NARF_DROAN
ID NARF_DROAN Reviewed; 476 AA.
AC B3N018;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 02-SEP-2008, sequence version 1.
DT 03-AUG-2022, entry version 54.
DE RecName: Full=Probable cytosolic Fe-S cluster assembly factor GF22738;
GN ORFNames=GF22738;
OS Drosophila ananassae (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7217;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 14024-0371.13;
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
CC -!- FUNCTION: Component of the cytosolic iron-sulfur (Fe/S) protein
CC assembly machinery. Required for maturation of extramitochondrial Fe/S
CC proteins (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the NARF family. {ECO:0000305}.
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DR EMBL; CH902638; EDV35384.1; -; Genomic_DNA.
DR RefSeq; XP_001966903.1; XM_001966867.2.
DR AlphaFoldDB; B3N018; -.
DR SMR; B3N018; -.
DR STRING; 7217.FBpp0125930; -.
DR EnsemblMetazoa; FBtr0127438; FBpp0125930; FBgn0099732.
DR GeneID; 6505392; -.
DR KEGG; dan:6505392; -.
DR eggNOG; KOG2439; Eukaryota.
DR HOGENOM; CLU_018240_0_0_1; -.
DR InParanoid; B3N018; -.
DR OMA; PHEQRAW; -.
DR OrthoDB; 705416at2759; -.
DR PhylomeDB; B3N018; -.
DR Proteomes; UP000007801; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
DR InterPro; IPR009016; Fe_hydrogenase.
DR InterPro; IPR004108; Fe_hydrogenase_lsu_C.
DR InterPro; IPR003149; Fe_hydrogenase_ssu.
DR Pfam; PF02906; Fe_hyd_lg_C; 1.
DR Pfam; PF02256; Fe_hyd_SSU; 1.
DR SMART; SM00902; Fe_hyd_SSU; 1.
DR SUPFAM; SSF53920; SSF53920; 1.
PE 3: Inferred from homology;
KW 4Fe-4S; Iron; Iron-sulfur; Metal-binding; Reference proteome.
FT CHAIN 1..476
FT /note="Probable cytosolic Fe-S cluster assembly factor
FT GF22738"
FT /id="PRO_0000383699"
FT BINDING 23
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000255"
FT BINDING 68
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000255"
FT BINDING 71
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000255"
FT BINDING 74
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000255"
FT BINDING 187
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000255"
FT BINDING 243
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000255"
FT BINDING 395
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000255"
FT BINDING 399
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000255"
SQ SEQUENCE 476 AA; 54053 MW; 80FD749B0343101A CRC64;
MSRFSGALQL TDIDDFITPA QECIKPIPIN KKNSKSGAKI SVQEDGYYEE SGTGKQKLQK
LEITLQDCLA CSGCITSAEG VLITQQSQEE LLKVLHENKK LKAEEDNNLS RTVVFSVATQ
PLISLAYRYK ISVEETARHL AGYFRSLGAD YVLSTKVADD LALLECRNEF LEKYRENNDL
TMFSSSCPGW VCYAEKTHGN FILPHIATTR SPQQIMGVLV KQYLGKKLNL PASRIYHVTV
MPCYDKKLEA SREDFFSEVN ASRDVDCVIT SVEVEQMLLE VDQTLPAQEP ADLDWPWWDE
RPELMVYSHE STYSGGYAEH VFRFAARELF NDARPIQLQI DQPRNRDLKE FFLEKDGIVL
LRFAIANGFK NIQNLVQKLK RGKGSKFHFV EIMACPSGCI NGGAQVRPIS GQHVRELTQK
LEELYTKLPR SQPDNIGTKK LYDDFFDGFG TDKSHNLLHT SYHSVDKLIP ALNIKW
