ID   NARF_CAEBR              Reviewed;         439 AA.
AC   A8XZU0;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-DEC-2008, sequence version 2.
DT   03-AUG-2022, entry version 57.
DE   RecName: Full=Probable cytosolic Fe-S cluster assembly factor oxy-4;
GN   Name=oxy-4; ORFNames=CBG21318;
OS   Caenorhabditis briggsae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6238;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16;
RX   PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA   Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA   Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA   Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA   Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA   Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA   Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA   Durbin R.M., Waterston R.H.;
RT   "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT   genomics.";
RL   PLoS Biol. 1:166-192(2003).
CC   -!- FUNCTION: Component of the cytosolic iron-sulfur (Fe/S) protein
CC       assembly machinery. Required for maturation of extramitochondrial Fe/S
CC       proteins (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NARF family. {ECO:0000305}.
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DR   EMBL; HE600993; CAP38157.2; -; Genomic_DNA.
DR   AlphaFoldDB; A8XZU0; -.
DR   SMR; A8XZU0; -.
DR   STRING; 6238.CBG21318; -.
DR   WormBase; CBG21318; CBP05058; WBGene00040128; Cbr-oxy-4.
DR   eggNOG; KOG2439; Eukaryota.
DR   HOGENOM; CLU_018240_0_0_1; -.
DR   InParanoid; A8XZU0; -.
DR   OMA; PHEQRAW; -.
DR   OrthoDB; 705416at2759; -.
DR   Proteomes; UP000008549; Chromosome IV.
DR   GO; GO:0097361; C:CIA complex; IBA:GO_Central.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
DR   InterPro; IPR009016; Fe_hydrogenase.
DR   InterPro; IPR004108; Fe_hydrogenase_lsu_C.
DR   Pfam; PF02906; Fe_hyd_lg_C; 1.
DR   SUPFAM; SSF53920; SSF53920; 1.
PE   3: Inferred from homology;
KW   4Fe-4S; Iron; Iron-sulfur; Metal-binding; Reference proteome.
FT   CHAIN           1..439
FT                   /note="Probable cytosolic Fe-S cluster assembly factor oxy-
FT                   4"
FT                   /id="PRO_0000383694"
FT   REGION          38..60
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         25
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255"
FT   BINDING         71
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255"
FT   BINDING         74
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255"
FT   BINDING         77
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255"
FT   BINDING         176
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255"
FT   BINDING         232
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255"
FT   BINDING         364
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255"
FT   BINDING         368
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   439 AA;  48793 MW;  14D435D57047F7EF CRC64;
     MEDSGFSGVV RLSNVSDFIA PNLDCIIPLE TRTVEKKNEE PQVNIRAKKT KNEENKPKED
     KKSVKISLAD CLACNGCITS AETVLVEEQS FGRLLEGIRN SKMAVITISP QTITSLAVKL
     EKTPEDLAKL IASFFRRHGV KYVLDSSFAR QFAHSLAYEE LLLTPSTSRP LLSSACPGFV
     CYAEKSHGEL LIPKISKIRS PQAISGAIVK GYLAKKEGLS PCDVFHAAVM PCFDKKLEHR
     GNSLGTAELL EELVKEEGVA EDVEEEEENN WTTSLSRGII IGEDGGASGG YADRIVRDFV
     AQNGGIVKTS KLNKNMFSTT VESTTTGEIV LRVAKVYGFR NVQNLVRKMK TKKEKTDYVE
     VMACPGGCAN GGGQVRYETM DEREKRLAQV EELYEALPRG NSWEESVREE WKRLDTNYKN
     LLFTDYKPVE TNVAQTLKW