tureckova V., Xue G.-P., Fernie A.R., Mueller-Roeber B.,
RA   Balazadeh S.;
RT   "The NAC transcription factor SlNAP2 regulates leaf senescence and fruit
RT   yield in tomato.";
RL   Plant Physiol. 177:1286-1302(2018).
CC   -!- FUNCTION: Transcription factor that binds DNA motifs 5'-
CC       CGT[AG](5N)NACG[ACT][AC][AT][ACG][ACT]-3' and 5'-
CC       CACG[ACT][AC][AT][AGT][CT]-3' in target genes promoters. Promotes leaf
CC       senescence and reduces fruit yield and sugar content, probably by
CC       establishing abscisic acid (ABA) homeostasis.
CC       {ECO:0000269|PubMed:29760199}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00353}.
CC   -!- TISSUE SPECIFICITY: Expressed in roots, stem, flowers, and leaves.
CC       {ECO:0000269|PubMed:29760199}.
CC   -!- INDUCTION: Accumulates during age-dependent and dark-induced leaf
CC       senescence. {ECO:0000269|PubMed:29760199}.
CC   -!- DOMAIN: The NAC domain includes a DNA binding domain and a dimerization
CC       domain. {ECO:0000255|PROSITE-ProRule:PRU00353}.
CC   -!- DISRUPTION PHENOTYPE: In plants lacking both NAP1 and NAP2, delayed
CC       leaf senescence but enhanced fruit yield and sugar content, likely due
CC       to prolonged leaf photosynthesis in aging plants.
CC       {ECO:0000269|PubMed:29760199}.
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DR   EMBL; CM001068; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_001316452.1; NM_001329523.1.
DR   AlphaFoldDB; K4BWV2; -.
DR   SMR; K4BWV2; -.
DR   STRING; 4081.Solyc05g007770.2.1; -.
DR   PaxDb; K4BWV2; -.
DR   PRIDE; K4BWV2; -.
DR   EnsemblPlants; Solyc05g007770.3.1; Solyc05g007770.3.1; Solyc05g007770.3.
DR   GeneID; 101244582; -.
DR   Gramene; Solyc05g007770.3.1; Solyc05g007770.3.1; Solyc05g007770.3.
DR   KEGG; sly:101244582; -.
DR   eggNOG; ENOG502QSIY; Eukaryota.
DR   HOGENOM; CLU_035664_8_2_1; -.
DR   InParanoid; K4BWV2; -.
DR   OMA; YFPNTID; -.
DR   OrthoDB; 1011164at2759; -.
DR   PhylomeDB; K4BWV2; -.
DR   Proteomes; UP000004994; Chromosome 5.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0010150; P:leaf senescence; IMP:UniProtKB.
DR   GO; GO:0031155; P:regulation of reproductive fruiting body development; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   Gene3D; 2.170.150.80; -; 1.
DR   InterPro; IPR003441; NAC-dom.
DR   InterPro; IPR036093; NAC_dom_sf.
DR   Pfam; PF02365; NAM; 1.
DR   SUPFAM; SSF101941; SSF101941; 1.
DR   PROSITE; PS51005; NAC; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; DNA-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..282
FT                   /note="NAC domain-containing protein 1"
FT                   /id="PRO_0000445683"
FT   DOMAIN          9..161
FT                   /note="NAC"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00353"
FT   DNA_BIND        106..167
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00353"
FT   COILED          161..188
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   282 AA;  32499 MW;  6BEAADA0B765194E CRC64;
     MVGKISSDLP PGFRFHPTDE ELIMYYLRYQ ATSRPCPVSI IPEIDVYKFD PWVLPEKAEF
     GDNEWYFFTP RDRKYPNGVR PNRAAVSGYW KATGTDKAIY SANKYVGIKK ALVFYKGKPP
     KGVKTDWIMH EYRLSDSKSQ TSKQSGSMRL DDWVLCRIYK KKNLGRTIEM MKVEEEELEA
     QNVSTTNNEI EVVGGPQTMK LPRICSLSHL LELDYFGSIP QLLSDNLLYD DQGYTMNNVN
     NTSNVDQVSS QQQNTNNITS NNCNIFFNYQ QPLFVNPTFQ SQ