NAP5_ARATH
ID NAP5_ARATH Reviewed; 324 AA.
AC Q9FVV9;
DT 03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 123.
DE RecName: Full=Probable non-intrinsic ABC protein 5;
DE AltName: Full=MRP-related protein 2;
GN Name=NAP5; OrderedLocusNames=At1g71330; ORFNames=F3I17.2;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11346655; DOI=10.1074/jbc.m103104200;
RA Sanchez-Fernandez R., Davies T.G., Coleman J.O., Rea P.A.;
RT "The Arabidopsis thaliana ABC protein superfamily, a complete inventory.";
RL J. Biol. Chem. 276:30231-30244(2001).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18299247; DOI=10.1016/j.tplants.2008.02.001;
RA Verrier P.J., Bird D., Burla B., Dassa E., Forestier C., Geisler M.,
RA Klein M., Kolukisaoglu H.U., Lee Y., Martinoia E., Murphy A., Rea P.A.,
RA Samuels L., Schulz B., Spalding E.J., Yazaki K., Theodoulou F.L.;
RT "Plant ABC proteins - a unified nomenclature and updated inventory.";
RL Trends Plant Sci. 13:151-159(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255|PROSITE-ProRule:PRU00441};
CC Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
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DR EMBL; AC016162; AAG51884.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE35190.1; -; Genomic_DNA.
DR PIR; B96738; B96738.
DR RefSeq; NP_177289.1; NM_105802.1.
DR AlphaFoldDB; Q9FVV9; -.
DR SMR; Q9FVV9; -.
DR BioGRID; 28694; 38.
DR IntAct; Q9FVV9; 38.
DR STRING; 3702.AT1G71330.1; -.
DR PaxDb; Q9FVV9; -.
DR PRIDE; Q9FVV9; -.
DR EnsemblPlants; AT1G71330.1; AT1G71330.1; AT1G71330.
DR GeneID; 843474; -.
DR Gramene; AT1G71330.1; AT1G71330.1; AT1G71330.
DR KEGG; ath:AT1G71330; -.
DR Araport; AT1G71330; -.
DR TAIR; locus:2032303; AT1G71330.
DR eggNOG; KOG0054; Eukaryota.
DR HOGENOM; CLU_000604_27_9_1; -.
DR InParanoid; Q9FVV9; -.
DR OMA; YWARTEE; -.
DR OrthoDB; 138195at2759; -.
DR PhylomeDB; Q9FVV9; -.
DR BioCyc; ARA:AT1G71330-MON; -.
DR PRO; PR:Q9FVV9; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9FVV9; baseline and differential.
DR Genevisible; Q9FVV9; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0042626; F:ATPase-coupled transmembrane transporter activity; ISS:TAIR.
DR GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR Gene3D; 1.20.1560.10; -; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF00005; ABC_tran; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR SUPFAM; SSF90123; SSF90123; 1.
DR PROSITE; PS50929; ABC_TM1F; 1.
PE 2: Evidence at transcript level;
KW ATP-binding; Membrane; Nucleotide-binding; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..324
FT /note="Probable non-intrinsic ABC protein 5"
FT /id="PRO_0000250657"
FT TRANSMEM 212..232
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 259..279
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT DOMAIN 2..111
FT /note="ABC transporter"
FT DOMAIN 222..324
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ SEQUENCE 324 AA; 35811 MW; 1FA9AAE27A276D21 CRC64;
MDRERYDKVI EACSLSKDLE ILSFGDQTVI GERGINLSGG QKQRIHIARA LYQDADIYLF
DDPFSAVDAH TGSHLFKEAL RGLLCSKSVI YVTHQVEFLP SADLTLVMKD GRISQAGKYN
DILISGTDFR ELIGAHQESL AVVGSADASS VSENSALDEE NGVVRDDIGF DGKQESQDLK
NDKLDSGEPQ RQFVQEEERA KGSVALDVYW KYITLAYGGA LVPFILLGQI LFQLLQIGSN
YWMAWATPIS EDVQAPVKLS TLMVVYVALA FGSSLCILVR ATLLVTAGYK TATELFHKMH
HCIFRSPMSF KIAKTCSKTC IYSS
