ID   NAR1_ASPTN              Reviewed;         599 AA.
AC   Q0CR17;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 64.
DE   RecName: Full=Cytosolic Fe-S cluster assembly factor nar1;
DE   AltName: Full=Nuclear architecture-related protein 1;
GN   Name=nar1; ORFNames=ATEG_03867;
OS   Aspergillus terreus (strain NIH 2624 / FGSC A1156).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=341663;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NIH 2624 / FGSC A1156;
RA   Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Henn M.,
RA   Ma L.-J., Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M.,
RA   Kleber M., Mauceli E.W., Brockman W., Rounsley S., Young S.K., LaButti K.,
RA   Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA   Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA   Alvarado L., Kodira C.D., Zeng Q., Oleary S., Yandava C., Denning D.W.,
RA   Nierman W.C., Milne T., Madden K.;
RT   "Annotation of the Aspergillus terreus NIH2624 genome.";
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the cytosolic Fe/S protein assembly machinery.
CC       Required for maturation of extramitochondrial Fe/S proteins. May play a
CC       role in the transfer of pre-assembled Fe/S clusters to target
CC       apoproteins (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NARF family. {ECO:0000305}.
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DR   EMBL; CH476598; EAU35669.1; -; Genomic_DNA.
DR   RefSeq; XP_001213045.1; XM_001213045.1.
DR   AlphaFoldDB; Q0CR17; -.
DR   SMR; Q0CR17; -.
DR   STRING; 341663.Q0CR17; -.
DR   EnsemblFungi; EAU35669; EAU35669; ATEG_03867.
DR   GeneID; 4318387; -.
DR   VEuPathDB; FungiDB:ATEG_03867; -.
DR   eggNOG; KOG2439; Eukaryota.
DR   HOGENOM; CLU_018240_0_1_1; -.
DR   OMA; PHEQRAW; -.
DR   OrthoDB; 705416at2759; -.
DR   Proteomes; UP000007963; Unassembled WGS sequence.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
DR   InterPro; IPR009016; Fe_hydrogenase.
DR   InterPro; IPR004108; Fe_hydrogenase_lsu_C.
DR   Pfam; PF02906; Fe_hyd_lg_C; 1.
DR   SUPFAM; SSF53920; SSF53920; 1.
PE   3: Inferred from homology;
KW   4Fe-4S; Iron; Iron-sulfur; Metal-binding; Reference proteome.
FT   CHAIN           1..599
FT                   /note="Cytosolic Fe-S cluster assembly factor nar1"
FT                   /id="PRO_0000383719"
FT   REGION          25..44
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        28..44
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         20
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255"
FT   BINDING         62
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255"
FT   BINDING         65
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255"
FT   BINDING         68
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255"
FT   BINDING         210
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255"
FT   BINDING         265
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255"
FT   BINDING         468
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255"
FT   BINDING         472
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   599 AA;  64611 MW;  3CC90BBD513FA7A2 CRC64;
     MSAILSADDL NDFISPGVAC IKPIESLPSK QPQKSDNPYE VTTEDKVQAE NPTPAQISLT
     DCLACSGCVT SAEAVLISLQ SHTEVLNTLD AHPELRLIQN EQGTSLDPRS AQDDEGRIFV
     ASVSPQVRAS LAATYGVSEK EATSIIHQLL SGPHGLRAGG KHGSGFTWVI DTNIMREAVL
     VLTADEVSDT LASEAKDPSL PKKPIVSSAC PGWVCYAEKT HPFILPHLSK LKSPQALAGT
     LLKSTLSKTL GVPVSRIWHL AVMPCFDKKL EASREELTDV TWNPADGQMF SQPQTPVRDV
     DCVITTRELL TLASARGISL PSILSKSSSV SFPSFPDKAL DDYLFSKRSL SAQSMMTGTS
     GGYLHHVLTS FQARNPGSEI VAERGRNADV VVYKLVSPEN GSIIEAARYY GFRNIQNLVN
     KLKPPEMSKL SGARRNDALG GKARMQLSSR KAAAKTKFDY AYVEVMACPG GCTNGGGQIR
     IEDAREANLT AQTGTPADTN GAASKPSPHE QRAWLARVDE AYFSAGDSED ETEASSKHFS
     ILEREAGIHQ ILHYWSDLMG VPLSKLAYTT FREVESDVGK PQEGVNATAQ AALREGTNW