ID   NARF_CULQU              Reviewed;         478 AA.
AC   B0WU52;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   22-SEP-2009, sequence version 2.
DT   03-AUG-2022, entry version 58.
DE   RecName: Full=Probable cytosolic Fe-S cluster assembly factor CPIJ010948;
GN   ORFNames=CPIJ010948;
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB;
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.D.,
RA   Hannick L.I., Megy K., O'Leary S.B., Pearson M., Haas B.J., Mauceli E.,
RA   Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA   Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA   Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA   Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA   Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA   Fraser-Liggett C.M., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the cytosolic iron-sulfur (Fe/S) protein
CC       assembly machinery. Required for maturation of extramitochondrial Fe/S
CC       proteins (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NARF family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EDS34771.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; DS232100; EDS34771.1; ALT_SEQ; Genomic_DNA.
DR   RefSeq; XP_001870903.1; XM_001870868.1.
DR   AlphaFoldDB; B0WU52; -.
DR   SMR; B0WU52; -.
DR   STRING; 7176.CPIJ010948-PA; -.
DR   KEGG; cqu:CpipJ_CPIJ010948; -.
DR   VEuPathDB; VectorBase:CPIJ010948; -.
DR   eggNOG; KOG2439; Eukaryota.
DR   HOGENOM; CLU_018240_0_0_1; -.
DR   InParanoid; B0WU52; -.
DR   OrthoDB; 705416at2759; -.
DR   Proteomes; UP000002320; Partially assembled WGS sequence.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
DR   InterPro; IPR009016; Fe_hydrogenase.
DR   InterPro; IPR004108; Fe_hydrogenase_lsu_C.
DR   InterPro; IPR003149; Fe_hydrogenase_ssu.
DR   Pfam; PF02906; Fe_hyd_lg_C; 1.
DR   SMART; SM00902; Fe_hyd_SSU; 1.
DR   SUPFAM; SSF53920; SSF53920; 1.
PE   3: Inferred from homology;
KW   4Fe-4S; Iron; Iron-sulfur; Metal-binding; Reference proteome.
FT   CHAIN           1..478
FT                   /note="Probable cytosolic Fe-S cluster assembly factor
FT                   CPIJ010948"
FT                   /id="PRO_0000383698"
FT   BINDING         23
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255"
FT   BINDING         69
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255"
FT   BINDING         72
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255"
FT   BINDING         75
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255"
FT   BINDING         189
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255"
FT   BINDING         245
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255"
FT   BINDING         396
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255"
FT   BINDING         400
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   478 AA;  53470 MW;  C7383376CABBBB40 CRC64;
     MSRFSGALQL TDLDDFITPS QECIKPVKIE ANKSKTGSKI TIQDDGSYMQ ATSSGLQKLE
     KVEITLADCL ACSGCITSAE GVLITQQSQE ELLKVMNENN LAKLNNQLDA VRFIVFTVAQ
     QPILSLAKRY NLPAEETFER VAGYFRKLGA DLVVDTKIAD DLALIEGRNE FIERFNTNRQ
     TLPMLASSCP GFVCYAEKTH GSFILPYIAS TRSPQQIMGV LVKKYLAKLL GIAADRIYHV
     TVMPCYDKKL EASREDFFSD VENCRDVDCV ITSIEIEQML DGSGVQALQI VEKAPIDWPW
     STGRPPVFVW GHESSGSGGY SEYLFKYAAR KLFNVAVDHV EFKNLRNSDL REAVLEQNGE
     VVLRFAIANG FRNIQNMVQK LKRGKCNYHY IEIMACPSGC LNGGAQIRPT GGQSQRELTA
     ELEALYRSLP ASNPENEAVE MVYTTFLDNA GDNNMRKEFL HTSYHPIEKM NTALNIKW